Podcast #322: Methemoglobinemia

Podcast #322: Methemoglobinemia

Author: Nick Hatch, M.D.

Educational Pearls:

  • Methemoglobinemia is when the iron in hemoglobin is in the Fe3+ (ferric) state rather than the normal Fe2+ (ferrous) state. Methemoglobin cannot release oxygen at the tissues.
  • Symptoms include cyanosis, headache, tachycardia, dyspnea, and lethargy.
  • Suspect in setting of hypoxia that does not improve with oxygenation, and clinical cyanosis with a normal PaO2 on ABG.
  • Treatment is methylene blue which reduces the iron back to the ferrous state.
  • Causes can be Dapsone, Lidocaine, Benzocaine.

References:

Agarwal N, Nagel RL, Prchal JT. Dyshemoglobinemias. In: Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management, 2nd ed, Steinberg M (Ed), 2009. P.607

Cortazzo JA, Lichtman AD. (2014). Methemoglobinemia: a review and recommendations for management. Journal of Cardiothoracic and Vascular Anesthesia. 28:1043.

Darling R, Roughton F. (1942). The effect of methemoglobin on the equilibrium between oxygen and hemoglobin. American Journal of Physiology. 137:56.

Episoder(1147)

Podcast 622: High Altitude Pulmonary Edema (HAPE)

Podcast 622: High Altitude Pulmonary Edema (HAPE)

Contributor: Thomas Seibert, MD Educational Pearls: High Altitude Pulmonary Edema (HAPE) typically occurs 2-4 days after arriving at elevation Symptoms include: Fatigue Dyspnea Cough Treatment in...

15 Des 20204min

Podcast 621: Pediatric Psychosis

Podcast 621: Pediatric Psychosis

Contributor: Aaron Lessen, MD Educational Pearls: Schizophrenia typically doesn't present until age 13 and has a prodrome Prodrome includes months of gradual changes in behavior, starting with negati...

14 Des 20203min

Pharmacy Phriday #5: COVID-19 Vaccine for Pregnant Women

Pharmacy Phriday #5: COVID-19 Vaccine for Pregnant Women

Contributors: Rachael Duncan, PharmD and Sean McCullough, PharmD Educational Pearls: A 2019 Report by the National Women's Law Center: Most common occupations for pregnant workers are elementary and ...

11 Des 202019min

Podcast 620: Prolactin and Seizures

Podcast 620: Prolactin and Seizures

Contributor: Aaron Lessen, MD Educational Pearls: Serum prolactin levels can be used to help differentiate epileptic seizures from non-epileptic seizures It is also released and elevated after epilep...

8 Des 20203min

Podcast 619: Other Uses for Zyprexa

Podcast 619: Other Uses for Zyprexa

Contributor: Don Stader, MD Educational Pearls: Zyprexa (olanzapine) is a second generation antipsychotic with multiple other uses Excellent for treating nausea in patients undergoing chemotherapy or...

7 Des 20204min

Podcast 618: Treating Opiate Side Effects

Podcast 618: Treating Opiate Side Effects

Contributor: Don Stader, MD Educational Pearls: Majority of patients experience side effects while taking opioids Most common include nausea/vomiting, puriitis, constipation; more severe and less com...

1 Des 20204min

Podcast 617: Masks and Understanding Data

Podcast 617: Masks and Understanding Data

Contributor: Peter Bakes, MD Educational Pearls: Recent study looked at if mask wearing protects the mask wearer from infection This group found 1.8% of mask wearers got COVID while 2.1% of non-mask ...

30 Nov 20204min

Pharmacy Phriday #4: mRNA Vaccines

Pharmacy Phriday #4: mRNA Vaccines

Contributor: Rachael Duncan, PharmD Educational Pearls: ED visits nationwide declined by 42% in April 2020 compared to the same time in 2019 largely due to the fear of the COVID-19 pandemic. The big...

27 Nov 202016min

Populært innen Vitenskap

fastlegen
rekommandert
tingenes-tilstand
jss
rss-rekommandert
liberal-halvtime
villmarksliv
rss-paradigmepodden
forskningno
sinnsyn
fjellsportpodden
pod-britannia
rss-nysgjerrige-norge
tidlose-historier
hva-er-greia-med
rss-lundqvist-podden
dekodet-2
tomprat-med-gunnar-tjomlid
vett-og-vitenskap-med-gaute-einevoll
nordnorsk-historie