Rewind Your Clock: David Sinclair, PhD Wants To 'Cure' Aging

Rewind Your Clock: David Sinclair, PhD Wants To 'Cure' Aging

Aging is inevitable. Everybody grows old. Everyone dies. We accept these statements as fact. But what if they're just stories based on history and our current understanding of biology? What if everything we think we know about aging is about to change? Across the globe, scientists are working on treatments and therapies that are designed to extend healthy human lifespans well beyond what we know today. At the bleeding edge of such breakthroughs you will find David Sinclair, PhD, one of the world’s leading scientific authorities on longevity, aging and how to slow its effects. Returning for his second appearance on the podcast, David is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. He obtained his Ph.D. in Molecular Genetics at the University of New South Wales, Sydney in 1995 and worked as a postdoctoral researcher at M.I.T. where, among other things, he co-discovered the cause of aging for yeast. The co-founder of several biotechnology companies, David is also co-founder and co-chief editor of the journal Aging. His work has been featured in a variety of books, documentaries, and media, including 60 Minutes, Nightline and NOVA. He is an inventor on 35 patents, has been lauded as one of the Top 100 Australian Innovators, and made TIME magazine’s list of the 100 most influential people in the world. In addition, David is the author of Lifespan: The Revolutionary Science of Why We Age -- and Why We Don't Have To -- a New York Times bestseller that proposes a radical new theory of aging. As he writes: “Aging is a disease, and that disease is treatable.” Last year I convened my first conversation with David (RRP #436), a scintillating and science-heavy primer on all things human lifespan, aging and longevity. It was a runaway hit with the listeners -- and left me wanting to know more. So today we pick up where we last left off, diving deeper into the physiological mechanisms that contribute to biological degeneration. And we go further into the current state of research to better understand what contributes to aging and what can be done to counteract it. Call him a dreamer, but David believes living to 200+ is a plausible reality. If you could double your lifespan, how would this impact how you choose to live? What would it mean for the future of humanity? And for the ecological stability of the planet? The implications are profound. Equal parts philosophic and scientific, this conversation will forever change the way you think about why you age and what you can do about it. And it will leave you armed simple lifestyle practices you can deploy -- intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat -- that will help you live younger and healthier for longer. Brilliant and lovely, it’s an honor to once again share this man's wisdom with you today. So break out that pen and paper, because you're going to want to take notes on this one. The visually inclined can watch it all go down on YouTube. And as always, the audio version streams wild and free on Apple Podcasts and Spotify. I sincerely hope you enjoy the episode. Peace + Plants, Rich

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The Science Of Happiness: Dr. Laurie Santos Shares Evidence-Based Tools For Genuine Joy, Why We Chase The Wrong Things & What Actually Creates Well-Being

The Science Of Happiness: Dr. Laurie Santos Shares Evidence-Based Tools For Genuine Joy, Why We Chase The Wrong Things & What Actually Creates Well-Being

Dr. Laurie Santos is a renowned psychology professor at Yale University and creator of the most popular course in Yale's history: "Psychology and the Good Life." This conversation explores why our intuitions about happiness are spectacularly wrong and the mental health crisis plaguing young people. We discuss how our brains mislead us about well-being, the power of negative visualization, and evidence-based "rewirements" to overcome our natural biases.  Along the way, she shares the stark reality among elite students and practical strategies for authentic happiness. Laurie brings science to humanity's quest for happiness. Essential for anyone seeking genuine well-being. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up   Today’s Sponsors: Lincoln Financial: Watch The Action Plan series and learn how Lincoln can help you make your pastimes last a lifetime 👉 lincolnfinancial.com/richroll                              On: High-performance shoes & apparel crafted for comfort and style 👉 on.com/richroll AG1: Get a FREE bottle of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉 drinkAG1.com/richroll          Airbnb: Your home might be worth more than you think. Find out how much 👉 airbnb.com/host  WHOOP: The all-new WHOOP 5.0 is here! Get your first month FREE 👉 join.whoop.com/Roll Momentous: 35% OFF your first subscription👉 livemomentous.com/richroll    Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

30 Jun 2h 26min

Ethan Suplee On Shedding 300 Pounds, Ditching Drugs & What It Really Takes To Transform Your Life

Ethan Suplee On Shedding 300 Pounds, Ditching Drugs & What It Really Takes To Transform Your Life

