Podcast 691: TXA in Head Bleeds

Podcast 691: TXA in Head Bleeds

Contributor: Ricky Dhaliwal, MD

Educational Pearls:

  • CRASH 3 Trial looked at over 12,000 patients with traumatic intracranial bleeds, randomizing patients to a therapy with TXA or standard of care without TXA
  • Dosing was 1 gram over 10 min for loading dose and then an infusion of 1 gram over 8 hours
  • Found Improvement in survival and neurologic outcomes when patient received TXA within 3 hours

References

CRASH-3 trial collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial [published correction appears in Lancet. 2019 Nov 9;394(10210):1712]. Lancet. 2019;394(10210):1713-1723. doi:10.1016/S0140-6736(19)32233-0

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Episoder(1145)

Podcast 826: STEMI Equivalents

Podcast 826: STEMI Equivalents

Contributor: Travis Barlock, MD Educational Pearls: The presence of a STEMI has traditionally been used to determine if a patient with acute chest pain requires urgent cath lab management STEMI indi...

1 Nov 20224min

Podcast 825: ALS vs PD Transport

Podcast 825: ALS vs PD Transport

Contributor: Aaron Lessen, MD Educational Pearls: In urban settings, it is becoming more common for police to transport critical patients from scene to hospital A 2022 multicenter observational study...

31 Okt 20222min

Podcast 824: Catheter-Related Blood Infections

Podcast 824: Catheter-Related Blood Infections

Contributor: Travis Barlock, MD Educational Pearls: Catheter related blood infections were thought to be caused by skin flora seeding the catheter. Thus, significant effort is applied to sterility an...

25 Okt 20223min

Podcast 823: Immediate Resuscitative Thoracotomy

Podcast 823: Immediate Resuscitative Thoracotomy

Contributor: Jared Scott, MD Educational Pearls: Immediate resuscitative thoracotomy can be performed in the ED to gain rapid access to the thoracic cavity in cases of traumatic cardiac arrest Wester...

24 Okt 20227min

Podcast 822: Meralgia Paresthetica

Podcast 822: Meralgia Paresthetica

Contributor: Aaron Lessen, MD Educational Pearls: Lateral Cutaneous Femoral Nerve Entrapment Syndrome, also known as Meralgia Paresthetica, results from entrapment of the lateral cutaneous femoral ne...

18 Okt 20223min

Podcast 821: EKGs in Syncope

Podcast 821: EKGs in Syncope

Contributor: Travis Barlock, MD Educational Pearls: An EKG should be obtained quickly after a syncopal event to identify possible life-threatening causes such as ischemia and arrhythmia WOBBLER is a...

17 Okt 20224min

Podcast 820: Who Qualifies for Take-Home Naloxone

Podcast 820: Who Qualifies for Take-Home Naloxone

Contributor: Don Stader, MD Educational Pearls: Home naloxone is traditionally given to those at high risk for opioid overdose such as those in the ED due to an opioid overdose, opioid intoxication, ...

11 Okt 20224min

Podcast 819: Indiscriminate Lactate Testing

Podcast 819: Indiscriminate Lactate Testing

Contributor: Jared Scott, MD Educational Pearls: Elevated lactate levels can be a useful indicator of critical illness in patients who meet SIRS criteria Lactate can also be elevated due to ot...

10 Okt 20225min

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