8 | Carl Zimmer on Heredity, DNA, and Editing Genes

The future grows out of the present, but it manages to consistently surprise us. How can we get better at anticipating and preparing for what the future can be like? Jane McGonigal started out as a game designer, working on the kinds of games that represent miniature worlds with their own rules. This paradigm provides a useful way of thinking about predicting the future: imagining changes in the current world, then gaming out the consequence, allowing real people to produce unexpected emergent outcomes. We talk about the lessons learned that anyone can use to better prepare their brain for the future to come.Support Mindscape on Patreon.Jane McGonigal received her Ph.D. in performance studies from the University of California, Berkeley. She is currently a writer and Director of Games Research and Development at the Institute for the Future. She teaches a course at Stanford on How to Think Like a Futurist. She has developed several games, including SuperBetter, a game she designed to improve health and resilience after suffering from a concussion. Her recent book is Imaginable: How to See the Future Coming and Feel Ready for Anything–Even Things That Seem Impossible Today.Web siteInstitute for the Future pageUrgent OptimistsAmazon.com author pageWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Apr 20221h 21min

Biological organisms are pretty good at healing themselves, but their abilities fall short in crucial ways. Planaria can be cut into pieces, and each piece will regrow into an entire organism; but for most advanced animals, loss of a limb becomes a permanent condition. But why should that necessarily be so, if an organism’s genome knows what it’s supposed to look like? Lea Goentoro’s lab has recently produced surprising results that indicate that it’s easier than you might think to coax animals into regenerating limbs.Support Mindscape on Patreon.Lea Goentoro received her Ph.D. in chemical engineering from Princeton University. She is currently Professor of Biology at Caltech. Her research involves how biological systems function and develop across a variety of scales, including perception, organization, and self-repair.Lab web pageCaltech web pageGoogle Scholar publications“A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice“See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Mar 20221h 3min

All societies grant more power to some citizens, and there is always a temptation to use that power for the benefit of themselves rather than for the greater good. Power corrupts, we are told — but to what extent is that true? Would any of us, upon receiving great power, be tempted by corruption? Or are corruptible people drawn to accrue power? Brian Klaas has investigated these questions by looking at historical examples and by interviewing hundreds of people who have been in this position. He concludes that power can corrupt, but it doesn’t necessarily do so — we can construct safeguards to keep corruption to a minimum.Support Mindscape on Patreon.Brian Klaas received his D.Phil. in Politics from the University of Oxford. He is currently Associate Professor in Global Politics at University College London and a columnist for The Washington Post. His new book is Corruptible: Who Gets Power and How it Changes Us. He is host of the Power Corrupts podcast.Web siteUCL web pageWashington Post columnsWikipediaAmazon author pageTwitterNew Zealand Police recruitment videoSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

21 Mar 20221h 22min

Welcome to the March 2022 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). I take the large number of questions asked by Patreons, whittle them down to a more manageable size — based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good — and sometimes group them together if they are about a similar topic. Enjoy!Support Mindscape on Patreon.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Mar 20223h 18min

If extraterrestrial life is out there — not just microbial slime, but big, complex, macroscopic organisms — what will they be like? Movies have trained us to think that they won’t be that different at all; they’ll even drink and play music at the same cafes that humans frequent. A bit of imagination, however, makes us wonder whether they won’t be completely alien — we have zero data about what extraterrestrial biology could be like, so it makes sense to keep an open mind. Arik Kershenbaum argues for a judicious middle ground. He points to constraints from physics and chemistry, as well as the tendency of evolution to converge toward successful designs, as reasons to think that biologically complex aliens won’t be utterly different from us after all.Support Mindscape on Patreon.Arik Kershenbaum received his Ph.D. in Evolutionary Biology and Ecology from the University of Haifa. He is currently College Lecturer and Director of Studies at Girton College, University of Cambridge. He is the author of The Zoologist’s Guide to the Galaxy: What Animals on Earth Reveal About Aliens — and Ourselves.Web siteCambridge web pageGoogle Scholar publicationsAmazon author pageTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

14 Mar 20221h 21min

We’re pretty well-calibrated when it comes to dealing with common, everyday-level setbacks. But our brains aren’t naturally equipped for dealing with unlikely but world-catastrophic disasters. Yet such threats are real, both natural and human-induced. We need to collectively get better at anticipating and preparing for them, at the level of political action. Andrew Leigh is an academic and author who now serves in the Parliament of Australia. We discuss how to move the conversation about existential risks from the ivory tower to implementation in real policies.Support Mindscape on Patreon.Andrew Leigh received his Ph.D. in Public Policy from the Kennedy School of Government at Harvard University. He is a member of the Australian House of Representatives representing Fenner. He was previously a professor of economics at Australian National University, and has served as Shadow Assistant Minister for Treasury and Charities. His recent book is What’s the Worst That Could Happen? Existential Risk and Extreme Politics.Web siteResearch web siteWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

7 Mar 20221h 20min

Advances in technology have gradually been extending the human self beyond its biological extent, as we augment who we are with a variety of interconnected devices. There are obvious benefits to this — it lets us text our friends, listen to podcasts, and not get lost in strange cities. But as it changes how we interact with other people, it’s important to consider the possible downsides. Sherry Turkle is a psychologist and writer who specializes in the relationship between humans and their technology. She makes the case for not forgetting about empathy, conversation, and even the occasional imperfection in how we present ourselves to the world.Support Mindscape on Patreon.Sherry Turkle received her Ph.D. in sociology and personality psychology from Harvard University. She is currently Abby Rockefeller Mauzé Professor of the Social Studies of Science and Technology in the Program in Science, Technology, and Society at MIT, founding director of the MIT Initiative on Technology and Self, and a licensed clinical psychologist. Among her awards are a Guggenheim Fellowship, a Rockefeller Humanities Fellowship, the Harvard Centennial Medal, and she was named “Woman of the Year” by Ms. Magazine. Her new book is The Empathy Diaries: A Memoir.Web siteMIT web pageWikipediaAmazon author pageTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Feb 20221h 11min

One of the brilliant achievements of Darwin’s theory of natural selection was to help explain apparently “purposeful” or “designed” aspects of biology in a purely mechanistic theory of unguided evolution. Features are good if they help organisms survive. But should we put organisms at the center of our attention, or the genetic information that governs those features? Arvid Ågren helps us understand the attraction of the “selfish gene” view of evolution, as well as its shortcomings. This biological excursion has deep connections to philosophical issues of levels and emergence.Support Mindscape on Patreon.Arvid Ågren received his Ph.D. in Ecology and Evolutionary Biology from the University of Toronto. He is currently a Wenner-Gren Fellow at the Evolutionary Biology Centre at Uppsala University. Previously he worked at Cornell and Harvard. His recent book is The Gene’s-Eye View of Evolution.Web siteGoogle Scholar publicationsAmazon author pageTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

21 Feb 20221h 25min