Ethan Suplee is a renowned actor known for My Name is Earl, American History X, and The Wolf of Wall Street. This conversation explores the intersection of trauma, food addiction, and the false narratives of transformation. We discuss Ethan's journey through multiple relapses, the psychology behind sustainable change, and why "diet and exercise" is both completely true and profoundly dishonest. Along the way, Ethan dismantles the mythology of quick fixes and linear progress. Ethan is called to serve. This exchange is incredibly nourishing. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Eight Sleep: Get $350 off your Pod 5 Ultra w/ code RICHROLL👉eightsleep.com/richroll Seed: Use code RICHROLL25 for 25% OFF your first order👉seed.com/RichRoll BetterHelp: Get 10% OFF the first month👉BetterHelp.com/richroll Calm: Get 40% OFF a Calm Premium subscription👉calm.com/richroll  Birch: Get 20% OFF sitewide👉BirchLiving.com/richroll AG1: Get a FREE bottle of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll On: High-performance shoes & apparel crafted for comfort and style 👉on.com/richroll Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

23 Jun 2h 15min

ROLL ON: Embracing Stillness, Recovering From Surgery & Going Slow To Go Slow

ROLL ON: Embracing Stillness, Recovering From Surgery & Going Slow To Go Slow

Roll On returns! Brace yourselves!  Adam Skolnick and I catch up on spinal fusion surgery, going slow to go slow, and what happens when the universe finally gets your attention.  On tap: recovery realizations, walking very slowly, and the wild idea that maybe you're enough without all the doing. We dive into LA's current chaos, maintaining humanity, and why "dear one" isn't as cringy as it sounds.  Last but not least, we explore worthiness, presence, and the art of sitting still when your whole identity is built on movement. Cheers! Show notes + MORE Watch on YouTube Newsletter Sign-Up Momentous: 35% OFF your first subscription👉livemomentous.com/richroll    ON: High-performance shoes & apparel crafted for comfort and style 👉on.com/richroll ROKA: Unlock 20% OFF your order with code RICHROLL👉ROKA.com/RICHROLL Go Brewing: Use the code Rich Roll for 15% OFF 👉gobrewing.com                  Bragg: Get 20% OFF your first order with code RICHROLL👉 Bragg.com        ProLon: Get 15% OFF plus a FREE bonus gift 👉 prolonlife.com/richrollCheck out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

19 Jun 1h 22min

A Skeptic’s Guide To Meditation: Bob Roth On The Science & Extreme Benefits of Transcendental Meditation

A Skeptic’s Guide To Meditation: Bob Roth On The Science & Extreme Benefits of Transcendental Meditation

Bob Roth is one of America's most experienced meditation teachers and executive director of The David Lynch Foundation. This conversation explores the intersection of ancient transcendence and modern necessity. We discuss Bob's 50+ year practice, David Lynch's final words about happiness, the neuroscience of "effortless meditation," and why accessing the fourth state of consciousness isn't a luxury, it's survival technology for the age of AI. He shows how 20 minutes rewires your brain, cuts cortisol by up to 40%, and unlocks "unbounded awareness." Bob democratizes transcendence. This is meditation without the mysticism. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up On: High-performance shoes & apparel crafted for comfort and style 👉on.com/richroll Eight Sleep: Get $350 off your Pod 5 Ultra with code RICHROLL👉eightsleep.com/richroll AG1: ​​Get a FREE bottle of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll                                                                       OneSkin: Get started today with 15% off using code RICHROLL at oneskin.com  Airbnb: Your home might be worth more than you think. Find out how much 👉airbnb.com/host                                                                                     Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

16 Jun 1h 48min

Dr. Matthew Nagra Makes The Ultimate Case For A Plant-Based Diet: Busting Nutrition Myths Around Seed Oils, Soy, Protein, & More

Dr. Matthew Nagra Makes The Ultimate Case For A Plant-Based Diet: Busting Nutrition Myths Around Seed Oils, Soy, Protein, & More

Dr. Matthew Nagra is a Vancouver-based naturopathic doctor and nutrition researcher who tackles misinformation around diet and nutrition on social media. This conversation dismantles nutrition's most malevolent misconceptions—from seed oil hysteria to carnivore evangelism. We explore how tribal allegiances have replaced science, why plant proteins aren't inferior, and the rise of LDL denialism. Matt systematically debunks myths while exposing the cherry-picked studies fueling dietary tribalism. In doing so, he shows us how to distinguish between legitimate research and algorithmic propaganda. Matt is a myth-busting extraordinaire. This exchange cuts straight through the noise. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Seed: Use code RICHROLL25 for 25% OFF your first order 👉seed.com/RichRoll             Go Brewing: Use the code Rich Roll for 15% OFF 👉gobrewing.com Lincoln Financial: New 4-part series "The Action Plan"—exploring what it takes to keep doing what we love, Physically, Mentally & Financially 👉 lincolnfinancial.com/richroll iFit: Use the code RICHROLL to get 10% off any purchase of $999+ 👉NordicTrack.com/richroll            AG1: Get a FREE bottle of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll  Squarespace: Use the code RichRoll to save 10% off your first purchase of a website or domain 👉Squarespace.com/RichRoll    LMNT: Get a free LMNT Sample Pack with any purchase 👉 drinkLMNT.com/richroll                        On: High-performance shoes & apparel crafted for comfort and style 👉on.com/richroll Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

