Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?

Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?

At supraphysiological dosages, taking GH before going to sleep makes sense because there is a negative feedback loop on the growth hormone (GH)/insulin-like growth factor I (IGF-1) axis. In this study, IGF-1 was constantly infused, and the effect on endogenous GH secretion was assessed [R]. Overall, GH concentrations were suppressed during the rhIGF-I infusion by 85±3%, mainly by attenuating spontaneous GH pulse amplitude (77±4% suppression). The apparent GH pulse frequency was attenuated from 7.8±0.9 to 4.7±0.6 pulses/24h (P= 0.006). IGF-1 is the primary feedback, and the mechanism is similar to what you see with the HPTA axis. When there is enough Testosterone and Estrogen, your body has this mechanism in place to prevent you from making more. The same thing happens with exogenous GH use. When you administer exogenous GH, IGF-1 elevates. When your body recognizes that IGF-1 is elevated, it starts to suppress GH pulse amplitude in a dose dependent manner. If you are using supraphysiological amounts of GH for bodybuilding purposes, you can assume that your natural secretion is greatly inhibited during sleep as this negative feedback loop will prevent your body from secreting GH in your sleep like it normally would. When endogenous GH production is suppressed, administering exogenous GH at times that lipolysis or muscle growth can be optimized is the most logical approach to injection timing. https://youtu.be/8j9MGfQPeXg If fat loss is the goal, then taking GH in a fasted state prior to fasted cardio would be ideal. There is a ceiling on how much GH is needed to maximize lipolysis, so if your dosage exceeds 2 IU per day, then I would advise splitting up that dose into two (or more if needed) different periods of the day with as much time between them as possible. If muscle growth is the goal, GH should still be administered in a pulsatile fashion to mimic endogenous secretions. Topped out stimulation of autocrine IGF-1 in skeletal muscle can be achieved with fairly low dosages of exogenous GH, and administering a higher dose above and beyond that may just be a waste. This is why it would be wise to split up your daily GH dose into multiple administrations if you are using supraphysiological dosages. Learn more about your ad choices. Visit megaphone.fm/adchoices

Episoder(1360)

Sustanon TRT Prescription For Only ONE Injection Every THREE WEEKS In Europe!?

Sustanon TRT Prescription For Only ONE Injection Every THREE WEEKS In Europe!?

One of my buddies online Steven, sent me a pamphlet for a European Sustanon prescription. The most baffling thing about this pamphlet is the advised injection frequency at which this Sustanon is prescribed in Europe. I do consultations over Skype through MorePlatesMoreDates.com,… Learn more about your ad choices. Visit megaphone.fm/adchoices

10 Jul 20196min

Chestbrah Hair Loss From Steroids Before And After

Chestbrah Hair Loss From Steroids Before And After

Chestbrah And Zyzz | The Shavershian Brothers Chestbrah (Said Sergeyevich Shavershian) is the brother of Zyzz (Aziz Sergeyevich Shavershian). I'm sure some of you guys know who Zyzz is. He was one of the inspirations I had to start bodybuilding back when I was in high school.… Learn more about your ad choices. Visit megaphone.fm/adchoices

10 Jul 20198min

Using T3 While Bulking To Stay Lean – A Good Or Bad Idea?

Using T3 While Bulking To Stay Lean – A Good Or Bad Idea?

Don't Take T3 If You Aren't Hormonally Deficient There is no point of taking T3 while you're bulking unless you have a deficient thyroid to begin with. Even in that situation, you would also need to verify via blood work that you have an inability to sufficiently convert T4 into T3.… Learn more about your ad choices. Visit megaphone.fm/adchoices

6 Jul 20194min

Could I Have Achieved My Physique With Only TRT Dosages?

Could I Have Achieved My Physique With Only TRT Dosages?

If I could go back in time, could I have achieved my current physique with only TRT dosages? This will depend on a few factors. It's becoming more and more common to see bodybuilders who are transitioning to a more health-conscious approach talk about how they can maintain their physique on very low dosages.… Learn more about your ad choices. Visit megaphone.fm/adchoices

6 Jul 20199min

Should You Use An Oral Steroid During Your Bulk Cycle?

Should You Use An Oral Steroid During Your Bulk Cycle?

“Should you use an oral steroid during your bulk cycle” has been a commonly asked question in the bodybuilding community. It's not a yes or no answer. With that being said, the entire point of this post is to delve into the very common scenario I see guys put themselves in where they actually limit their progress by using additional drugs.… Learn more about your ad choices. Visit megaphone.fm/adchoices

5 Jul 20195min

Can You Maintain Minoxidil Grown Hair After Stopping Minoxidil?

Can You Maintain Minoxidil Grown Hair After Stopping Minoxidil?

A lot of you guys have asked me if you can maintain Minoxidil grown hair after you've stopped using Minoxidil. Can you maintain it with Finasteride, or another hair loss prevention treatment? The harsh reality is that the hairs that you grow via Minoxidil use are 100% dependent on the Minoxidil.… Learn more about your ad choices. Visit megaphone.fm/adchoices

5 Jul 20193min

Does GH (Growth Hormone) Cause Hair Loss? | Androgenic Alopecia Vs Temporary Shedding

Does GH (Growth Hormone) Cause Hair Loss? | Androgenic Alopecia Vs Temporary Shedding

No, growth hormone (GH) cannot cause permanent hair loss. However, it can cause temporary shedding. Let's clarify the difference between androgenic alopecia and temporary shedding. Androgenic alopecia, or male pattern baldness, is the acceleration of hair follicle miniaturization facilitated via androgen receptor activation, which is what most guys experience throughout their lives.… Learn more about your ad choices. Visit megaphone.fm/adchoices

30 Jun 20197min

Trenbolone Dosage For Cattle Vs Humans | WE AREN’T COWS!

Trenbolone Dosage For Cattle Vs Humans | WE AREN’T COWS!

Trenbolone Use In The Bodybuilding Community Trenbolone (commonly referred to as simply “Tren”) is an anabolic androgenic steroid (AAS) that was popularized in the 90's, and has become an increasingly abused drug over the years. Over the years, Trenbolone has evolved into such a commonly used hormone that it is seen by many as “tried and true,” and a necessity to build an amazing physique.… Learn more about your ad choices. Visit megaphone.fm/adchoices

28 Jun 20196min

Populært innen Fakta

fastlegen
dine-penger-pengeradet
relasjonspodden-med-dora-thorhallsdottir-kjersti-idem
merry-quizmas
foreldreradet
treningspodden
dopet
sovnlos
jakt-og-fiskepodden
rss-strid-de-norske-borgerkrigene
hverdagspsyken
fryktlos
dypdykk
sinnsyn
gravid-uke-for-uke
smart-forklart
podme-bio-3
rss-kunsten-a-leve
diagnose
rss-kull