112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

Not too long ago nobody carried a mobile phone; now almost everybody does. That's the kind of rate of rapid progress we're seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term "gene editing." We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.

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Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.

Todays episode is sponsored by The Great Courses Plus. Mindscape listeners get a free trial if they sign up at http://thegreatcoursesplus.com/mindscape.

Episoder(423)

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37 | Edward Watts on the End of the Roman Republic and Lessons for Democracy

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36 | David Albert on Quantum Measurement and the Problems with Many-Worlds

36 | David Albert on Quantum Measurement and the Problems with Many-Worlds

Quantum mechanics is our best theory of how reality works at a fundamental level, yet physicists still can't agree on what the theory actually says. At the heart of the puzzle is the "measurement prob...

4 Mar 20191h 42min

35 | Jessica Yellin on The Changing Ways We Get Our News

35 | Jessica Yellin on The Changing Ways We Get Our News

Everything we think about the world outside our immediate senses is shaped by information brought to us by other sources. In the case of what's currently happening to the human race, we call that info...

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34 | Paul Bloom on Empathy, Rationality, Morality, and Cruelty

34 | Paul Bloom on Empathy, Rationality, Morality, and Cruelty

Within every person's mind there is on ongoing battle between reason and emotion. It's not always a battle, of course; very often the two can work together. But at other times, our emotions push us to...

18 Feb 20191h 10min

33 | James Ladyman on Reality, Metaphysics, and Complexity

33 | James Ladyman on Reality, Metaphysics, and Complexity

Reality is a tricky thing. Is love real? What about the number 5? This is clearly a job for a philosopher, and James Ladyman is one of the world's acknowledged experts. He and his collaborators have b...

11 Feb 20191h 7min

32 | Naomi Oreskes on Climate Change and the Distortion of Scientific Facts

32 | Naomi Oreskes on Climate Change and the Distortion of Scientific Facts

Our climate is in the midst of dramatic changes, driven largely by human activity, with potentially enormous consequences for humanity and other species. That's why science tells us, anyway. But there...

4 Feb 20191h 10min

31 | Brian Greene on the Multiverse, Inflation, and the String Theory Landscape

31 | Brian Greene on the Multiverse, Inflation, and the String Theory Landscape

String theory was originally proposed as a relatively modest attempt to explain some features of strongly-interacting particles, but before too long developed into an ambitious attempt to unite all th...

28 Jan 20191h 11min

30 | Derek Leben on Ethics for Robots and Artificial Intelligences

30 | Derek Leben on Ethics for Robots and Artificial Intelligences

It's hardly news that computers are exerting ever more influence over our lives. And we're beginning to see the first glimmers of some kind of artificial intelligence: computer programs have become mu...

21 Jan 20191h 28min

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