Rewind Your Clock: David Sinclair, PhD Wants To 'Cure' Aging

Rewind Your Clock: David Sinclair, PhD Wants To 'Cure' Aging

Aging is inevitable. Everybody grows old. Everyone dies. We accept these statements as fact. But what if they're just stories based on history and our current understanding of biology? What if everything we think we know about aging is about to change? Across the globe, scientists are working on treatments and therapies that are designed to extend healthy human lifespans well beyond what we know today. At the bleeding edge of such breakthroughs you will find David Sinclair, PhD, one of the world’s leading scientific authorities on longevity, aging and how to slow its effects. Returning for his second appearance on the podcast, David is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. He obtained his Ph.D. in Molecular Genetics at the University of New South Wales, Sydney in 1995 and worked as a postdoctoral researcher at M.I.T. where, among other things, he co-discovered the cause of aging for yeast. The co-founder of several biotechnology companies, David is also co-founder and co-chief editor of the journal Aging. His work has been featured in a variety of books, documentaries, and media, including 60 Minutes, Nightline and NOVA. He is an inventor on 35 patents, has been lauded as one of the Top 100 Australian Innovators, and made TIME magazine’s list of the 100 most influential people in the world. In addition, David is the author of Lifespan: The Revolutionary Science of Why We Age -- and Why We Don't Have To -- a New York Times bestseller that proposes a radical new theory of aging. As he writes: “Aging is a disease, and that disease is treatable.” Last year I convened my first conversation with David (RRP #436), a scintillating and science-heavy primer on all things human lifespan, aging and longevity. It was a runaway hit with the listeners -- and left me wanting to know more. So today we pick up where we last left off, diving deeper into the physiological mechanisms that contribute to biological degeneration. And we go further into the current state of research to better understand what contributes to aging and what can be done to counteract it. Call him a dreamer, but David believes living to 200+ is a plausible reality. If you could double your lifespan, how would this impact how you choose to live? What would it mean for the future of humanity? And for the ecological stability of the planet? The implications are profound. Equal parts philosophic and scientific, this conversation will forever change the way you think about why you age and what you can do about it. And it will leave you armed simple lifestyle practices you can deploy -- intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat -- that will help you live younger and healthier for longer. Brilliant and lovely, it’s an honor to once again share this man's wisdom with you today. So break out that pen and paper, because you're going to want to take notes on this one. The visually inclined can watch it all go down on YouTube. And as always, the audio version streams wild and free on Apple Podcasts and Spotify. I sincerely hope you enjoy the episode. Peace + Plants, Rich

Episoder(960)

Kyle Gillett, MD: Hormones & Holistic Health Habits

Kyle Gillett, MD: Hormones & Holistic Health Habits

Hormones are the body’s chemical messengers, signaling a slew of physiological processes, including your metabolism, mood, sexual function, and more. Here to help us understand this complicated endocrine language is hormone health specialist Kyle Gillett, MD. A dual board-certified physician in family medicine and obesity medicine, Kyle is an expert in optimizing hormone levels to improve overall health and well-being in both men and women. He earned his medical degree at the University of Kansas School of Medicine, practices at the Gillett Health Clinic in Olathe, Kansas, and is the host of The Gillett Health Podcast. In this wide-ranging conversation, we cover what hormones are, the key role hormones play in our overall health, and how we can leverage what Kyle calls the six pillars of health to optimize hormone health. Kyle explains how diet, exercise, sleep, stress management, sunlight exposure, and spiritual practice are more powerful than any medication or supplement out there. Show notes + MORE Watch on YouTube Newsletter Sign-Up Peace + Plants, Rich

