112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

Not too long ago nobody carried a mobile phone; now almost everybody does. That's the kind of rate of rapid progress we're seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term "gene editing." We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.

Support Mindscape on Patreon.

Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.

Todays episode is sponsored by The Great Courses Plus. Mindscape listeners get a free trial if they sign up at http://thegreatcoursesplus.com/mindscape.

Episoder(419)

AMA | June 2023

AMA | June 2023

Welcome to the June 2023 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreo...

5 Jun 20232h 58min

238 | Scott Shapiro on the Technology and Philosophy of Hacking

238 | Scott Shapiro on the Technology and Philosophy of Hacking

Modern computers are somewhat more secure against being hacked - either by an inanimate virus or a human interloper - than they used to be. But as our lives are increasingly intertwined with computers...

29 Mai 20231h 27min

237 | Brooke Harrington on Offshore Wealth as a Complex System

237 | Brooke Harrington on Offshore Wealth as a Complex System

The modern world is large and interconnected, and there are a lot of systems that might be important to how it functions but about which most people are barely aware. One of these is the offshore weal...

22 Mai 20231h 18min

236 | Thomas Hertog on Quantum Cosmology and Hawking's Final Theory

236 | Thomas Hertog on Quantum Cosmology and Hawking's Final Theory

Is there a multiverse, and if so, how should we think of ourselves within it? In many modern cosmological models, the universe includes more than one realm, with possibly different laws of physics, an...

15 Mai 20231h 8min

AMA | May 2023

AMA | May 2023

Welcome to the May 2023 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreon...

8 Mai 20233h 8min

235 | Andy Clark on the Extended and Predictive Mind

235 | Andy Clark on the Extended and Predictive Mind

What is the mind, and what does it try to do? An overly simplified materialist view might be that the mind emerges from physical processes in the brain. But you can be a materialist and still recogniz...

1 Mai 20231h 21min

234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played b...

24 Apr 20231h 6min

233 | Hugo Mercier on Reasoning and Skepticism

233 | Hugo Mercier on Reasoning and Skepticism

Here at the Mindscape Podcast, we are firmly pro-reason. But what does that mean, fundamentally and in practice? How did humanity come into the idea of not just doing things, but doing things for reas...

17 Apr 20231h 12min

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