100 | Solo | Life and Its Meaning

A podcast only hits the century mark once! And for Mindscape, this is it. There have been holiday messages and bonus episodes and the like. But this is the 100th officially-numbered episode. To celebrate, I decided to treat myself to a solo episode in which I reflect, somewhat non-systematically, on the age-old question of the meaning of life. I end up spending a lot (most?) of the time talking about the meaning of "life," i.e. what it means to be a living organism in a naturalistic universe. But then I go on to muse about the construction of human meaning in a world where values are not imposed on us or objectively grounded in physical facts.

I think life does have meaning, and it's important to understand what forms it might take. I settle largely on the idea that humans can conceive of different possible futures, assign value to them, and work against the natural order of things to create something that otherwise would not have been. This is far from the final word, even in my own mind; it's an invitation to think and converse in a reasonable way about some of the biggest questions there are. Just like the podcast in general.

Support Mindscape on Patreon.

Here are some modern works offering other perspectives on the meaning of life:

Episoder(418)

AMA | June 2025

AMA | June 2025

Welcome to the June 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreo...

2 Jun 20253h 23min

316 | Niayesh Afshordi and Phil Halper

316 | Niayesh Afshordi and Phil Halper

Einstein's general theory of relativity, plus some reasonable assumptions about the universe and what it's made of, has a remarkable implication: that as we trace cosmic evolution into the far past, w...

26 Mai 20251h 28min

315 | Branden Fitelson on the Logic and Use of Probability

315 | Branden Fitelson on the Logic and Use of Probability

Every time you see an apple spontaneously break away from a tree, it falls downward. You therefore claim that there is a law of physics: apples fall downward from trees. But how can you really know? A...

19 Mai 20251h 28min

314 | Karen Lloyd on the Deep Underground Biosphere

314 | Karen Lloyd on the Deep Underground Biosphere

There are living creatures dwelling deep below the surface of the Earth, as deep as we are able to drill. These hearty microorganisms are related to more familiar life forms on land and under water, b...

12 Mai 20251h 9min

313 | Eric Topol on the Changing Face of Medicine and Aging

313 | Eric Topol on the Changing Face of Medicine and Aging

Medical science is advancing at an astonishing rate. Today we talk with leading expert Eric Topol about two aspects of this story. First, the use of artificial intelligence in medicine, especially in ...

5 Mai 20251h 12min

AMA | May 2025

AMA | May 2025

Welcome to the May 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreon...

28 Apr 20253h 38min

312 | Thomas Levenson on the Mutual History of Humans and Germs

312 | Thomas Levenson on the Mutual History of Humans and Germs

The germ theory of disease is a crowning achievement of science, up there with modern physics, continental drift, and evolution via natural selection. (Even if there will always be cranky skeptics.) B...

21 Apr 20251h 31min

311 | Annaka Harris on Whether Consciousness is Fundamental

311 | Annaka Harris on Whether Consciousness is Fundamental

Questions about consciousness range from the precise and empirical -- what neurons fire when I have some particular experience -- to the deeply profound -- does consciousness emerge from matter, or do...

14 Apr 20251h 10min

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