Podcast 668: Opioid-Induced Hyperalgesia

Podcast 668: Opioid-Induced Hyperalgesia

Contributor: Donald Stader, MD

Educational Pearls:

  • Opioids target kappa and NMDA receptors that can lead to central nervous system sensitization and therefore increased pain
  • For patients with opioid-induced hyperalgesia (OIH), oral ketamine (25-50 mg) can be used to treat their pain as it targets the NMDA receptor
  • Other treatments is IV magnesium, NSAIDs, tylenol, and clonidine
  • Buprenorphine and methadone are options for chronic pain management in the setting of OIH

References

Lee M, Silverman SM, Hansen H, Patel VB, Manchikanti L. A comprehensive review of opioid-induced hyperalgesia. Pain Physician. 2011;14(2):145-161.

Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD

The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at www.emergencymedicalminute.com/cme-courses/ and create an account.

Donate to EMM today!



Episoder(1145)

Deep Dive #6: Bacteriuria and the Elderly

Deep Dive #6: Bacteriuria and the Elderly

Author: Heidi Wald, MD, MSPH Associate Professor of Medicine - University of Colorado School of Medicine, Physician Advisor - Colorado Hospital Association Dr. Heidi Wald explains common misconceptio...

25 Sep 201729min

Podcast #255: Posterior Vitreous Detachment

Podcast #255: Posterior Vitreous Detachment

Author: Erik Verzemnieks, M.D. Educational Pearls Posterior vitreous detachment is the tearing of the lining in the back of of the eye. Patients often present with loss of vision and floaters. Diagno...

22 Sep 20171min

Podcast #254: Myths About Antibiotic Course Length

Podcast #254: Myths About Antibiotic Course Length

Author: Chris Holmes, M.D. Educational Pearls There's little/no data about the necessary length of an antibiotic course, nor has it proven that stopping a course of antibiotics early selects for the ...

20 Sep 20174min

Podcast #253: Total Eclipse of the Eye - Solar Retinopathy

Podcast #253: Total Eclipse of the Eye - Solar Retinopathy

Author: Nick Hatch, M.D. Educational Pearls Photic or solar retinitis occurs when you stare at the sun. The refractive power of the lens of the eye concentrates the light of the sun on the retina, st...

18 Sep 20173min

Podcast #252: Mandible Fractures

Podcast #252: Mandible Fractures

Author: Sam Killian, M.D. Educational Pearls The tongue blade test is done for mandible fractures, which make up 40-60% of facial fractures. The test is done by having the patient bite down on a tong...

15 Sep 20174min

Podcast #251: Cyanide Poisoning

Podcast #251: Cyanide Poisoning

Author: Rachel Beham, PharmD, Advanced Clinical Pharmacist – Emergency Medicine Educational Pearls Cyanide poisoning is suspected in patients who present with lactic acidosis after being trapped arou...

13 Sep 20174min

Podcast #250: Desmopressin

Podcast #250: Desmopressin

Author: Rachael Duncan, PharmD BCPS BCCCP Educational Pearls Desmopressin is an ADH mimetic and helps retain water, release von Willibrand Factor (in high doses), and treat diabetes insipidus (in low...

11 Sep 20173min

Podcast #249: Detecting Pulses

Podcast #249: Detecting Pulses

Author: Jared Scott, M.D. Educational Pearls Overall, medical providers are bad at detecting pulses. However, only 2% of patients do not have a detectable DP pulse. In one study, for patients with l...

10 Sep 20173min

Populært innen Vitenskap

fastlegen
tingenes-tilstand
rekommandert
jss
rss-nysgjerrige-norge
rss-rekommandert
vett-og-vitenskap-med-gaute-einevoll
sinnsyn
forskningno
villmarksliv
nordnorsk-historie
fjellsportpodden
rss-paradigmepodden
smart-forklart
rss-overskuddsliv
aldring-og-helse-podden
diagnose
pod-britannia
tomprat-med-gunnar-tjomlid
tidlose-historier