#35 How to Deal with Rejection Sensitivity | With Dr. Sasha Hamdin

#35 How to Deal with Rejection Sensitivity | With Dr. Sasha Hamdin

Eli sits down with board-certified psychiatrist and ADHD specialist Dr. Sasha Hamdani to unpack one of the most misunderstood emotional experiences: Rejection Sensitive Dysphoria (RSD). Together they explore the neuroscience behind why some of us feel rejection so intensely — and why that sensitivity might actually be a gift. Dr. Hamdani also shares personal stories and practical tools from her upcoming book, Too Sensitive: Rejection, Resilience, and the Science of Feeling Deeply.

Key Takeaways
  • RSD is not a personality flaw — it's a neurological response rooted in how your brain is wired, involving amygdala hyperactivity, dopamine dysregulation, and weaker prefrontal override.
  • Sensitivity has roots in multiple places: genetics, attachment history, identity-based rejection (racism, homophobia, misogyny), and hormonal fluctuations all play a role.
  • Emotional sensitivity ≠ weakness. When paired with the right tools, it becomes emotional intelligence — a true superpower in relationships and caregiving.
  • Your body tells you what you're feeling before your brain catches up. Learning where RSD lands in your body (chest, stomach, head) is the critical first step.
  • Movement is a powerful acute tool for interrupting RSD spirals — it pushes oxygenated glucose to the frontal lobe to help override the emotional response.
  • Attachment styles shape how we cope with RSD: some people cling, some flee — both are adaptations, not character defects.
  • Making more noise about RSD matters — it's not yet a formal DSM diagnosis, but clinical advocates like Dr. Hamdani are working to change that.

About the Guest

Dr. Sasha Hamdani, MD is a board-certified psychiatrist and ADHD clinical expert specializing in RSD and emotional regulation. She reaches over 2 million followers across social media with evidence-backed mental health content, and has been recognized by Harvard as a public health leader. She is the creator of the FocusGenie ADHD management app and the author of Self-Care for People with ADHD (2023). Her groundbreaking new book, Too Sensitive: Rejection, Resilience, and the Science of Feeling Deeply, publishes August 25, 2026.


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