After PCI, What Matters Most? Heart Failure, Bleeding, or Recurrent MI? | JACC Baran

After PCI, What Matters Most? Heart Failure, Bleeding, or Recurrent MI? | JACC Baran

Hosts Mitsuaki Sawano, MD, Shun Kohsaka, and Nobuhiro Ikemura welcome Dr. Takahiro Suzuki, MD to discuss his JACC: Cardiovascular Interventions study, “Nonfatal Adverse Events and Risk for Subsequent Mortality in Patients Undergoing Percutaneous Coronary Intervention.” Using the multicenter Japanese JCD-KiCS PCI registry, the study examined how post-PCI nonfatal events—including heart failure hospitalization, recurrent acute coronary syndrome, and major bleeding—shape subsequent mortality risk. Among more than 10,000 patients undergoing PCI, heart failure hospitalization emerged as the most frequent adverse event and carried the strongest association with subsequent mortality, with a population attributable fraction suggesting it accounted for nearly one-fifth of the overall mortality burden after PCI. The episode explores why PCI follow-up may need to move beyond the traditional “ischemia versus bleeding” framework, how heart failure surveillance could become central to post-PCI care, and why endpoint design in cardiovascular trials may need to better reflect the unequal clinical weight of different adverse events.

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Episoder(70)

HFpEF and HFmrEF: Can KCCQ-12 Replace KCCQ-23? | JACC Baran

HFpEF and HFmrEF: Can KCCQ-12 Replace KCCQ-23? | JACC Baran

Hosts Mitsuaki Sawano, MD, Kentaro Ejiri, MD, and Nobuhiro Ikemura, MD welcome Dr. Yasuhiro Hamatani, MD (Brigham and Women’s Hospital) to discuss his study, “Interchangeability of the KCCQ-12 and KCC...

26 Mai 33min

Can AI Predict AF Recurrence After Cardioversion? | JACC Baran

Can AI Predict AF Recurrence After Cardioversion? | JACC Baran

Hosts Mitsuaki Sawano, MD, and Satoshi Shoji, MD welcome Dr. Keisuke Usuda, MD (Massachusetts General Hospital / Broad Institute of MIT and Harvard) to discuss his JACC: Clinical Electrophysiology stu...

19 Mai 32min

Mitral Stenosis: Beyond Rheumatic Disease | JACC Baran

Mitral Stenosis: Beyond Rheumatic Disease | JACC Baran

Hosts Mitsuaki Sawano, MD, Kentaro Ejiri, MD, and Nobuhiro Ikemura, MD welcome Dr. Nahoko Kato, MD, PhD (Tokyo Bay Urayasu Ichikawa Medical Center) and Dr. Hiroyuki Okura, MD, PhD (Gifu University) to...

12 Mai 31min

AF Ablation and the Brain: Does It Improve Blood Flow and Cognition? | JACC Baran

AF Ablation and the Brain: Does It Improve Blood Flow and Cognition? | JACC Baran

Hosts Mitsuaki Sawano, MD, Satoshi Shoji, MD, Nobuhiro Ikemura, MD, and Hiroyuki Sato, MD welcome Dr. Tasuku Yamamoto, MD (Cleveland Clinic) to discuss his JACC: Clinical Electrophysiology study, “Neu...

5 Mai 41min

Acute PE in Practice: An APAC View on the New AHA/ACC Guideline | JACC Baran

Acute PE in Practice: An APAC View on the New AHA/ACC Guideline | JACC Baran

Hosts Mitsuaki Sawano, MD, and Shun Kohsaka, MD, welcome Dr. Yugo Yamashita, MD (Kyoto University) to discuss the newly released 2026 AHA/ACC Guideline for Acute Pulmonary Embolism and its accompanyin...

28 Apr 42min

Marfan Syndrome: Timing Surgery Through Genetics | JACC Baran

Marfan Syndrome: Timing Surgery Through Genetics | JACC Baran

Hosts Mitsuaki Sawano, MD, welcome Dr. Yuki Kawashima, MD and Dr. Ryo Inuzuka, MD (The University of Tokyo) to discuss their JACC study on how genetic variants in FBN1 can predict the timing and risk ...

21 Apr 36min

Unraveling HCM Heterogeneity Using Circulating microRNAs | JACC Baran

Unraveling HCM Heterogeneity Using Circulating microRNAs | JACC Baran

Hosts Mitsuaki Sawano, MD, Shun Kohsaka, MD, and Nobuhiro Ikemura, MD welcome Dr. Yuichi J. Shimada (Columbia University) to discuss his ACC presentation on plasma microRNA profiling in hypertrophic c...

14 Apr 27min

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