Why We Have The Worst Health Outcomes Of All Industrialized Nations with Dr. Charles Modlin, Dr. Leonor Osorio, and Tawny Jones

This episode is brought to you by Cozy Earth, Rupa Health, Apollo, and Wonderfeel. Over the years, it has become a widely held belief that cancer is predominately a genetic disease or simply the consequence of bad luck. An empowering evolution in cancer research, however, suggests we have far more control over our risk than previously thought.  I’m excited to talk to Dr. Thomas Seyfried about the underlying causes of cancer and why addressing metabolic dysfunction is a very important and often overlooked area of its prevention and treatment.  Dr. Thomas Seyfried is an American professor of biology, genetics, and biochemistry at Boston College. He received his Ph.D. from the University of Illinois Urbana-Champaign in 1976 and did his postdoctoral fellowship at the Yale University School of Medicine. Dr. Seyfried has over 150 peer-reviewed publications, and his research focuses primarily on the mechanisms driving cancer, epilepsy, and neurodegenerative diseases and calorie-restricted ketogenic diets in their prevention and treatment. He is the author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer and presently serves on the Nutrition & Metabolism, Neurochemical Research, Journal of Lipid Research, and ASN Neuro editorial boards. This episode is brought to you by Cozy Earth, Rupa Health, Apollo, and Wonderfeel. Get 40% off your Cozy Earth sheet at cozyearth.com and use code MARK40. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Apollo was designed by neuroscientists and physicians to tap into your body's natural rhythms to bring calm and focus and restore equilibrium to your nervous system. Check out the Apollo wearable and save $40 at apolloneuro.com/drhyman. Wonderfeel Youngr NMN works by increasing your levels of NAD, a critical molecule our bodies produce that we literally need to survive. Feel the wonder of innovation at getwonderfeel.com. Here are more details from our interview (audio version / Apple Subscriber version): How Dr. Seyfried’s work on treating epilepsy with a ketogenic diet informed his understanding of cancer (6:57 / 3:14)  Mitochondrial damage and cancer (16:58 / 14:44)  Glucose fermentation and oxidative stress and their links to cancer (25:52 / 24:47)  Our current misunderstanding of the cause of cancer (32:19 / 29:54)  Current cancer treatments vs metabolic oncology (38:31 / 36:50)  Populations without cancer incidence (56:10 / 51:55)  Metabolic cancer treatment for dogs (1:09:27 / 1:05:11)  Using a ketogenic diet with current cancer treatments (1:12:56 / 1:08:50)  Learn more at tomseyfried.com and at the Foundation for Metabolic Cancer Therapies.

21 Jun 20231h 29min

This episode is brought to you b Rupa University, Paleovalley, HigherDOSE, and Athletic Greens.  There are many areas of life that we can dial in for optimal health and longevity. Three of those areas are what we eat, our quality of sleep, and our energy production. We eat pounds of food every single day that act as information for our cells and influence our DNA expression. When we sleep, our brain’s immune system (the glymphatic system) clears away damaged cells. And increasing our energy will not only help us feel better but will also support all the systems of the body to function better. In today’s episode, I talk with Dhru Purohit in my Masterclass series about the Functional Medicine approach to food, improving our sleep, and powering up our bodies. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa University, Paleovalley, HigherDOSE, and Athletic Greens.  If you’re a healthcare provider who wants to learn more about Functional Medicine testing, you owe it to yourself to go check it out today. Go to rupauniversity.com to sign up for a free live class or a boot camp! Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Elevate your wellness game today by going to HigherDOSE.com. You can use promo code HYMAN at checkout to save 15% off site-wide or just go to HigherDOSE.com/hyman. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, Athletic Greens is offering 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews (and all referenced show notes) can be found here: How to Use Food As Medicine Daily Steps to Boost Energy and Never Be Tired Again Why Sleep is More Important Than Diet—Optimize it Today