28 Nov 20222h 41min

A Masterclass On Plant-Based Nutrition

A Masterclass On Plant-Based Nutrition

For the past year and a half, we’ve been creating quarterly episodes centered on a singular theme offered as an RRP Masterclass. These compilation episodes are derived from multiple past guests, and today, we focus our attention on plant-based nutrition. To gain the greatest insight into this topic, my team and I mined wisdom from the most esteemed doctors and the foremost experts in nutrition science that have graced the show—individuals who have direct experience with the impacts of a standard American diet, treatment protocols that include lifestyle changes toward plant fuel, the impact, and reversal of serious cardiovascular issues. The full guest list with links to their full episodes is below. Guest list: #678 – Dr. Gemma Newman #664 – Simon Hill #410 – Dr. Dean Ornish #79 – T. Colin Campbell #522 – Dr. Michael Greger #150 – Dr. Garth Davis #507 – Dr. Michael Klaper #492 – Dr. Neal Barnard #140 – Dr. Robert Ostfeld  #589 – Drs. Dean & Ayesha Sherzai #349 – Dr. Joel Kahn #325 – Dr. Kim Williams #541 – Dr. Alan Goldhamer Show notes + MORE Watch on YouTube Newsletter Sign-Up Peace + Plants, Rich

24 Nov 20221h 43min

Whitney Cummings Is Doing The Work

Whitney Cummings Is Doing The Work

Whitney Cummings is a stand-up comedian, writer, actor, producer, and podcaster. You may know her from one of her five hilarious stand-up specials, her sitcom 'Whitney', as the co-creator of the CBS show '2 Broke Girls', or as host of the 'Good For You' podcast. Whitney’s charm and wit is legendary. But underappreciated is her knowledge and experience with mental health and emotional well-being—qualities earned from working through anxiety and and codependency disorders. All of this and more is chronicled in her hilarious and vulnerable book, 'I’m Fine …And Other Lies.' This conversation centers on mental health. We discuss codependency at length—what it is and what it isn’t—building self-esteem, creating confidence, navigating relationships, and healing from childhood trauma. We also talk about animal welfare, equestrian therapy, 12 step recovery, empathy, the importance of forgiveness, and tons more. Whitney is a blast. This episode is epic. I hope you enjoy it! Show notes + MORE Watch on YouTube Newsletter Sign-Up Peace + Plants, Rich

21 Nov 20223h 12min

Tony Riddle's Natural Lifestyle Philosophy For Optimum Health, Happiness & Vitality

Tony Riddle's Natural Lifestyle Philosophy For Optimum Health, Happiness & Vitality

Here to rewild us and reconnect us to that which is most essential is barefoot ultra running phenom Tony Riddle.  Returning for his 2nd appearance on the podcast (his first being over 3 years ago on episode #463), Tony is a natural lifestyle coach who has devoted his life to studying what makes us human and how to live naturally in the modern world. Today we pick things up where we last left off in an old school, no video, audio-only conversation convened during my recent visit to London that goes deeper into Tony's natural lifestyle practices. Tony and I cover his various endurance feats and training, his unique coaching philosophy, and the principles that underscore his new book Be More Human, a bible for deconstructing the ways of living that aren’t serving us, and reconnecting with new ways of living that are more in sync with our human biology. Show notes + MORE: bit.ly/richroll717 Watch on YouTube (audio only) Newsletter Sign-Up: https://www.richroll.com/subscribe This conversation is packed with a battery of actionable practices and strategies to rewild and reboot your life. My hope is that you employ these strategies and they allow you to maximize your human potential. Enjoy! Peace + Plants, Rich

14 Nov 20222h 28min

Roll On: What A Decade of Podcasting Has Taught Me About Life

Roll On: What A Decade of Podcasting Has Taught Me About Life

Welcome to the 2022 season finale of ‘Roll On’, our semi-bi-weekly version of the podcast where we indulge in some good-natured banter and ramble on matters of interest across culture, sports, politics, literature, art, self-betterment, and more. Today Rich and Adam talk endurance news, concerning politics, streaming selects, answer listener questions, and more. Rich also expands on the lessons he’s learned after ten years of podcasting and the wisdom he’s gleaned from some of the brightest minds on the show. Watch on YouTube Show notes + MORE: bit.ly/richroll716 Newsletter Sign-Up: https://www.richroll.com/subscribe Enjoy! Peace + Plants, Rich

