Podcast 691: TXA in Head Bleeds

Podcast 691: TXA in Head Bleeds

Contributor: Ricky Dhaliwal, MD

Educational Pearls:

  • CRASH 3 Trial looked at over 12,000 patients with traumatic intracranial bleeds, randomizing patients to a therapy with TXA or standard of care without TXA
  • Dosing was 1 gram over 10 min for loading dose and then an infusion of 1 gram over 8 hours
  • Found Improvement in survival and neurologic outcomes when patient received TXA within 3 hours

References

CRASH-3 trial collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial [published correction appears in Lancet. 2019 Nov 9;394(10210):1712]. Lancet. 2019;394(10210):1713-1723. doi:10.1016/S0140-6736(19)32233-0

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Episoder(1145)

Podcast 869: Shift Work

Podcast 869: Shift Work

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Episode 868: Airway Management in Obesity

Episode 868: Airway Management in Obesity

Contributor: Aaron Lessen MD Educational Pearls: Why is airway management more difficult in obesity? Larger body habitus causes the chest to be above the head when the patient is lying supine, creat...

11 Sep 20233min

Episode 867: Occult Scaphoid Fractures

Episode 867: Occult Scaphoid Fractures

Contributor: Nick Tsipis MD Educational Pearls: The scaphoid bone is the most proximal carpal bone just distal to the radius Fractures of the scaphoid bone are sometimes missed by plain X-rays ...

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Podcast 866: Carbamazepine (Tegretol) Overdose

Podcast 866: Carbamazepine (Tegretol) Overdose

Contributor: Aaron Lessen MD Educational Pearls: What is Carbamazepine (Tegretol)? Carbamazepine is an anti-epileptic drug with mood-stabilizing properties that is used to treat bipolar disorder, ep...

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Laboring Under Pressure- Episode 1. ACLS in Pregnancy with Dr. Jason Papazian

Laboring Under Pressure- Episode 1. ACLS in Pregnancy with Dr. Jason Papazian

Contributor: Jason Papazian MD, Travis Barlock MD, Jeffrey Olson Summary: In this episode, Dr. Travis Barlock and Jeffrey Olson meet in the studio to discuss several clips from Dr. Jason Papazian's ta...

24 Aug 202332min

Podcast 865: Nausea Treatments - Droperidol vs Ondansetron RCT

Podcast 865: Nausea Treatments - Droperidol vs Ondansetron RCT

Contributor: Aaron Lessen MD Educational Pearls: A recent randomized controlled trial compared ondansetron 8 mg IV with droperidol 2.5 mg IV for the treatment of nausea & vomiting in the emergency d...

21 Aug 20232min

Podcast 864: Arterial Blood Gas (ABG) vs Venous Blood Gas (VBG)

Podcast 864: Arterial Blood Gas (ABG) vs Venous Blood Gas (VBG)

Contributor: Aaron Lessen MD Educational Pearls: What is measured in an ABG/VBG? Blood values for oxygen tension (pO2), carbon dioxide tension (pCO2), acidity (pH), oxyhemoglobin saturation, and bic...

14 Aug 20232min

Podcast 863: Treatments for Alcohol Use Disorder

Podcast 863: Treatments for Alcohol Use Disorder

Contributor: Aaron Lessen MD Educational Pearls: Patients with alcohol use disorder are frequently discharged from the ED without further resources Pharmacological treatments to reduce cravings in...

7 Aug 20232min

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