19 Jun 202358min

This episode is brought to you by BiOptimizers and Athletic Greens. Taking care of yourself, practicing self-love and self-compassion, working on a growth mindset, building relationships and community, and having a sense of purpose are all crucial to living a fulfilling, long, healthy life. Your thoughts, feelings, and beliefs are all transmuted into biological signals that change your gene expression, impacting your immune function, hormones, microbiome, neurotransmitters, neuroplasticity, mitochondria, and more. Yet many of us tend to put self-care last on our list of to-dos (I certainly have for much of my life, to the detriment of my own health). In today’s episode of my series I’m calling Health Bites, I share my strategies for prioritizing self-care for a healthy mind and spirit. This episode is brought to you by BiOptimizers and Athletic Greens. BiOptimizers is offering my listeners 10% off Sleep Breakthrough. If you buy two or more you’ll get a free bottle of Magnesium Breakthrough. This is a limited-time offer. Go to sleepbreakthrough.com/hyman and use the code hyman10. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, Athletic Greens is offering 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from our interview (audio version / Apple Subscriber version): Learnings from the Blue Zones (4:00 / 1:10)  How your thoughts, feelings, and beliefs impact your health (4:44 / 1:55)  The health benefits of self-compassion and social connections (6:43 / 3:54)  The importance of mindset and having a sense of purpose (8:35 / 5:48)  Simple ways to prioritize self-care and reset our stress response (12:23 / 9:39)

16 Jun 202318min

This episode is brought to you by Rupa Health, Mitopure, Nordic Naturals, and Apollo. We are a culture obsessed with happiness, except we’ve been going about it all wrong. Before I became a doctor, I actually studied Buddhism. I wanted to understand the root of human suffering, and through that, understand the way to create happiness.  On today’s episode, I’m excited to talk to Dan Harris about the science of happiness, how to deal with the challenges of modern-day life, and how to create more happiness for ourselves and for those around us.  Dan Harris is an author, podcaster, and entrepreneur. For 21 years, he worked as an anchor and correspondent for ABC News, hosting such shows as Nightline and the weekend editions of Good Morning America. Dan has reported from all over the planet, covering wars in Afghanistan and Iraq and producing investigative reports in Haiti, Cambodia, and the Amazon. After having a nationally televised panic attack on Good Morning America, Dan discovered meditation and then wrote the best-selling book 10% Happier as a way to encourage fellow skeptics to give the practice a shot. After that first book, Dan launched the Ten Percent Happier app, wrote a second book, and started the Ten Percent Happier podcast, where he interviews celebrities, entrepreneurs, authors, scientists, and meditation teachers about how to do life better. This episode is brought to you by Rupa Health, Mitopure, Nordic Naturals, and Apollo. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Get 10% off Mitopure at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Shop Nordic Naturals omegas today at nordic.com and save 20% using code FARMACY. Check out the Apollo wearable and save $40 by visiting apolloneuro.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): The misinterpretation of an incident with the Dalai Lama shown in a recent viral video (2:28 / 00:50)  How to be happier and healthier (9:18 / 6:19)  Wise selfishness (16:34 / 14:15)  The neurobiology of altruism (20:19 / 18:06)  How to train your brain for happiness (26:01 / 21:44)  The connection between psychedelics and meditation (33:31 / 29:02)  How Dan’s life has changed from meditation (37:25 / 33:47)  Meditation as one component of trauma therapy (57:40 / 53:19)  Self-criticism and judgment of others (1:01:02 / 56:34)  Dan’s experience spending time with the Dalai Lama (1:08:00 / 1:03:35) The Dalai Lama's Guide to Happiness podcast series and video challenge

14 Jun 20231h 21min

This episode is brought to you by Rupa Health, InsideTracker, and LMNT. Compounds that have long been considered recreational drugs by conventional standards are finally being recognized through science as powerful tools for overcoming hard-to-treat health issues like PTSD, depression, addiction, and more. For the right person, psychedelics can provide a sense of peace and hope that helps heal their inner wounds and allows them to live with more freedom. In today’s episode, I talk with Rick Doblin, Alberto Villoldo, and Wade Davis about the ancient healing mechanisms of plant medicine. Rick Doblin, PhD, is the founder and executive director of the Multidisciplinary Association for Psychedelic Studies (MAPS). He received his doctorate in public policy from Harvard’s Kennedy School of Government. His professional goals are to help develop legal contexts for the beneficial uses of psychedelics and marijuana, primarily as prescription medicines but also for personal growth for otherwise healthy people, and eventually to become a legally licensed psychedelic therapist. Medical anthropologist Alberto Villoldo, PhD, is an international bestselling author who has researched the shamanic healing practices of the Amazon and Andes for over 25 years. He is the founder of the Four Winds Society, an organization dedicated to the bridging of ancient shamanic traditions with modern medicine and psychology. Wade Davis is a writer, photographer, and filmmaker. Explorer-in-Residence at the National Geographic Society from 2000 to 2013, he is currently Professor of Anthropology and the BC Leadership Chair in Cultures and Ecosystems at Risk at the University of British Columbia. He is the author of 23 books, including One River, The Wayfinders, and Into the Silence, and he was the winner of the 2012 Baillie Gifford Prize for Non-Fiction (formerly the Samuel Johnson Prize), the top nonfiction prize in the English language. This episode is brought to you by Rupa Health, InsideTracker, and LMNT.  Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is offering my community 20% off at insidetracker.com/drhyman. LMNT is offering my listeners a free sample pack with any purchase. Get yours at DrinkLMNT.com/hyman today. Full-length episodes of these interviews can be found here: Rick Doblin Alberto Villoldo Wade Davis

