234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played by histones, proteins that provide scaffolding for DNA to wrap around. Histones also appear in archaea (one of the other domains of life), but until recently there wasn't evidence for them in bacteria (the final of the three domains). Todays guest, Tobias Warnecke, is an author on a recent paper that claims to provide such evidence. We discuss this new result, as well as background questions of how cells evolved and what their current structure can teach us about their histories.

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Tobias Warnecke received his Ph.D. in biology from the University of Bath. He is currently a Programme Leader and MRC Investigator at the London Institute of Medical Sciences. He is a co-author on A. Hochner et al. (2023), "Histone-Organized Chromatin in Bacteria."


Episoder(419)

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111 | Nick Bostrom on Anthropic Selection and Living in a Simulation

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110 | Neil Johnson on Complexity, Conflict, and Infodemiology

110 | Neil Johnson on Complexity, Conflict, and Infodemiology

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109 | Jason Torchinsky on Our Self-Driving Future

109 | Jason Torchinsky on Our Self-Driving Future

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108 | Carl Bergstrom on Information, Disinformation, and Bullshit

108 | Carl Bergstrom on Information, Disinformation, and Bullshit

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107 | Russ Shafer-Landau on the Reality of Morality

107 | Russ Shafer-Landau on the Reality of Morality

Despite occasional and important disagreements, most people are in rough agreement about what it means to be moral, to do the right thing. There's much less agreement about why we should be moral, or ...

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106 | Stuart Bartlett on What "Life" Means

106 | Stuart Bartlett on What "Life" Means

Someday, most likely, we will encounter life that is not as we know it. We might find it elsewhere in the universe, we might find it right here on Earth, or we might make it ourselves in a lab. Will w...

20 Jul 20201h 25min

105 | Ann-Sophie Barwich on the Science and Philosophy of Smell

105 | Ann-Sophie Barwich on the Science and Philosophy of Smell

We gather empirical evidence about the nature of the world through our senses, and use that evidence to construct an image of the world in our minds. But not all senses are created equal; in practice,...

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104 | David Rosen and Scott Miles on the Neuroscience of Music and Creativity

104 | David Rosen and Scott Miles on the Neuroscience of Music and Creativity

Creativity is one of those things that we all admire but struggle to define or make concrete. Music provides a useful laboratory in which to examine what creativity is all about — how do people become...

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