117 | Sean B. Carroll on Randomness and the Course of Evolution

117 | Sean B. Carroll on Randomness and the Course of Evolution

Evolution is a messy business, involving as it does selection pressures, mutations, genetic drift, and the effects of random external interventions. So in the end, how much of it is predictable, and how much is in the hands of chance? Today we're thrilled to have as a guest my evil (but more respectable, by most measures) twin, the biologist Sean B. Carroll. Sean is both a leader of the modern evo-devo revolution, and a wonderful and diverse writer. We talk about the importance of randomness and unpredictability in life, from the evolution of species to the daily routine of every individual.

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Sean B. Carroll received a Ph.D. in immunology from Tufts University. He is currently the Andrew and Mary Balo and Nicholas and Susan Simon Endowed Chair of Biology at the University of Maryland, Vice-President for Science Education at the Howard Hughes Medical Institute, the Executive Director of HHMI Tangled Bank Studios, and Professor Emeritus of Genetics and Molecular Biology at the University of Wisconsin. His new book, A Series of Fortunate Events: Chance and the Making of the Planet, Life, and You, explores the role of chance in the development of life.


Episoder(415)

Holiday Message 2025 | The Romance of the University

Holiday Message 2025 | The Romance of the University

Time for the holiday message! Rounding off the year with a brief and casual reflection on some issue that doesn't quite rise to the level of a full solo podcast. And hopefully something uplifting. Thi...

22 Des 202542min

AMA | December 2025

AMA | December 2025

Welcome to the December 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

15 Des 20253h 36min

338 | Ryan Patterson on the Physics of Neutrinos

338 | Ryan Patterson on the Physics of Neutrinos

The story goes that Wolfgang Pauli, who first proposed the existence of neutrinos, was embarrassed to have done so, as it was considered uncouth to hypothesize new particles that could not be detected...

8 Des 20251h 26min

337 | Kevin Zollman on Game Theory, Signals, and Meaning

337 | Kevin Zollman on Game Theory, Signals, and Meaning

Game theory is a way of quantitatively describing what happens any time one thing interacts with another thing, when both things have goals and potential rewards. That's a pretty broad class of intere...

1 Des 20251h 17min

336 | Anil Ananthaswamy on the Mathematics of Neural Nets and AI

336 | Anil Ananthaswamy on the Mathematics of Neural Nets and AI

Machine learning using neural networks has led to a remarkable leap forward in artificial intelligence, and the technological and social ramifications have been discussed at great length. To understan...

24 Nov 20251h 14min

AMA | November 2025

AMA | November 2025

Welcome to the November 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

17 Nov 20253h 34min

335 | Andrew Jaffe on Models, Probability, and the Universe

335 | Andrew Jaffe on Models, Probability, and the Universe

Science has an incredibly impressive track record of uncovering nonintuitive ideas about the universe that turn out to be surprisingly accurate. It can be tempting to think of scientific discoveries a...

10 Nov 20251h 17min

334 | Daniel Whiteson on the Physics of and by Aliens

334 | Daniel Whiteson on the Physics of and by Aliens

The universe as revealed by physics is objective: it's out there, existing and behaving in ways that are completely independent of human thought. But the process by which we learn about the universe, ...

3 Nov 20251h 14min

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