Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?
More Plates More Dates13 Feb 2020

Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?

At supraphysiological dosages, taking GH before going to sleep makes sense because there is a negative feedback loop on the growth hormone (GH)/insulin-like growth factor I (IGF-1) axis. In this study, IGF-1 was constantly infused, and the effect on endogenous GH secretion was assessed [R]. Overall, GH concentrations were suppressed during the rhIGF-I infusion by 85±3%, mainly by attenuating spontaneous GH pulse amplitude (77±4% suppression). The apparent GH pulse frequency was attenuated from 7.8±0.9 to 4.7±0.6 pulses/24h (P= 0.006). IGF-1 is the primary feedback, and the mechanism is similar to what you see with the HPTA axis. When there is enough Testosterone and Estrogen, your body has this mechanism in place to prevent you from making more. The same thing happens with exogenous GH use. When you administer exogenous GH, IGF-1 elevates. When your body recognizes that IGF-1 is elevated, it starts to suppress GH pulse amplitude in a dose dependent manner. If you are using supraphysiological amounts of GH for bodybuilding purposes, you can assume that your natural secretion is greatly inhibited during sleep as this negative feedback loop will prevent your body from secreting GH in your sleep like it normally would. When endogenous GH production is suppressed, administering exogenous GH at times that lipolysis or muscle growth can be optimized is the most logical approach to injection timing. https://youtu.be/8j9MGfQPeXg If fat loss is the goal, then taking GH in a fasted state prior to fasted cardio would be ideal. There is a ceiling on how much GH is needed to maximize lipolysis, so if your dosage exceeds 2 IU per day, then I would advise splitting up that dose into two (or more if needed) different periods of the day with as much time between them as possible. If muscle growth is the goal, GH should still be administered in a pulsatile fashion to mimic endogenous secretions. Topped out stimulation of autocrine IGF-1 in skeletal muscle can be achieved with fairly low dosages of exogenous GH, and administering a higher dose above and beyond that may just be a waste. This is why it would be wise to split up your daily GH dose into multiple administrations if you are using supraphysiological dosages. Learn more about your ad choices. Visit megaphone.fm/adchoices

Episoder(1360)

Used Tren At 19 And Became An Angry Cheating Psycho

Used Tren At 19 And Became An Angry Cheating Psycho

📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 👕 Fitness & Lifestyle Clothing: https://bit.ly/4dmGKqW | code "MPMD" for 15% off ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ X: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

20 Jan 21min

The Rock Has Officially Responded To Steroid Allegations

The Rock Has Officially Responded To Steroid Allegations

📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 👕 Fitness & Lifestyle Clothing: https://bit.ly/4dmGKqW | code "MPMD" for 15% off ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ X: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

9 Sep 202540min

The Return Of The King! [Gorilla Mind RUSH]

The Return Of The King! [Gorilla Mind RUSH]

🦍 Dialed in a bottle - https://gorillamind.com/products/gorilla-mind-rush ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 👕 Fitness & Lifestyle Clothing: https://bit.ly/4dmGKqW | code "MPMD" for 15% off ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ X: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

5 Aug 202556min

I Drug Tested Andrew Tate - Natty Or Not?

I Drug Tested Andrew Tate - Natty Or Not?

🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 👕 Fitness & Lifestyle Clothing: https://bit.ly/4dmGKqW | code "MPMD" for 15% off ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ X: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

