303: The Molecule That's More Important Than Oxygen And How To Get More Of It - with Dr. Nathan S. Bryan

In this episode of ReversABLE, Josh Dech welcomes back Dr. Nathan S. Bryan, a researcher who has spent 25 years studying nitric oxide and its role in human physiology. Together, they explore how nitric oxide supports vascular function, oxygen delivery, inflammation regulation, and the body's natural repair processes—and why its relationship with chronic illness deserves closer scientific attention.

The conversation begins with an unexpected topic: your mouth. Dr. Bryan discusses the relationship between the oral microbiome, certain mouthwash ingredients, and the body's ability to produce nitric oxide. They examine how oral bacteria participate in the nitrate–nitrite–nitric oxide pathway and why disrupting this process may have implications beyond dental health.

Josh and Nathan then connect nitric oxide to broader questions in functional medicine and root-cause healing. They discuss inflammation, oxidative stress, immune dysfunction, microcirculation, environmental exposures, and the physiological processes involved in delivering oxygen and nutrients to tissues. For listeners navigating chronic gut symptoms or inflammatory conditions, this offers a wider perspective on the systems that interact with the immune system and overall health.

The episode also explores the proposed vascular and metabolic components of Alzheimer's disease, nitric oxide research in stroke recovery, and the potential relationship between nitric oxide signaling and immune-cell behavior. Nathan explains his approach to restorative physiology and why he believes research should focus on the biological mechanisms contributing to disease, rather than only its downstream manifestations.

The conversation becomes more controversial as Josh and Nathan question conventional pharmaceutical incentives, discuss the challenges of funding disruptive research, and share strong opinions about mainstream medical practice and the COVID-19 response. These perspectives are part of the discussion, not proof that the claims made are established scientific consensus.

Finally, Nathan discusses nitric oxide products, the importance of understanding dose and safety, and practical habits he recommends considering, including exercise, nasal breathing, sunlight exposure, and reviewing oral-care choices.

TOPICS DISCUSSED:

Nitric Oxide Biology And Its Role In Human Physiology
Chronic Inflammation, Oxidative Stress, And Root-Cause Mechanisms
Alzheimer's Disease, Vascular Health, And Cognitive Function
Oxygen Delivery, Blood Flow, And Hyperbaric Oxygen Therapy
Pharmaceutical Incentives And The Debate Over Symptom Management Versus Root-Cause Treatment
Nitric Oxide Dosing, Supplement Products, And Safety Considerations
Autoimmunity, Macrophage Signaling, And Immune Dysfunction
Environmental Toxicity, Detoxification, And The Body's Natural Repair Processes
The Oral Microbiome, Mouthwash, Fluoride, And Nitric Oxide Production
COVID-19, Respiratory Infections, And Controversial Claims About Disease Prevention

More from Dr. Nathan S. Bryan:

Website: n1o1.com
Instagram: @drnathansbryan
LinkedIn: Nathan Bryan
Facebook: N1o1 by Pneuma Nitric Oxide
Youtube: Dr Nathan Bryan Nitric Oxide

Get Dr. Nathan S. Bryan's Book: The Secret Of Nitric Oxide

Get Dr. Nathan S. Bryan's Products: n1o1.com/shop

Leave us a Review:

https://www.reversablepod.com/review

Need help with your gut? Visit my website gutsolution.ca to join a program:

Get help now

Contact us:

reversablepod.com/tips

FIND ME ON SOCIAL MEDIA:

Instagram

Facebook

YouTube

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(309)

308: Colon Hydrotherapy: Risks, Benefits And Pooping Better - with Marina Ortega

What if one of the biggest mistakes people make when trying to improve their gut health is focusing on detoxification before addressing elimination? In this episode of ReversABLE, Josh Dech sits down ...

13 Nov 47min

307: What Causes Autism?: Inflammation, Immunity And Vaccines -with Dr. Theresa Lyons

Is autism purely genetic, or could environmental exposures, gut health, immune dysfunction and neuroinflammation play a much bigger role than we currently understand? In this fascinating conversation,...

6 Nov 58min

306: MCAS, Histamines And The Molecule That Is Changing It All - with Brandon Perez

What if the future of gut health and immune regulation involves something we're not paying nearly enough attention to: glyconutrients? In this episode of ReversABLE, Josh Dech sits down with Brandon P...

30 Okt 58min

305: The Cellural "Antenna" And How We Misunderstood Sugar, Fat And Energy - with Robert Kiltz

What if understanding gut health requires looking beyond protein, fat, and carbohydrates to the microscopic structures that coat our cells? In this episode of ReversABLE, Josh Dech welcomes back Dr. R...

23 Okt 52min

304: The Shoes Tha Slow Aging, Fix Joint Pain And Sore Muscles - with Mark Sisson

What if your feet play a bigger role in your long-term health than you've been led to believe? In this episode of ReversABLE, Josh Dech sits down with Mark Sisson, longtime athlete, author of The Prim...

16 Okt 47min

302: Why You're Stuck WIth Chronic Inflamation And What To Do About It - with Dr. Tom O'Bryan

Dr. Tom O'Bryan returns to ReversABLE for a wide-ranging conversation about gut health, chronic inflammation, the microbiome, environmental toxins, heavy metals, and the deeper mechanisms that may con...

5 Okt 1h 8min

301: Your Pets Are Dying Young - Here Is How To Help Them Live Longer And Healthier - with Dr. Judy Morgan

What if modern veterinary care is treating the symptoms of chronic disease without addressing the conditions that created them? In this episode of ReversABLE, Josh Dech sits down with veterinarian Dr....

25 Sep 1h 9min