#453 - [Journal Club] - 📌 What Happened to NEC When Centers Stopped Using Probiotics?

#453 - [Journal Club] - 📌 What Happened to NEC When Centers Stopped Using Probiotics?

Send us Fan Mail When the FDA warning landed in late 2023, probiotic use in high-use NICUs collapsed from 86% to under 7% almost overnight. What happened to NEC? This week Daphna brings Tolia and Patel's new Journal of Perinatology analysis of the Pediatrix Clinical Data Warehouse, a natural experiment across 347 NICUs and more than 10,000 extremely preterm infants. Centers that stopped saw NEC climb from 2.7% to 4.4%. Centers that never used probiotics saw nothing change. Ben and Daphna work...

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Episoder(929)

#458 - [Journal Club] - 📌 Is this the trial that brings probiotics back to the NICU?

#458 - [Journal Club] - 📌 Is this the trial that brings probiotics back to the NICU?

Send us Fan Mail Probiotics left US NICUs after the FDA reclassified them, and NEC rates went up. This week Ben reviews the Connection Study, a 2,158 infant phase 3 trial of IBP-9414, a live biotherap...

12 Aug 26min

#458 - [Journal Club] - 📌 Does holding during cooling change NICU outcomes in HIE?

#458 - [Journal Club] - 📌 Does holding during cooling change NICU outcomes in HIE?

Send us Fan Mail Parents of babies undergoing therapeutic hypothermia often wait days before they can hold their child, and many never get the chance during cooling at all. This week on Journal Club, ...

11 Aug 18min

#458 - [Journal Club] - 📌 Should late preterm infants born by cesarean receive prophylactic CPAP?

#458 - [Journal Club] - 📌 Should late preterm infants born by cesarean receive prophylactic CPAP?

Send us Fan Mail Late preterm babies born by cesarean fill our NICUs, and most of them are there for respiratory distress that resolves in a day or two. Could 20 minutes of CPAP in the operating room ...

10 Aug 36min

#457 - Are We Rethinking When and How We Give Surfactant (ft Dr. Roger Soll)

#457 - Are We Rethinking When and How We Give Surfactant (ft Dr. Roger Soll)

Send us Fan Mail When is surfactant "early," and when is it too early, or too late? In this second installment of our two-part series with the Neonatal Resuscitation Symposium, Ben Courchia sits down ...

3 Aug 34min

#456 - 📑 Journal Club - The Complete Episode from August 1st 2026

#456 - 📑 Journal Club - The Complete Episode from August 1st 2026

Send us Fan Mail Which babies with critical congenital heart disease face the highest risk of brain injury, and does earlier surgery actually help? Why is infant CHD mortality climbing again after yea...

1 Aug 1h 13min

#456 - [Neo News] - 📌 Why Did the US Fund a Hepatitis B Trial That Withheld the Birth Dose?

#456 - [Neo News] - 📌 Why Did the US Fund a Hepatitis B Trial That Withheld the Birth Dose?

Send us Fan Mail In this episode of Neo News, Ben and Eli break down a troubling story in vaccine policy: an unsolicited $1.6 million CDC grant funding a Danish research group's trial in Guinea-Bissau...

31 Jul 21min

#456 - [Journal Club] - đŸ«€ From The Heart - Do These Newborns Have Diastolic Dysfunction, or Just Different Physiology?

#456 - [Journal Club] - đŸ«€ From The Heart - Do These Newborns Have Diastolic Dysfunction, or Just Different Physiology?

Send us Fan Mail In this prospective study, Adrianne and Nim dig into an area with almost no normative pediatric data: right ventricular diastolic function. Comparing 57 infants with RV pressure overl...

30 Jul 14min

#456 - [Journal Club] - đŸ«€ From The Heart - Why Does a Sicker Mom Sometimes Mean a Stronger Neonatal Heart?

#456 - [Journal Club] - đŸ«€ From The Heart - Why Does a Sicker Mom Sometimes Mean a Stronger Neonatal Heart?

Send us Fan Mail In this small prospective pilot study, Adrianne and Nim explore a domain rarely discussed on rounds, how a mother's cardiovascular function in preeclampsia shapes her newborn's circul...

29 Jul 14min

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