Season 1.  Episode 8.  Unscripted with Nevra Ledwon

Season 1. Episode 8. Unscripted with Nevra Ledwon

Nevra Ledwon has spent 25 years in mathematical optimization, the branch of AI that decides which trucks carry which goods, how factories schedule production lines, how airlines crew flights, and how warehouses route their pickers, work that predates the chatbot era by decades and often delivers harder, more measurable business value.

In this conversation, she tells Jeff about the moment that changed her mind: she assumed generative AI, trained on decades of operations research textbooks, could replace the senior PhDs who spend weeks interviewing stakeholders to translate a messy business problem into a solvable model. It couldn't, and the experience gave her new respect for the expertise those specialists bring.

She walks through concrete wins, including a seven-figure reduction in cold storage costs from a hundred-thousand-dollar optimization project, and a European soccer league's season-schedule problem with more possible arrangements than atoms in the universe, solved only through trial-and-error mathematical experimentation no AI could shortcut.

She distinguishes prediction from optimization (prediction anticipates what will happen, optimization prescribes what to do about it) and argues most companies chase marginal prediction accuracy instead of building the ability to adjust plans in real time. Her company, Simple Rose, uses generative AI not to replace operations research experts but to compress the multi-week interview process that used to precede every optimization project, aiming to make a field long reserved for companies like Amazon accessible to a manufacturer of socks or a mid-sized European transit agency.

She closes on what she's watching for next: an AI that stops answering the narrow question asked and starts challenging the premise behind it.

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Episoder(19)

Season 1.  Episode 19.  Unscripted with Matthew Guggemos

Season 1. Episode 19. Unscripted with Matthew Guggemos

Matthew Guggemos spent more than 20 years as a speech-language pathologist teaching children to communicate — kids for whom language doesn't come free — and now builds AI at scale as CTO of iTherapy, ...

8 Aug 52min

Season 1.  Episode 18.  Unscripted with Camberley Bates

Season 1. Episode 18. Unscripted with Camberley Bates

Camberley Bates has spent 30-plus years as one of enterprise technology's most respected independent analysts, paid to cut through vendor hype and tell executives what's real. On this episode of Unscr...

27 Jul 46min

Season 1.  Episode 17.  Unscripted with Russ Wilcox

Season 1. Episode 17. Unscripted with Russ Wilcox

Russ Wilcox, CEO of ArtifexAI, went from a broken sewer decision in his Cape Cod hometown to advising the Pentagon and State Department on the US-China AI race. In this episode of Unscripted, he tells...

27 Jul 52min

Season 1.  Ep[isode 16.  Unscripted with Keith Pijanowski

Season 1. Ep[isode 16. Unscripted with Keith Pijanowski

Every impressive AI demo sits on an enormous, expensive, and very unglamorous foundation of data. Keith Pijanowski is one of the people who built it. After a decade-plus at Microsoft (where he helped ...

22 Jul 45min

Season 1.  Episode 15.  Unscripted with Klas Nilsson

Season 1. Episode 15. Unscripted with Klas Nilsson

Everyone is promising humanoid robots in every home and factory. Klas Nilsson has spent 40 years on the part that turns out to be hard. The Cognibotics founder, who built one of the first digital robo...

20 Jul 45min

Season 1.  Episode 14.  Unscripted with Lena Smart

Season 1. Episode 14. Unscripted with Lena Smart

Lena Smart has spent 30 years securing the systems we genuinely cannot afford to have fail — the power grid, financial markets, and as longtime CISO at MongoDB, one of the most widely used databases o...

12 Jul 33min

Season 1.  Episode 13.  Unscripted with Sarah Chardonnens

Season 1. Episode 13. Unscripted with Sarah Chardonnens

Dr. Sarah Chardonnens is a professor at the University of Freiburg with a PhD in the science of learning, and in this conversation with Jeff Pedowitz she takes on the question everyone has an opinion ...

10 Jul 36min

Season 1.  Episode 12.  Unscripted with Juergen Weichenberger

Season 1. Episode 12. Unscripted with Juergen Weichenberger

Juergen Weichenberger has been building AI since the 1990s, well before it became a mainstream conversation, in domains where the cost of being wrong isn't a typo, it's a shutdown: factories, energy g...

10 Jul 34min

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