Emergency Medical Minute6 Feb 2023

Podcast 847: ECMO CPR

Contributor: Aaron Lessen, MD

Educational Pearls:

Extracorporeal Membrane Oxygenation (ECMO) has been attempted as an adjunct to CPR during cardiac arrest but few studies on outcomes exist
One prior small study stopped early when it showed ECMO with CPR (ECPR) was significantly superior to CPR
Recent large, multicenter randomized control study in Netherlands evaluated neurologic outcomes in CPR versus ECPR

At 30 days and 6 months no significant difference between the groups was found

More studies are required determine if certain patients may benefit from ECPR

References

Belohlavek J, Smalcova J, Rob D, et al. Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial. JAMA. 2022;327(8):737-747. doi:10.1001/jama.2022.1025

Suverein MM, Delnoij TSR, Lorusso R, et al. Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest. N Engl J Med. 2023;388(4):299-309. doi:10.1056/NEJMoa2204511

Summarized by Kirsten Hughes, MS4 | Edited by John Spartz, MD, & Erik Verzemnieks, MD

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