10 Nov 20222h 12min

Casey Neistat's Unrelenting Pursuit Of Interestingness

Casey Neistat's Unrelenting Pursuit Of Interestingness

Here today fourth appearance on the podcast—(his last appearance was nearly eight years ago) is the godfather of YouTube, Casey Neistat. One of the biggest and most popular filmmakers on YouTube with over 12.5 million subscribers, Casey rose to fame through a daily vlog he commenced in March of 2015 when he began uploading a new video every single day, elevating the vlog format with next level storytelling & production value that consistently went viral & captured the fascination of millions. In addition to being a friend and occasional running partner, Casey is also an entrepreneur, an angel investor, a husband, a dad, and the director of a new documentary entitled 'Under The Influence', which chronicles the trajectory of a young YouTube creator named David Dobrik from massive popularity to disgrace and the ugly, broader truths of the creator economy that incentivized his demise. Today Casey and I dive deep into what it means to be an artist. We dive into the foundational principles of creativity, filmmaking, and storytelling. We talk about the difference between external versus internal validation and the rewards each brings. If you enjoy our conversation today, check out our earlier exchanges on episodes 73, 144, and 174. Watch: YouTube. Read: Show notes. Enjoy! Peace + Plants, Rich

7 Nov 20221h 29min

The Ant-Viral Gut: Robynne Chutkan, MD On Optimizing Immunity & Preventing Disease From The Inside Out

The Ant-Viral Gut: Robynne Chutkan, MD On Optimizing Immunity & Preventing Disease From The Inside Out

Multiple studies now confirm a dramatic link between the health of our microbiome and our ability to combat viral illness. Today we explore this connection, with tools to promote gut health, optimize your immune system & prevent disease. Our host for today's exploration is the queen of all things gut health, Robynne Chutkan, MD. Dr. Chutkan is a board-certified gastroenterologist serving on the Georgetown University Hospital faculty. She is the founder of the Digestive Center for Wellness, as well as the author of 4 books on the microbiome, including her most recent, The Anti-Viral Gut, which offers practical advice for optimizing diet, exercise, sleep, and time outdoors to boost the body’s defenses and our overall health. Appearing for the 2nd time on the podcast, my initial conversation with Dr. Chutkan 7 years ago (RRP #192) dove into the nuts and bolts of the microbiome: what it is, how it functions, and how we can care for it. Today we zoom in, focusing on the antiviral aspects of gut health, why it’s so important, and what you can do about it. We’ve talked a lot about the microbiome on this podcast, but this exchange is truly a masterclass within itself.  Watch: YouTube. Read: Show notes. I’ve known Robynne for many years—she is such a delightful presence. It was wonderful to have her back in the studio. Her expertise in communicating this subject matter is truly unparalleled, and I am excited to share this one with you. Enjoy! Peace + Plants, Rich

31 Okt 20222h 19min

Gordo Byrn on Making A 1000 Day Plan, Small Promises, The 5:2 Rule, & Designing Your Best Life

Gordo Byrn on Making A 1000 Day Plan, Small Promises, The 5:2 Rule, & Designing Your Best Life

In today’s panoply of role models, rare is the story of an everyman transforming his life wholesale—then sharing his process openly and honestly with humility and vulnerability. Today I convene with one of these aspirational, endurance veteran and personal hero Gordo Byrn. Gordo is someone who greatly inspired and influenced my endurance career and mentored me from afar in ways beyond my ability to calculate. This conversation, long in the making, is thus personally special. A former private equity investment banker, Gordo metamorphosed into an elite ultra-endurance athlete, a student of human performance, an endurance coach, and, mostly, a devoted family man. He’s also the co-author of the endurance bible 'Going Long'—an incredible resource for any and all athletes seeking to better understand and apply the principles of endurance. A Web 1.0 blogger and podcaste, Gordo's humble guidance and wisdom was a consistent presence during my heavy training years, a tradition he continues today on Twitter (@feelthebyrn1)—a platform he uses to share his experience on everything from endurance training to marriage, personal finance and parenting. Meeting Gordo was like meeting a lost twin for the first time, and this conversation was everything I hoped it would be. Watch: YouTube. Read: Show notes. The Swedish superstar and multiple Ultraman and Otillo champion Jonas Colting calls Gordo ‘Tony Robbins in a Speedo.’ I agree with this statement, and after listening to this one, you will too. Peace + Plants, Rich

24 Okt 20222h 43min

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