Ep 381 - Q&A: GLP-1s, Tendon Training, & Rep Ranges

Trexler and Helms open with an overview of the new MASS issue (body recomposition, a protein consensus paper, reverse dieting) and a powerlifting World Championships recap before diving into a rapid-fire listener Q&A. Along the way they tackle whether protein needs scale with training volume, the science behind a supplement that's been called "Nature's Ozempic," evaluating protein quality based on food labels, dieting while chasing endurance adaptations, protecting tendons and bone when shifting from powerlifting to bodybuilding, and the myths around rep ranges and muscle shape. The back half centers on GLP-1 drugs like tirzepatide — their surprising off-label effects, who's actually a good candidate, and whether they should be banned in natural bodybuilding — before closing with a rapid-fire round on lengthened partials and the volume-versus-frequency question.

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Chapters

0:00 — Intro, audio gremlins & the new MASS issue

6:40 — Powerlifting news: World Championships & squat records

11:48 — Do protein requirements scale with training volume?

16:59 — PGX: is "Nature's Ozempic" actually legit?

22:49 — Protein quality & % Daily Value on food labels

26:47 — Chasing endurance adaptations while dieting in a deficit

36:52 — Protecting tendons & bone when leaving powerlifting

45:37 — Rep ranges, muscle "hardness" & fiber-type myths

50:21 — Tirzepatide & GLP-1s: are they really the wonder drug?

1:01:08 — Should GLP-1s be banned in natural bodybuilding?

1:11:11 — Rapid fire: lengthened partials & the volume/frequency question

1:15:39 — Wrap-up & sign-off