Podcast #225: Rhogam

Podcast #225: Rhogam

Author: Dylan Luyten, M.D.

Educational Pearls

  • Rhogam is commonly used when an Rh negative woman has an Rh positive fetus. It is commonly used in the ER in the setting of a miscarriage.
  • Rh(+) fetal blood can enter the Rh(-) maternal circulation, sensitizing the woman to the Rh antigen. During a subsequent pregnancy, if the fetus is Rh(+), the woman may mount an immune response to the fetus, lead to fetal demise. Rhogam is used to block this process.
  • Use of Rhogam has reduced this complication from 16% of Rh(+) pregnancies in the 1960's to less than 1% today.
  • Under 10 weeks, the amount of maternal-fetal blood exchange is very small, so the use of Rhogam in a 1st trimester miscarriage is unnecessary. It should be used in patients with a miscarriage after 12 weeks, or women undergoing a surgical D&C.
  • Rhogam is expensive and in limited supply, so it is important to only use it when necessary.

References: Hannafin, Blaine et al. Do Rh-negative women with first trimester spontaneous abortions need Rh immune globulin? 2006. The American Journal of Emergency Medicine, Volume 24 , Issue 4 , 487 - 489

Episoder(1147)

Pharmacy Phriday #11: Riddles, Medical Jargon, NNT, and Time Travel

Pharmacy Phriday #11: Riddles, Medical Jargon, NNT, and Time Travel

Contributors: Kali Olson PharmD, Travis Barlock MD, Jeffrey Olson MS2 Summary: In this episode of Pharmacy Phriday, Dr. Kali Olson joins Dr. Travis Barlock and Jeffrey Olson in studio to discuss a var...

23 Feb 202443min

Episode 891: Hypothermia

Episode 891: Hypothermia

Contributor: Taylor Lynch MD Educational Pearls Hypothermia is defined as a core body temperature less than 35 degrees Celsius or less than 95 degrees Fahrenheit  Mild Hypothermia: 32-35 degrees C...

19 Feb 20244min

Podcast 890: Outdoor Cold Air for Croup

Podcast 890: Outdoor Cold Air for Croup

Contributor: Jared Scott MD Educational Pearls: Croup is a respiratory condition typically caused by a viral infection (e.g., parainfluenza). The disease is characterized by inflammation of the lary...

14 Feb 20244min

Podcast 889: Blood Pressure Cuff Size

Podcast 889: Blood Pressure Cuff Size

Contributor: Aaron Lessen MD Educational Pearls: Does the size of a blood pressure (BP) cuff matter? A recent randomized crossover trial revealed that, indeed, cuff size can affect blood pressure read...

5 Feb 20241min

Podcast 888: Low GCS and Intubation

Podcast 888: Low GCS and Intubation

Contributor: Aaron Lessen MD Educational Pearls: Is the adage, "GCS of 8, you've got to intubate" accurate? A recent study published in the November 2023 issue of JAMA attempted to answer this questio...

29 Jan 20242min

Podcast 887: Family Presence in Cardiac Resuscitation

Podcast 887: Family Presence in Cardiac Resuscitation

Contributor: Aaron Lessen MD Educational Pearls: A 2013 study randomized families of those in cardiac arrest into two groups: Actively offered patients' families the opportunity to observe CPR ...

22 Jan 20242min

Podcast 886: Cough in Kids

Podcast 886: Cough in Kids

Contributor: Ricky Dhaliwal, MD Educational Pearls: Croup Caused by: Parainfluenza, Adenovirus, RSV, Enterovirus (big right now) Age range: 6 months to 3 years Symptoms: Barky cough ...

15 Jan 20246min

Podcast 885: Penetrating Neck Injuries

Podcast 885: Penetrating Neck Injuries

Contributor: Ricky Dhaliwal MD Educational Pearls: Three zones of the neck with different structures and risks for injuries: Zone 1 is the most caudal region from the clavicle to the cricoid cart...

10 Jan 20244min

Populært innen Vitenskap

fastlegen
tingenes-tilstand
rekommandert
jss
liberal-halvtime
rss-rekommandert
sinnsyn
forskningno
villmarksliv
rss-paradigmepodden
fjellsportpodden
dekodet-2
pod-britannia
rss-overskuddsliv
tidlose-historier
hva-er-greia-med
tomprat-med-gunnar-tjomlid
katastrofe-i-hjernen
rss-lundqvist-podden
rss-nysgjerrige-norge