117 | Sean B. Carroll on Randomness and the Course of Evolution

117 | Sean B. Carroll on Randomness and the Course of Evolution

Evolution is a messy business, involving as it does selection pressures, mutations, genetic drift, and the effects of random external interventions. So in the end, how much of it is predictable, and how much is in the hands of chance? Today we're thrilled to have as a guest my evil (but more respectable, by most measures) twin, the biologist Sean B. Carroll. Sean is both a leader of the modern evo-devo revolution, and a wonderful and diverse writer. We talk about the importance of randomness and unpredictability in life, from the evolution of species to the daily routine of every individual.

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Sean B. Carroll received a Ph.D. in immunology from Tufts University. He is currently the Andrew and Mary Balo and Nicholas and Susan Simon Endowed Chair of Biology at the University of Maryland, Vice-President for Science Education at the Howard Hughes Medical Institute, the Executive Director of HHMI Tangled Bank Studios, and Professor Emeritus of Genetics and Molecular Biology at the University of Wisconsin. His new book, A Series of Fortunate Events: Chance and the Making of the Planet, Life, and You, explores the role of chance in the development of life.


Episoder(415)

333 | Gordon Pennycook on Unthinkingness, Conspiracies, and What to Do About Them

333 | Gordon Pennycook on Unthinkingness, Conspiracies, and What to Do About Them

Why are people wrong all the time, anyway? Is it because we human beings are too good at being irrational, using our biases and motivated reasoning to convince ourselves of something that isn't quite ...

27 Okt 20251h 10min

332 | Dmitri Tymoczko on the Mathematics Behind Music

332 | Dmitri Tymoczko on the Mathematics Behind Music

Music is math that you can dance to. The fact that certain notes sound good when played together, or in succession, is related to the mathematical properties of the frequencies to which they correspon...

20 Okt 20251h 21min

AMA | October 2025

AMA | October 2025

Welcome to the October 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pat...

13 Okt 20253h 37min

331 | Solo: Fine-Tuning, God, and the Multiverse

331 | Solo: Fine-Tuning, God, and the Multiverse

Certain features of our universe seem unnatural to us. These include "constants of nature" such as the cosmological constant and the mass of the Higgs boson, as well as features of the initial conditi...

6 Okt 20251h 54min

330 | Petter Törnberg on the Dynamics of (Mis)Information

330 | Petter Törnberg on the Dynamics of (Mis)Information

A characteristic of complex systems is that individual components combine to exhibit large-scale emergent behavior even when the components were not specifically designed for any particular purpose wi...

29 Sep 20251h 12min

329 | Steven Pinker on Rationality and Common Knowledge

329 | Steven Pinker on Rationality and Common Knowledge

Getting along in society requires that we mostly adhere to certainly shared norms and customs. Often it's not enough that we all know what the rules are, but also that everyone else knows the rules, a...

22 Sep 20251h 16min

328 | Mary Roach on Replacing Parts of Our Bodies

328 | Mary Roach on Replacing Parts of Our Bodies

Like any machine, bodies occasionally break down, and it's natural to go in search of a replacement part. Ancient societies featured simple prosthetics for teeth, noses, and limbs, while modern medici...

15 Sep 20251h 7min

AMA | September 2025

AMA | September 2025

Welcome to the September 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by P...

8 Sep 20253h 30min

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