Episode 913: Vasopressors after ROSC

Episode 913: Vasopressors after ROSC

Contributor: Travis Barlock MD

Educational Pearls:

  • Recent study assessed outcomes after ROSC with epinephrine vs. norepinephrine

    • Observational multicenter study from 2011-2018

    • 285 patients received epineprhine and 481 received norepinephrine

  • Epinephrine was associated with an increase in all-cause mortality (primary outcome)

    • Odds ratio 2.6; 95%CI 1.4-4.7; P = 0.002

    • Higher cardiovascular mortality (secondary outcome)

    • Higher proportion of unfavorable neurological outcome (secondary outcome)

  • Norepinephrine is the vasopressor of choice in post-cardiac arrest care

References

  1. Bougouin W, Slimani K, Renaudier M, et al. Epinephrine versus norepinephrine in cardiac arrest patients with post-resuscitation shock. Intensive Care Med. 2022;48(3):300-310. doi:10.1007/s00134-021-06608-7

Summarized by Jorge Chalit, OMSIII | Edited by Meg Joyce & Jorge Chalit

Episoder(1144)

Episode 934: Subendocardial Ischemia

Episode 934: Subendocardial Ischemia

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Contributor: Alec Coston MD Educational Pearls: Causes of seizures in a fairly well-appearing child with diarrhea: Electrolyte abnormalities: hypocalcemia, hyponatremia Also hyperkalemia which...

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Episode 932: Induction Agent Hypotension

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Contributor: Aaron Lessen MD Educational Pearls: Induction agent selection during rapid sequence intubation involves accounting for hemodynamic stability in the post-intubation setting Many emerge...

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Episode 931: Naloxone in Cardiac Arrest

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Contributor: Aaron Lessen MD Educational Pearls: Can opioids cause cardiac arrest? Opioids can cause respiratory suppression and the subsequent low oxygen levels can lead to arrhythmias and eventual...

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Episode 930: Holding Costs

Episode 930: Holding Costs

Contributor: Aaron Lessen MD Educational Pearls: A study evaluated the patient-care impact and financial costs of holding patients in the ED, a nationwide issue Prospective, observational study o...

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Episode 929: Traumatic Aortic Injury

Episode 929: Traumatic Aortic Injury

Contributor: Aaron Lessen MD Educational Pearls: Aortic injury occurs in 1.5-2% of patients who sustain blunt thoracic trauma Majority are caused by automobile collisions or motorcycle accidents ...

4 Nov 20245min

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Laboring Under Pressure Episode 4: Obstetric Emergency in South Africa with Dr. Meghan Hurley Contributors: Meghan Hurley MD, Travis Barlock MD, Jeffrey Olson MS3 Show Pearls Map of South Africa Refer...

31 Okt 202427min

Episode 928: Neutropenic Fever

Episode 928: Neutropenic Fever

Contributor: Taylor Lynch, MD Educational Pearls: What is neutropenic fever? Specific type of fever that is seen in cancer patients and other patients with impaired immune systems These patients a...

28 Okt 20245min

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