#560: Building a Research OS: From Django to 30,000 Samples

#560: Building a Research OS: From Django to 30,000 Samples

In 2020, a gastroenterologist in Glasgow did the math on his new research study and came up with 30,000 samples, arriving over two years from three cities and a dozen hospitals. He asked around about how researchers keep track of that. The answer was Microsoft Excel. Shaun Chuah had written some HTML by hand in Notepad back in high school and that was about the whole of his programming experience, so he opened the Django tutorial and started reading. Six years later that app is Foundry120, holding 10 terabytes of clinical and genomics data with an agentic AI running on top of it.

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Episoder(559)

#559: 12 Things You Should (and Shouldn't) Do in AWS

#559: 12 Things You Should (and Shouldn't) Do in AWS

Your site is down. It's 3am. Is it a bug, a bill, or a breach? You can't tell yet, and everyone is watching you find out. Matt Lea has spent fifteen years being the person companies call when an outag...

19 Aug 1h 7min

#558: Hyper-Personal Software with Python

#558: Hyper-Personal Software with Python

Every company has one. The little internal tool that Jane built back in 2021, and then Jane left. Nobody understands it, nobody will touch it. There are two unwritten rules around it: don't change it,...

10 Aug 1h 2min

#557: Security of everything at PyCon 2026

#557: Security of everything at PyCon 2026

Security has always been the vegetables of software. Everyone agrees it matters, and somehow it never quite makes it onto the plate. At PyCon US this year, that changed. For the first time ever, secur...

2 Aug 1h 8min

#556: Updates on Django's Async Story

#556: Updates on Django's Async Story

For years, "Django and async" came with an asterisk. The docs themselves warned you off it. Scary performance notes, a story that felt half-finished. Well, that story just got rewritten, literally, an...

26 Jul 1h 4min

#555: Marimo Pair - A Canvas for Agent + Developers Collaboration

#555: Marimo Pair - A Canvas for Agent + Developers Collaboration

Coding agents have gotten really good at one kind of work. You scope a feature, edit some files, run the tests, ship it. It all happens on disk. But that is not how data work feels. You load something...

13 Jul 1h 4min

#554: Trustworthy AI in Healthcare and Longevity

#554: Trustworthy AI in Healthcare and Longevity

You ask an AI a question and it answers with total confidence. Most of the time, a confidently wrong answer is just an annoyance. But what if the question is medical, and there's a real patient on the...

10 Jul 1h

#553: All of our tools

#553: All of our tools

This episode is a fun crossover from our Python news and tips podcast, Python Bytes. We have had some big changes over there. Brian Okken has moved on and Calvin Hendryx-Parker has joined the show as ...

26 Jun 55min

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