Emergency Medical Minute8 Nov 2021

Podcast 727: Antibiotics for Diverticulitis

Contributor: Aaron Lessen, MD

Educational Pearls:

Classically, diverticulitis is diagnosed via CT scan and patients are discharged home on antibiotics if they are without complication
The DINAMO study is a multicenter open-label RCT that evaluated if it is safe to not give antibiotics to patients with mild acute diverticulitis
Found no difference in readmission, return visits to ED, pain control, or likelihood of surgical intervention between the group that was sent home with antibiotics and the group without
Medical societies have not reached a consensus on this issue, likely further studies need to be completed

References

Mora-López L, Ruiz-Edo N, Estrada-Ferrer O, et al. Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-label, Noninferiority Trial. Ann Surg. 2021;274(5):e435-e442. doi:10.1097/SLA.0000000000005031

*Image from Hellerhoff, CC BY-SA 3.0 <https://creativecommons.org/licenses/by-sa/3.0>, via Wikimedia Commons

Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD

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