9 Jun 2h 17min

From The Vault: Darin Olien On Fatal Conveniences

From The Vault: Darin Olien On Fatal Conveniences

Darin Olien is a wellness expert and protagonist of Netflix's "Down to Earth" with Zac Efron. This conversation explores the hidden dangers lurking in everyday products we assume are safe, from deodorant and dental floss to clothing and cleaning supplies. We discuss Darin's book "Fatal Conveniences," the toxic chemicals in our environment, why regulation is backwards, and simple swaps to protect your health. Darin also exposes the shocking truths about "forever chemicals" and why your morning routine might be slowly poisoning you. This re-release is more timely than ever. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up On: High-performance shoes & apparel crafted for comfort and style 👉on.com/richroll Momentous: 35% OFF your first subscription👉livemomentous.com/richroll    ROKA: Unlock 20% OFF your order with code RICHROLL👉ROKA.com/RICHROLL Pique: Get up to 20% OFF plus a FREE rechargeable frother and glass beaker with your first purchase 👉piquelife.com/richroll                     PPMP: Use code RICHROLL for $10 off your membership👉mealplanner.richroll.com Modern Elder Academy: Get Chip Conley's NEW book The Midlife Manifesto FREE (just cover shipping) 👉meawisdom.com/manifesto WHOOP: The all-new WHOOP 4.0 is here! Get your first month FREE👉join.whoop.com/Roll Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

5 Jun 2h 17min

Walking As Medicine: Craig Mod’s 300-Miles On Foot, Japan's Philosophy Of Enough,  & The Profound Power Of Undistracted Presence

Walking As Medicine: Craig Mod’s 300-Miles On Foot, Japan's Philosophy Of Enough, & The Profound Power Of Undistracted Presence

Craig Mod is an artist, author, and photographer who has lived in Japan for 25 years, chronicling the country through thousands of miles of recent solo walks. We explore walking as inner cartography—a practice that transforms attention into meaning. We discuss Craig's journey from his best friend's murder in Connecticut to finding home in Tokyo, the ineffable Japanese concept of "yōyū," reconciling adoption trauma through movement, and how 300-mile walks without digital distraction became his path to healing. His story takes a stunning turn when these walks ultimately lead him back to meet his birth mother at 42. Craig transforms heavy into light. And this conversation reveals how. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up On: High-performance shoes & apparel crafted for comfort and style 👉on.com/richroll Bon Charge: Get 15% OFF all my favorite wellness products w/ code RICHROLL 👉 boncharge.com                                                                                          Bragg: Get 20% OFF your first order with code RICHROLL👉 Bragg.com  AG1: Get a FREE bottle of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll Airbnb: Your home might be worth more than you think. Find out how much 👉airbnb.com/host           Squarespace: Use the code RichRoll to save 10% off your first purchase of a website or domain 👉Squarespace.com/RichRoll   Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

2 Jun 2h 48min

Working It Out With Mike Birbiglia: Comedy & Creativity, Podcasting & The Pope

Working It Out With Mike Birbiglia: Comedy & Creativity, Podcasting & The Pope

Mike Birbiglia is a master storyteller, acclaimed comedian, and the creative force behind Netflix specials including "The Old Man & the Pool" and his newest, "The Good Life." This conversation explores the quiet architecture of story—how to shape it, live it, and share it in a way that matters. We talk about finding empathy for the parents who couldn’t fully show up, embracing feedback without losing your voice, and why the creative process might just be as simple and profound as “letting your brain go for a walk.” It’s not about performance. It’s about presence. Mike illuminates our shared humanity. This conversation is medicine for our divided times. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Eight Sleep: Get $350 off your Pod 5 Ultra w/ code RICHROLL👉eightsleep.com/richroll On: High-performance shoes & apparel crafted for comfort and style 👉on.com/richroll Bragg: Get 20% OFF your first order with code RICHROLL👉 Bragg.com BetterHelp: Get 10% OFF the first month👉BetterHelp.com/richroll PPMP: Get $10 OFF your membership with code RICHROLL👉mealplanner.richroll.com ROKA: Unlock 20% OFF your order with code RICHROLL👉ROKA.com/RICHROLL AG1: Get a FREE bottle of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll          Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors   Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

26 Mai 1h 22min

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