Podcast 551:  PPIs are Not Benign

Podcast 551: PPIs are Not Benign

Contributor: Don Stader, MD

Educational Pearls:

  • PPIs (Proton pump inhibitors) reduce stomach acid levels and are commonly prescribed in patients with GERD or peptic ulcer disease
  • Stopping a PPI after sustained use for a month or longer can lead to withdrawal - causing a rebound indigestion or reflux due to a surge in acid production
  • Long term PPI use has noteworthy side effects including increased incidence of bacterial GI infections and pneumonia
  • Be cautious in prescribing a PPI for over 2 weeks. If continued indigestion control is needed, transition to a H2 blocker or OTC antacids if prolonged treatment is needed.

References

1)Haastrup PF, Thompson W, Søndergaard J, Jarbøl DE (2018) Side effects of long-term proton pump inhibitor use: a review. Basic Clin Pharmacol Toxicol 123(2):114–121. https://doi.org/10.1111/bcpt.13023 Review

2) Helgadottir, H.; Bjornsson, E.S. Problems Associated with Deprescribing of Proton Pump Inhibitors. Int. J. Mol. Sci. 2019, 20, 5469.

Summarized by Jackson Roos, MS3 | Edited by Erik Verzemnieks, MD



Episoder(1147)

Podcast 525:  Enjoyable Epistaxis?

Podcast 525: Enjoyable Epistaxis?

Contributor: Jared Scott, MD Educational Pearls: The ED is full of painful procedures. One of the most commonly dreaded procedures is nasal packing for epistaxis, as it is quite uncomfortable for the...

24 Des 20193min

Podcast 524:  Bacterial Endocarditis

Podcast 524: Bacterial Endocarditis

Contributor: Sue Chilton, MD Educational Pearls: More intracardiac devices and injection drug abuse are thought to be increasing incidence of endocarditis Classic signs of endocarditis have included:...

20 Des 20193min

Podcast 523:  A Dizzying Diagnosis

Podcast 523: A Dizzying Diagnosis

Contributor: Don Stader, MD Educational Pearls: It can be difficult to distinguish between central and peripheral causes of vertigo. Cerebellar stroke should be considered with any dizzy patient.  Si...

17 Des 20192min

UnfilterED #3: Dr. Katie Bakes & Dr. Pete Bakes

UnfilterED #3: Dr. Katie Bakes & Dr. Pete Bakes

Husband and wife Pete and Katie Bakes, both emergency physicians in the Denver-Metro area, reflect on their upbringings, the many lessons learned over their twenty year careers, and how they've evolve...

14 Des 20191h 43min

Podcast 522: e-Cigarette and Vaping Related Lung Injury

Podcast 522: e-Cigarette and Vaping Related Lung Injury

Contributor: John Winkler, MD Educational Pearls: Vaping-related lung injury initially presents with flu-like symptoms and can progress to respiratory failure requiring aggressive resuscitation inclu...

10 Des 20192min

Podcast 521: Traumatic Hyphema

Podcast 521: Traumatic Hyphema

Author: Jared Scott, MD Educational Pearls: A hyphema is blood in the anterior chamber of the eye, typically caused by trauma While there is a spectrum of disease, blurred vision and eye pain are com...

5 Des 20192min

Podcast 520:  Approach to the arresting patient

Podcast 520: Approach to the arresting patient

Contributor: Peter Bakes, MD Educational Pearls: Peri-arrest patients present a particular challenge to ED providers, as the differential is broad and time is critical  The differential for near card...

3 Des 20197min

CBHW Summit: The Cycle of Drug-Related Stigma - Implications for the Opioid Crisis

CBHW Summit: The Cycle of Drug-Related Stigma - Implications for the Opioid Crisis

From DU's 1st annual Colorado Behavioral Health and Wellness Summit: Contributor: Michael Miller, Strategic Initiatives Coordinator, Jefferson County Public Health

27 Nov 201956min

Populært innen Vitenskap

fastlegen
tingenes-tilstand
rekommandert
jss
liberal-halvtime
rss-rekommandert
rss-paradigmepodden
villmarksliv
sinnsyn
forskningno
pod-britannia
dekodet-2
fjellsportpodden
rss-overskuddsliv
tidlose-historier
rss-lundqvist-podden
hva-er-greia-med
rss-nysgjerrige-norge
tomprat-med-gunnar-tjomlid
noen-har-snakket-sammen