14 Mai 20252h 16min

This Should Be IMPOSSIBLE - 365lb Man GREW 6 INCHES!? | Brian Sanchez

This Should Be IMPOSSIBLE - 365lb Man GREW 6 INCHES!? | Brian Sanchez

Brian Sanchez, a 365 lb genetic freak who was already 6 feet tall, underwent limb-lengthening surgery to increase his height to 6’6”. For the first time ever he reveals the raw, unfiltered reality of the procedure, the excruciating pain, the grueling recovery, and the mental warfare of reshaping his own body. This is the ultimate deep dive into one of the most extreme body transformations ever attempted. ———————————— 📌 Sponsors: ⚕️ Marek Health - Preventive Medicine, HRT, & Rigorous Bloodwork Analysis: https://bit.ly/373k791 🦍 Gorilla Mind - Pre-Workout, Nootropic, Performance & Health Supporting Formulations: https://gorillamind.com/derek 💡 Intelligent Shop - Hair Loss Prevention, Exclusive Men’s Fragrances & Skin Care: https://intelligent.shop/derek ———————————— Brian’s Social Media: Instagram: https://www.instagram.com/brianthesasquatch/ YouTube: https://www.youtube.com/@brianthesasquatch ———————————— 🕑 Timestamps: 0:00:00 - Intro 0:03:57 - Brian’s Before And After Stats 0:05:48 - Why Brian Got Surgery When He Was Already 6 Feet Tall 0:12:45 - The Reasons Why Most People Get Limb Lengthening Surgery 0:16:20 - The Jack Hanma Story Of Steroid Use And Extreme Limb Lengthening Surgery 0:19:40 - Brian’s First Surgery (Of Many) 0:22:07 - Teens Using Pharmacology To Biohack Getting Taller 0:23:01 - Sponsor: Rigorous Blood Work Analysis With Health And Performance Optimization (Marek Health) 0:28:47 - How Brian Discovered Limb Lengthening Surgery And Convinced Himself To Do It 0:36:14 - How Brian Found A Clinic 0:38:51 - How Is Limb Lengthening Surgery Performed? 0:44:12 - The Max Height You Can Gain Surgically 0:45:58 - Deformed ‘Ballerina Feet’ Claw Syndrome 0:47:47 - Losing Over 100 Pounds To Do The Surgery 0:55:02 - Brian’s Steroid Use 0:55:55 - Sponsor: 4 Staple Supplements I Use Daily And Wish I Had Known About Sooner To Help Maximize My Growth, Recovery, And Health (Gorilla Mind) 1:02:43 - The Price Of Limb Lengthening Surgery 1:11:20 - The Worst Christmas Of Brian’s Life 1:12:58 - The Differences Between Surgery In The US Vs. Turkey (Part 1) 1:17:12 - The History Of Limb Lengthening Surgery 1:20:15 - How Much Can You Trust The Marketing Material Online? 1:26:46 - The Story Of Mr. Broken Bonez 1:33:14 - Brian Maxed Out His Tibias Before Breaking His Femurs 1:34:18 - How Broken Bones Lengthen Mechanistically, And The Risks Of “Non-Union” 1:37:52 - Justifying Femur Surgery Based On Tibia Proportions 1:40:23 - How Long It Takes To Max Out Height From Each Bone 1:43:43 - The Major Complications That Led To Requiring 11 Surgeries 1:52:48 - The Horrific Negligence In The Turkish Hospital 1:58:25 - Sponsor: Hair Loss Prevention, Exclusive Men’s Fragrances & Skin Care (Intelligent Shop) 2:02:17 - How Many People Died Of The 50 Brian Knows Who Had Limb Lengthening Surgery 2:05:26 - The Most Common Complications 2:12:37 - The Differences Between Surgery In The US Vs. Turkey (Part 2) 2:15:24 - The Best Transformations From Limb Lengthening Surgery Brian Is Aware Of 2:24:44 - The Average Height Gain And Recovery Time 2:27:02 - Obstacles Most Don’t Consider Before Getting Limb Lengthening Surgery 2:35:49 - Asking Brian If He Regrets His Decision 2:44:31 - How Dubious Marketing Can Mislead People Into Getting Surgery (Part 1) 2:45:52 - Clinics Overbooking The Amount Of Patients They Can Handle 2:50:25 - Hormone And Diet Optimization For Bone Integrity And Healing 2:53:50 - Brian’s Unrelenting Infection Caused By Surgery 2:57:48 - Is It Possible To Regain 100% Athleticism After Limb Lengthening Surgery? 3:10:37 - The Amount Of Pain Brian Endured From Start To Finish 3:12:56 - Brian’s Leg Size Before And After Surgery 3:13:24 - Brian Showing How Well He Can Walk Now 3:13:44 - Who Is The Ideal Candidate For Limb Lengthening Surgery? 3:17:36 - How Dubious Marketing Can Mislead People Into Getting Surgery (Part 2) 3:19:45 - Brian’s Future Plans ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

17 Feb 20253h 22min

The Real Life Jack Hanma

The Real Life Jack Hanma

📌 From My Full 3+ Hour Conversation With Brian Going Live This Weekend ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

13 Feb 202512min

The Story Of Mr. Broken Bonez - 5′5″ To 6 Feet Tall

The Story Of Mr. Broken Bonez - 5′5″ To 6 Feet Tall

📌 From My Full 3+ Hour Conversation With Brian Going Live This Week. ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

10 Feb 20256min

Steroid Use In The Fitness Industry | ft. Will Tennyson

Steroid Use In The Fitness Industry | ft. Will Tennyson

Will's channel and corresponding video: https://youtu.be/cuE5VHQYZoo?si=AcAU9Qxtqs-l-BS- 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

6 Feb 202519min

Populært innen Fakta

fastlegen
dine-penger-pengeradet
relasjonspodden-med-dora-thorhallsdottir-kjersti-idem
merry-quizmas
treningspodden
foreldreradet
jakt-og-fiskepodden
rss-strid-de-norske-borgerkrigene
dopet
smart-forklart
dypdykk
sovnlos
hverdagspsyken
fryktlos
sinnsyn
gravid-uke-for-uke
diagnose
rss-kunsten-a-leve
rss-kull
podme-bio-3