Podcast 593: TXA for GIB

Podcast 593: TXA for GIB

Contributor: Ricky Dhaliwal, MD, JD

Educational Pearls:

  • Tranexamic acid (TXA) as shown to have mortality benefit to patients with traumatic GI hemorrhage but should it be used to achieve hemostasis in atraumatic GI bleeding?
  • HALT-IT study looked at TXA for the treatment of upper and lower GI hemorrhage and found no 5 day mortality benefit
  • Patients given TXA also had higher occurrences of DVT and PE

References

Roberts I, Coats T, Edwards P, et al. HALT-IT--tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial. Trials. 2014;15:450. Published 2014 Nov 19. doi:10.1186/1745-6215-15-450

Summarized by Jackson Roos, MS4 | Edited by Erik Verzemnieks, MD



Episoder(1145)

Podcast 774: Maggots

Podcast 774: Maggots

Contributor: Chris Holmes, MD Educational Pearls: Maggots were discovered as a therapy to help wound healing in WWI, but this fell out of favor after the discovery of penicillin One study from Israel...

19 Apr 20225min

Podcast 773: Atrial Fibrillation Medications

Podcast 773: Atrial Fibrillation Medications

Contributor: Aaron Lessen, MD Educational Pearls: Atrial fibrillation is an irregular heart rhythm that sometimes requires rate control in setting of rapid ventricular response (RVR) Calcium channel ...

18 Apr 20223min

Podcast 772: Firearms in Suicidal Ideation

Podcast 772: Firearms in Suicidal Ideation

Contributor: Aaron Lessen, MD Educational Pearls: Firearms are a dangerous potential method of committing suicide Death occurs in about 5-15% of suicide attempts overall, but death in suicide attempt...

12 Apr 20224min

Podcast 771: Intubation in Cardiac Arrest

Podcast 771: Intubation in Cardiac Arrest

Contributor: Don Stader, MD Educational Pearls: In a secondary analysis of the PART trial, the mortality effect of timing of airway management for patients in cardiac arrest was examined Study looked...

11 Apr 20223min

Podcast 770: Xylazine

Podcast 770: Xylazine

Contributor: Don Stader, MD Educational Pearls: Xylazine, referred to as tranq dope colloquially, is an FDA approved animal tranquilizer that is circulating in the illicit drug markets of the northea...

5 Apr 20223min

Podcast 769: Pressors After Cardiac Arrest

Podcast 769: Pressors After Cardiac Arrest

Contributor: Aaron Lessen, MD Educational Pearls: Hypotension after cardiac arrest often requires a vasopressor to improve blood pressure Recent observational study from France examined outcomes of p...

4 Apr 20223min

Mental Health Monthly #11: De-escalation: Changing Confrontation to Collaboration

Mental Health Monthly #11: De-escalation: Changing Confrontation to Collaboration

Contributor: Dr. Kimberly Nordstrom De-escalation usually takes less time than physical and chemical restraints, which leads to decreased injury to staff members, better patient trust and increased p...

30 Mar 202216min

Podcast 768: Takotsubo Cardiomyopathy

Podcast 768: Takotsubo Cardiomyopathy

Contributor: Peter Bakes, MD Educational Pearls: 3% of cases of acute coronary syndrome are due to Takotsubo Takotsubo cardiomyopathy or "broken heart syndrome" can occur with severe physiologic or ...

29 Mar 20224min

Populært innen Vitenskap

fastlegen
tingenes-tilstand
rekommandert
jss
rss-rekommandert
rss-nysgjerrige-norge
villmarksliv
forskningno
sinnsyn
rss-paradigmepodden
fjellsportpodden
vett-og-vitenskap-med-gaute-einevoll
nordnorsk-historie
smart-forklart
rss-overskuddsliv
diagnose
abid-nadia-skyld-og-skam
abels-tarn
tomprat-med-gunnar-tjomlid
aldring-og-helse-podden