Episode 913: Vasopressors after ROSC

Episode 913: Vasopressors after ROSC

Contributor: Travis Barlock MD

Educational Pearls:

  • Recent study assessed outcomes after ROSC with epinephrine vs. norepinephrine

    • Observational multicenter study from 2011-2018

    • 285 patients received epineprhine and 481 received norepinephrine

  • Epinephrine was associated with an increase in all-cause mortality (primary outcome)

    • Odds ratio 2.6; 95%CI 1.4-4.7; P = 0.002

    • Higher cardiovascular mortality (secondary outcome)

    • Higher proportion of unfavorable neurological outcome (secondary outcome)

  • Norepinephrine is the vasopressor of choice in post-cardiac arrest care

References

  1. Bougouin W, Slimani K, Renaudier M, et al. Epinephrine versus norepinephrine in cardiac arrest patients with post-resuscitation shock. Intensive Care Med. 2022;48(3):300-310. doi:10.1007/s00134-021-06608-7

Summarized by Jorge Chalit, OMSIII | Edited by Meg Joyce & Jorge Chalit

Episoder(1150)

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Episode 971: Calcium Pretreatment for Diltiazem in AFib with RVR

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Episode 970: Fever Management

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Contributor: Aaron Lessen, MD Educational Pearls: Recorded March 2025 What is the best treatment for a fever? Tylenol? Ibuprofen? Combined? Alternating the two? The journal Pediatrics aimed to answer...

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Episode 969: Shoulder Reduction

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Episode 968: Heavy Metals

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Contributor: Megan Hurley MD Educational Pearls: Acute toxicity of heavy metals: Gastrointestinal upset is the most common presentation Chronic toxicity of heavy metals: Symptoms depend on the meta...

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Episode 967: Dilutional Hyponatremia

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Contributor: Taylor Lynch, MD Educational Pearls: Dilutional Hyponatremia: Occurs when there is an excess of free water relative to sodium in the body. Causes a falsely low sodium concentration witho...

28 Jul 20252min

EMSAC 2024

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Contributors: Col. (Dr.) Stacy Shackelford Dr. Sean Keenan Paramedic Alan Moreland Dr. Chris Tems Kara Napolitano From military-inspired trauma protocols to behavioral health alternatives and cardiac ...

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Episode 966: Acetaminophen Toxicity

Episode 966: Acetaminophen Toxicity

Contributor: Jorge Chalit-Hernandez, OMS4 Educational Pearls: What is the toxic dose of acetaminophen? 7.5 grams, in an adult. The safe daily limit is 4 grams in an adult with a normally functioning...

21 Jul 20253min

Episode 965: Oxygen Administration in Trauma Patients

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Contributor: Aaron Lessen, MD Educational Pearls: Many trauma patients are placed on oxygen via non-rebreather A large, multicenter, controlled trial evaluated the outcomes of oxygen administration i...

14 Jul 20252min

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