Podcast #262: Pertussis

Podcast #262: Pertussis

Author: Julian Orenstein, M.D.

Educational Pearls

  • Colorado has a high population of unvaccinated children, and is at increased risk for pertussis outbreaks.
  • The causative organism is Bordetella pertussis. It causes causes respiratory epithelial necrosis leading to congestion of the bronchioles, leading to cough.
  • The cough is unique - it is usually a series of expiratory coughs followed by one deep inspiration
  • The clinical presentation is divided into 3 phases:
    • Catarrhal: cough and congestion with low-grade fever and coryza.
    • Whooping: characteristic cough.
    • Resolution: recovery with persistent cough.
  • Infants may not get this presentation, but may get apnea and nonspecific cough.
  • Tongue depressor can be used to elicit cough for diagnosis.

References: Tozzi AE, Pastore Celentano L, Ciofi degli Atti ML, Salmaso S. Diagnosis and management of pertussis. CMAJ : Canadian Medical Association Journal. 2005;172(4):509-515. doi:10.1503/cmaj.1040766.

Episoder(1145)

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Author: Rachael Duncan, PharmD BCPS BCCCP Topic: Rachel explains the science behind one of the most common maladies thought to be induced by chronic cannabis use.

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Podcast #224: Troponin

Podcast #224: Troponin

Author: Sam Killian, M.D. Educational Pearls Not every troponin elevation is an MI. Trop elevates in about an hour in ACS and stays elevated for days. Non-MI conditions that cause elevated troponin: ...

1 Jul 20174min

Podcast #223: Acyclovir Toxicity

Podcast #223: Acyclovir Toxicity

Author: Nick Hatch, M.D. Educational Pearls Acyclovir toxicity can uncommonly cause altered mental status, low blood glucose, hallucinations and myoclonic jerks. Toxicity often occurs in the setting ...

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Podcast #222: Wells Criteria for PE

Podcast #222: Wells Criteria for PE

Author: Michael Hunt, M.D. Educational Pearls Wells Criteria was initially designed to screen patients for further workup for PE. Aspects of the Wells Criteria include: signs and symptoms of DVT (3...

27 Jun 20174min

Podcast #221: Walking Corpse Syndrome

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Podcast #221: Walking Corpse Syndrome Author: Erik Verzemnieks, M.D. Educational Pearls Walking Corpse Syndrome (aka Cotard Delusion) is a very rare psychiatric disorder that leads to the belief that...

25 Jun 20171min

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