The Effect of Vitamin D on the Epigenome (Folami Ideraabdullah)

The Effect of Vitamin D on the Epigenome (Folami Ideraabdullah)

In this episode of the Epigenetics Podcast, we caught up with Folami Ideraabdullah from the University of Chapel Hill to talk about her work on the environmental modulation of the epigenome during development.

The lab of Folami Ideraabdullah focuses on studying how environmental factors modulate the epigenome. In particular the team investigates how Vitamin D levels influence epigenetic processes and, hence, the susceptibility for diseases like adipositas. Folami Ideraabdullah started with a genome-wide screen of DNA Methylation patterns that are observed after Vitamin D depletion. This work was then followed up by investigating the impact of Vitamin D depletion on mouse sperm DNA methylation.

References

  • Xue, J., Schoenrock, S. A., Valdar, W., Tarantino, L. M., & Ideraabdullah, F. Y. (2016). Maternal vitamin D depletion alters DNA methylation at imprinted loci in multiple generations. Clinical Epigenetics, 8(1), 107. https://doi.org/10.1186/s13148-016-0276-4

  • Xue, J., Gharaibeh, R. Z., Pietryk, E. W., Brouwer, C., Tarantino, L. M., Valdar, W., & Ideraabdullah, F. Y. (2018). Impact of vitamin D depletion during development on mouse sperm DNA methylation. Epigenetics, 13(9), 959–974. https://doi.org/10.1080/15592294.2018.1526027

  • Xue, J., Hutchins, E. K., Elnagheeb, M., Li, Y., Valdar, W., McRitchie, S., Sumner, S., & Ideraabdullah, F. Y. (2020). Maternal Liver Metabolic Response to Chronic Vitamin D Deficiency Is Determined by Mouse Strain Genetic Background. Current Developments in Nutrition, 4(8), nzaa106. https://doi.org/10.1093/cdn/nzaa106

Related Episodes

Contact

Episoder(170)

The Human Cell Atlas (Sarah Teichmann)

The Human Cell Atlas (Sarah Teichmann)

In this episode of the Epigenetics Podcast, we talked with Sarah Teichmann from the University of Cambridge about the Human Cell Atlas. In the Interview we explore Sarah Teichmann's impressive career ...

10 Jul 202546min

The Discovery of Genomic Imprinting (Azim Surani)

The Discovery of Genomic Imprinting (Azim Surani)

In this episode, Professor Asim Surani, shares how his extensive research has significantly advanced the understanding of how the mammalian germline is specified, the mechanisms governing epigenetic r...

19 Jun 202556min

Exploring DNA Methylation and TET Enzymes in Early Development (Petra Hajkova)

Exploring DNA Methylation and TET Enzymes in Early Development (Petra Hajkova)

In this episode of the Epigenetics Podcast, we talked with Petra Hajkova from the MRC Laboratory of Medical Sciences about her work on epigenetics research on mammalian development, highlighting DNA m...

5 Jun 202539min

Epigenetic Regulation and Small Molecule Innovation in AML: Advances in Translational Leukemia Research (Ani Deshpande)

Epigenetic Regulation and Small Molecule Innovation in AML: Advances in Translational Leukemia Research (Ani Deshpande)

In this episode of the Epigenetics Podcast, we talked with Ani Deshpande from Sanford Burnham Prebys about his work on epigenetic regulation and developing small molecules through high throughput scre...

22 Mai 20251h

Beyond Mom: Rethinking Paternal Influence in Epigenetic Inheritance (Raffaele Teperino)

Beyond Mom: Rethinking Paternal Influence in Epigenetic Inheritance (Raffaele Teperino)

In this episode Dr. Raffaele Teperino shares insights from his ongoing research focused on developmental programming, particularly how paternal health before conception influences not only offspring h...

8 Mai 202559min

Evolutionary Epigenetic Clocks and Epigenetic Inheritance in Plants (Frank Johannes)

Evolutionary Epigenetic Clocks and Epigenetic Inheritance in Plants (Frank Johannes)

In this episode of the Epigenetics Podcast, we talked with Dr. Frank Johannes from the Technical University of Munich in Freising about his work on evolutionary clocks and epigenetic inheritance in pl...

24 Apr 202539min

Neuroepigenetic Mechanisms and Primate Epigenome Evolution (Boyan Bonev)

Neuroepigenetic Mechanisms and Primate Epigenome Evolution (Boyan Bonev)

In this episode of the Epigenetics Podcast, we talked with Boyan Bonev from the HelmholtzZetrum in Munich about his work on neuroepigenetics, focusing on gene regulation, chromatin architecture, and p...

10 Apr 202545min

The Role of H3K4me3 in Embryonic Development (Eva Hörmanseder)

The Role of H3K4me3 in Embryonic Development (Eva Hörmanseder)

In this episode of the Epigenetics Podcast, we talked with Dr. Eva Hörmanseder from the HelmholtzZentrum in Munich about her work on epigenetic mechanisms in cellular memory and gene regulation. In th...

27 Mar 202537min

Populært innen Vitenskap

fastlegen
rekommandert
tingenes-tilstand
sinnsyn
forskningno
rss-rekommandert
liberal-halvtime
smart-forklart
jss
tomprat-med-gunnar-tjomlid
villmarksliv
fjellsportpodden
rss-paradigmepodden
dekodet-2
pod-britannia
psykopoden
rss-overskuddsliv
tidlose-historier
aldring-og-helse-podden
nevropodden