101 | David Baltimore on the Mysteries of Viruses

101 | David Baltimore on the Mysteries of Viruses

I recently saw an estimate that if you took all the novel coronaviruses in the world (the actual viruses, not patients), you could fit them into a bucket no more than a couple of liters in volume. A huge impact has been wrought by a very small amount of stuff. The world of viruses is vast and complicated, and we're still learning some of its basic features. Today's guest David Baltimore won the Nobel Prize in Physiology or Medicine for the discovery that genetic information in viruses could flow from RNA to DNA, establishing an exception to the Central Dogma of Biology. He is the author of the Baltimore Classification scheme for viruses, and has done important research in the role of viruses in diseases from AIDS to cancer. We talk about what viruses are, how they work, and the status of the novel coronavirus we are currently battling. David also has some strong opinions about public health and how we should be preparing for future outbreaks.

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David Baltimore received his Ph.D. in molecular biology from the Rockefeller Institute. He is currently the Robert Andrews Millikan Professor of Biology at Caltech. At age 37 he was awarded the Nobel Prize, which he shared with Howard Temin and Renato Dulbecco. He has served as the President of both Rockefeller University and Caltech, as well as President of the American Association for the Advancement of Science and the Founding Director of the Whitehead Institute for Biomedical Research. Among his other awards are the National Medal of Science and the Warren Alpert Foundation Prize.


Episoder(419)

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10 | Megan Rosenbloom on the Death Positive Movement

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9 | Solo -- Why Is There Something Rather than Nothing?

9 | Solo -- Why Is There Something Rather than Nothing?

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13 Aug 20181h 21min

8 | Carl Zimmer on Heredity, DNA, and Editing Genes

8 | Carl Zimmer on Heredity, DNA, and Editing Genes

Our understanding of heredity and genetics is improving at blinding speed. It was only in the year 2000 that scientists obtained the first rough map of the human genome: 3 billion base pairs of DNA wi...

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7 | Yascha Mounk on Threats to Liberal Democracy

7 | Yascha Mounk on Threats to Liberal Democracy

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30 Jul 20181h 5min

6 | Liv Boeree on Poker, Aliens, and Thinking in Probabilities

6 | Liv Boeree on Poker, Aliens, and Thinking in Probabilities

Poker, like life, is a game of incomplete information. To do well in such a game, we have to think in terms of probabilities, unpredictable strategies, and Bayesian inference. These are ideas that pla...

23 Jul 20181h 10min

5 | Geoffrey West on Networks, Scaling, and the Pace of Life

5 | Geoffrey West on Networks, Scaling, and the Pace of Life

If you scale up an animal to twice its height, keeping everything else proportionate, its volume and weight become eight times as much. Such a scaling relation was used by J.B.S. Haldane in his famous...

16 Jul 20181h 23min

4 |  Anthony Pinn on Humanism, Theology, and the Black Community

4 | Anthony Pinn on Humanism, Theology, and the Black Community

According to atheism, God does not exist. But religions have traditionally done much more than simply proclaim God's existence: they have provided communities, promoted the arts, handed down moral gui...

12 Jul 20181h

3 | Alice Dreger on Sexuality, Truth, and Justice

3 | Alice Dreger on Sexuality, Truth, and Justice

The human mind loves nothing more than to build mental boxes -- categories -- and put things into them, then refuse to accept it when something doesn't fit. Nowhere is this more clear than in the idea...

11 Jul 20181h 20min

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