Free Radicals
In Our Time1 Nov 2018

Free Radicals

Melvyn Bragg and guests discuss the properties of atoms or molecules with a single unpaired electron, which tend to be more reactive, keen to seize an electron to make it a pair. In the atmosphere, they are linked to reactions such as rusting. Free radicals came to prominence in the 1950s with the discovery that radiation poisoning operates through free radicals, as it splits water molecules and produces a very reactive hydroxyl radical which damages DNA and other molecules in the cell. There is also an argument that free radicals are a byproduct of normal respiration and over time they cause an accumulation of damage that is effectively the process of ageing. For all their negative associations, free radicals play an important role in signalling and are also linked with driving cell division, both cancer and normal cell division, even if they tend to become damaging when there are too many of them.

With

Nick Lane Professor of Evolutionary Biochemistry at University College London

Anna Croft Associate Professor at the Department of Chemical and Environmental Engineering at the University of Nottingham

And

Mike Murphy Professor of Mitochondrial Redox Biology at Cambridge University

Producer: Simon Tillotson

Episoder(1087)

Barbour's 'Brus'

Barbour's 'Brus'

Melvyn Bragg and guests discuss John Barbour's epic poem The Brus, or Bruce, which he wrote c1375. The Brus is the earliest surviving poem in Older Scots and the only source of many of the stories of ...

17 Jul 202549min

The Evolution of Lungs

The Evolution of Lungs

Melvyn Bragg and guests discuss the evolution of lungs and of the first breaths, which can be traced back 400 million years to when animal life spread from rock pools and swamps onto land, as some fis...

10 Jul 202548min

The Vienna Secession

The Vienna Secession

In 1897, Gustav Klimt led a group of radical artists to break free from the cultural establishment of Vienna and found a movement that became known as the Vienna Secession. In the vibrant atmosphere o...

3 Jul 202554min

Hypnosis

Hypnosis

Ever since Franz Anton Mesmer induced trance-like states in his Parisian subjects in the late eighteenth century, dressed in long purple robes, hypnosis has been associated with performance, power and...

26 Jun 202545min

Paul von Hindenburg

Paul von Hindenburg

Melvyn Bragg and guests discuss the life and role of one of the most significant figures in early 20th Century German history. Paul von Hindenburg (1847-1934) had been famous since 1914 as the victori...

19 Jun 202552min

Copyright

Copyright

In 1710, the British Parliament passed a piece of legislation entitled An Act for the Encouragement of Learning. It became known as the Statute of Anne, and it was the world’s first copyright law. ...

12 Jun 20251h

Lise Meitner

Lise Meitner

Melvyn Bragg and guests discuss the decisive role of one of the great 20th Century physicists in solving the question of nuclear fission. It is said that Meitner (1878-1968) made this breakthrough ov...

5 Jun 202557min

The Korean Empire

The Korean Empire

Melvyn Bragg and guests discuss Korea's brief but significant period as an empire as it moved from the 500-year-old dynastic Joseon monarchy towards modernity. It was in October 1897 that King Gojong ...

29 Mai 202547min

Populært innen Historie

rss-dette-ma-aldri-skje-igjen
med-egne-oyne
historier-som-endret-norge
henrettelsespodden
rss-benadet
historier-som-endret-verden
rss-katastrofe
sektledere
rss-nadelose-nordmenn-gestapo
aftenposten-historie
rss-gamle-greier
rss-strid-de-norske-borgerkrigene
rss-frontkjemperne
rss-bisarr-historie
rss-historiske-romanser-svik-drap-og-kjarlighet
historiepodden-ww2
liberal-halvtime
historiepodden
rss-historiepodden-ww2
vare-historier