Merel Kindt: How to Eliminate Phobias and PTSD Permanently

Merel Kindt: How to Eliminate Phobias and PTSD Permanently

Merel Kindt discusses how fear extinction can be achieved permanently, covering propranolol, epigenetics, psychedelics, and the broader implications of erasing fear. The conversation explores scientific approaches to phobias, PTSD, and future challenges in fear‑removal research.- 00:00 - Introduction to fear extinction- 14:07 - Propranolol and blood/brain barrier- 18:32 - Epigenetics and inherited fears- 26:33 - Removing fear of public speaking- 30:36 - PTSD- 33:45 - Psychedelics MDMA for self‑treatment- 37:29 - Pilot study with cigarette addiction- 42:31 - Should we get rid of fear? Consequences- 43:13 - MDMA vs LSD vs Psilocybin- 48:07 - Fear of silverfish- 50:13 - Modeling‑based phobias- 54:37 - Kindt 2009 paper on memory engrams- 55:34 - Kindt 2019 paper- 58:02 - Imagery scripting- 59:35 - Disgust removal?- 1:00:36 - How beta‑blockers work- 1:02:04 - Sleep for memory reconsolidation- 1:03:33 - Startle reflex measurement- 1:06:07 - Testing alternative beta‑blocker- 1:07:12 - Future challenges and limitationsSPONSORS:- Patreon: https://patreon.com/curtjaimungal- PayPal: https://bit.ly/2EOR0M4- Twitter: https://twitter.com/TOEwithCurt- Apple Podcasts: https://podcasts.apple.com/ca/podcast/better-left-unsaid-with-curt-jaimungal/id1521758802- Pandora: https://pdora.co/33b9lfP- Spotify: https://open.spotify.com/show/4gL14b92xAErofYQA7bU4e- Google Podcasts: https://play.google.com/music/listen?u=0#/ps/Id3k7k7mfzahfx2fjqmw3vufb44RESOURCES:- DOCUMENTARY SERIES: https://www.youtube.com/watch?v=pM3G6kITdYk- MEREL'S WEBSITE: https://kindtclinics.com/en/- http://betterleftunsaidfilm.com Theories of Everything with Curt Jaimungal features long-form, technically detailed interviews with leading researchers in physics, mathematics, consciousness, and philosophy, exploring topics at the level of active research. For academics, graduate students, and anyone seeking depth beyond popular science. SPONSOR: I subscribe to The Economist for their science and tech coverage. As a TOE listener, get 35% off! No other podcast has this: https://economist.com/TOE FOLLOW: Substack | Spotify | YouTube | Twitter Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

Episoder(340)

Bas van Fraassen: Why Science Does Not Reveal the Truth

Bas van Fraassen: Why Science Does Not Reveal the Truth

Professor Bas van Fraassen argues science doesn't deliver literal truth about reality, meaning unobservable physics is merely a model. He also contends the self isn't a thing and that logic permits fr...

15 Des 20252h 17min

Roger Penrose and Ivette Fuentes: A Bold New Test of Gravity

Roger Penrose and Ivette Fuentes: A Bold New Test of Gravity

Sir Roger Penrose and Professor Ivette Fuentes analyze the Ron Folman T-cubed experiment and whether the equivalence principle holds in quantum mechanics. They also detail gravity's role in wave funct...

25 Nov 20251h 13min

Curt Jaimungal: The Most Terrifying Philosopher I’ve Encountered

Curt Jaimungal: The Most Terrifying Philosopher I’ve Encountered

Curt Jaimungal dives into Kierkegaard’s three stages of life—aesthetic, ethical, and religious — showing how each promises freedom yet traps us in its own way. Through the lens of modern anxiety and c...

20 Nov 202518min

Ivette Fuentes: Quantum Gravity Predictions We Can Test Today

Ivette Fuentes: Quantum Gravity Predictions We Can Test Today

Professor Ivette Fuentes makes impossible physics testable, with verified predictions on the Casimir effect and quantum vacuum. Now she's building a "third way" to quantum gravity, a surprisingly simp...

10 Nov 20251h 9min

Curt Jaimungal: Can Physics Explain Its Own Laws?

Curt Jaimungal: Can Physics Explain Its Own Laws?

Why do physical laws have their specific form? Host Curt Jaimungal shows this question is a philosophical knot, because any "explanation" must itself stand on a law. Sponsors: - As a listener of TOE ...

5 Nov 202518min

Roger Penrose: Why The Big Bang Was Not The Beginning

Roger Penrose: Why The Big Bang Was Not The Beginning

Nobel laureate Sir Roger Penrose dismantles standard cosmology, arguing the Big Bang wasn't the beginning and quantum mechanics is fundamentally wrong. He then connects a real, gravitational wave func...

3 Nov 20251h 58min

Aaron Schurger: Neuroscience Does Not Threaten Free Will

Aaron Schurger: Neuroscience Does Not Threaten Free Will

The Libet experiment didn't kill free will, says professor of neuroscience Aaron Schurger; the brain's "readiness potential" is simply stochastic neural noise. We then tackle consciousness's role in i...

30 Okt 20251h 32min

Curt Jaimungal: Why I Don't Buy the Simulation Hypothesis (Nor Materialism)

Curt Jaimungal: Why I Don't Buy the Simulation Hypothesis (Nor Materialism)

Curt Jaimungal dismantles both the simulation hypothesis and materialism using consciousness arguments.One week ago, I (Curt Jaimungal) was invited to Niagara University to give the Peggy and John Day...

21 Okt 202557min

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