12 Jun 20231h 10min

This episode is brought to you by Rupa Health and InsideTracker. We’ve become exposed to a greater number of environmental toxins than ever before. Environmental toxins can feed cancer, interfere with glucose and cholesterol metabolism, and induce insulin resistance and obesity through multiple mechanisms, including inflammation, oxidative stress, mitochondrial injury, altered thyroid metabolism, and impaired central appetite regulation.  In today’s episode of my series I’m calling Health Bites, we’re talking about how environmental toxins impact our health, the top endocrine-disrupting toxins, and my strategies for reducing your exposure. I also share which foods you should be sure to buy organic. This episode is brought to you by Rupa Health and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): How environmental toxins impact our health (3:46 / 00:58) The top endocrine-disrupting toxins (5:52 / 4:01) Strategies to reduce your toxic burden (10:41 / 8:49)  EWG’s Clean Fifteen and Dirty Dozen lists (16:02 / 15:00)  Mentioned in this episode EWG's Skin Deep Database EWG's Guide to Healthy Cleaning Thrive Market Seatopia.fish EWG’s 2023 Shopper’s Guide to Pesticides in Produce

9 Jun 202322min

This episode is brought to you by Cozy Earth, ButcherBox, BiOptimizers, and Levels. Contrary to popular belief, women cannot follow the same health and fitness protocols as men and expect to see the same results. Unlike men, women in their reproductive years have specific hormonal considerations, and their rise and fall throughout the month impact everything from energy to focus, mood, metabolism, and the ability to adapt to good-for-you stressors like exercise or fasting. On today’s episode, I’m excited to talk to Dr. Mindy Pelz all about the benefits of fasting and how women, in particular, can cultivate a fasting routine in a way that honors their hormones.  Dr. Mindy is a renowned holistic health expert and one of the leading voices in educating women about their hormonal health. She has empowered hundreds of thousands of people around the world to tap into their bodies' innate healing abilities through her “5-Step Approach,” which uses fasting, personalized nutrition, stress management, chemical detoxification, and lifestyle changes to optimize health and slow the aging process. This episode is brought to you by Cozy Earth, ButcherBox, BiOptimizers, and Levels. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. When you sign up today, ButcherBox will send you two pounds of 100% grass-fed, grass-finished beef free in your first box plus $20 off. To receive this offer, go to ButcherBox.com/farmacy. BiOptimizers is offering my listeners 10% off Sleep Breakthrough. If you buy two or more, you’ll get a free bottle of Magnesium Breakthrough. This is a limited-time offer. Go to sleepbreakthrough.com/hyman and use the code hyman10. Levels provides real-time feedback on how diet and lifestyle choices impact your metabolic health. Right now, Levels is offering an additional two free months of their annual membership. Learn more at levels.link/HYMAN. Here are more details from our interview (audio version / Apple Subscriber version): Hormone illiteracy and why we need more hormonal education (6:48 / 3:30) Why so many women struggle with hormonal issues (10:32 / 6:55)  Managing hormones with fasting (14:31 / 11:56)  What happens when we fast (18:43 / 16:08)  Different types of fasting (23:45 / 20:20)  Reintroducing food after a fast (28:39 / 24:00)  Who shouldn’t fast (38:22 / 33:27)  Detoxification and fasting (39:35 / 34:39)  When to use hormone therapy (42:53 / 38:00)  Hormonal testing (52:13 / 47:20)  Learn more at drmindypelz.com and get a copy of Fast Like a Girl: A Woman's Guide to Using the Healing Power of Fasting to Burn Fat, Boost Energy, and Balance Hormones.

7 Jun 20231h 5min

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast.  In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on lessons from our past on how to live better and longer in our future with IFM practitioner, Dr. Elizabeth Board. To learn more about the Institute of Functional Medicine, sign up for IFM’s newsletter: https://www.ifm.org/about/free-newsletter/. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes  - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at plus@drhyman.com with any questions you have.   Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.

6 Jun 202346min