Podcast #276: Angioedema

Podcast #276: Angioedema

Author: John Winkler, M.D.

Educational Pearls

  • Angioedema is immediately life-threatening due to airway obstruction.
  • Mechanisms include allergic reaction (histamine-related) or bradykinin-related (ACE-inhibitor, C1 esterase inhibitor deficiency).
  • The bradykinin-related mechanism will not respond to the traditional meds used for anaphylaxis. Instead, use FFP to replace depleted factors.
  • If a patient displays signs of respiratory compromise, intubation is indicated. Anesthesia should be consulted as this will be a very difficult airway.

References: https://emcrit.org/pulmcrit/treatment-of-acei-induced-angioedema/

Episoder(1145)

Podcast # 366: Ehlers Danlos

Podcast # 366: Ehlers Danlos

Podcast # 366: Ehlers Danlos Author: Gretchen Hinson, MD. Educational Pearls: Heritable mutation in collagen synthesis and expression commonly resulting in joint hyperextension and skin elasticity....

15 Aug 20184min

Podcast # 365: Renal Trigger Point Injections

Podcast # 365: Renal Trigger Point Injections

Author: Erik Verzemnieks, MD Educational Pearls: Single study in Japan demonstrated possible effectiveness of renal colic trigger point Patients had injection at the area of maximal tenderness on...

13 Aug 20181min

Podcast # 364: Other causes of ST elevation

Podcast # 364: Other causes of ST elevation

Author: Peter Bakes, MD Educational Pearls: Pericarditis, LBBB, LVH and left ventricular aneurysms can all present with ST elevation. Ventricular aneurysm will present days after a cardiac event ...

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Podcast # 363:  Ketamine for Alcohol Withdrawal

Podcast # 363: Ketamine for Alcohol Withdrawal

Educational Pearls: Recent study has shown adjunctive ketamine can be useful in setting of alcohol withdrawal. Ketamine was associated with a decrease in the amount of benzodiazepines needed, lik...

8 Aug 20182min

Podcast # 362: Giant Hogweed

Podcast # 362: Giant Hogweed

Author: John Winkler, MD Educational Pearls: Tall flowering plant with phototoxic sap Direct skin contact with the sap can cause the skin to become photosensitive Severe blisters and even burns...

6 Aug 20182min

Podcast # 361: Vertiginous Dizziness

Podcast # 361: Vertiginous Dizziness

Author: Peter Bakes, MD Educational Pearls: Important to find out if patients mean dysequilibrium, lightheadedness, or vertigo when patients say they are "dizzy." Differentiate central vs. periph...

3 Aug 20186min

Podcast # 360: Epidural Abscess Screening

Podcast # 360: Epidural Abscess Screening

Author: Dylan Luyten, MD. Educational Pearls:   Dangerous causes of back pain: AAA, cauda equina syndrome, epidural abscess. Young person with back pain needs to be evaluated for injection drug use...

2 Aug 20184min

Podcast # 359: Normal EKG

Podcast # 359: Normal EKG

Author: Sam Killian, MD. Educational Pearls: Computer interpretation has a very good negative predictive value of a normal EKG (99%). Of 222 interpreted as "normal," 13 were deemed to have some a...

31 Jul 20184min

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