Surrogate Clinical Outcomes and Expanded Endpoints: point/counterpoint.
In this episode, we explore the evolving role of surrogate clinical outcomes and expanded endpoints in heart failure research, featuring a point/counterpoint discussion that examines different perspec...
9 Sep 20min
How to leverage natural history cohorts for regulatory purposes?
In this episode, host Dr. Christopher O'Connor sits down with Drs. Barry Greenberg, Marvin Konstam, and Jim Carr to discuss how to leverage natural history cohorts for regulatory purposes.
19 Aug 31min
The Stories Behind the People with Dr. Robert Califf
In this inaugural episode of The Stories Behind the People, host Dr. Christopher O'Connor sits down with Dr. Robert Califf for a candid conversation that goes beyond medicine. Together, they explore D...
13 Aug 14min
CKM Score
In this episode, host Dr. Christopher O'Connor is joined by Dr. Carine Hamo, Dr. Ankeet Bhatt, and Dr. Javed Butler to discuss the CKM Score and the quantitative methods that are beginning to transfor...
22 Jul 18min
Evaluating and Accounting for Body Weight and Obesity / Adjusting for Body Weight
In this episode, host Dr. Christopher O'Connor is joined by Drs. Carine Hamo, Ankeet Bhatt, Joan Lindenfeld, and Martin Cowie to discuss the importance of evaluating and accounting for body weight and...
1 Jul 28min
Derisking Phase II Clinical Trials in HF
In this episode, host Christopher O'Connor sits down with Scott D. Solomon, Ellis Unger, Janet Wittes, Michael Felker, Ben Saville, Douglas Mann, and Fady Malik to discuss how to design Phase II clini...
10 Jun 32min
Class Effect considerations in devices
In this episode, Host Dr. Christopher O'Connor and his guests, Dr, Joann Lindenfeld, Dr. Mitchell Psotka, Dr. Minnow Walsh and Dr. William Abraham, discuss class effect considerations in devices.
20 Mai 17min
Crossover designs and event driven trials in devices
In this episode, host Christopher O’Connor and his colleagues discuss device trials and how they differ from drug trials. The conversation focuses on how device trials can be improved and how to advan...
29 Apr 28min
