298 | Jeff Lichtman on the Wiring Diagram of the Brain

298 | Jeff Lichtman on the Wiring Diagram of the Brain

The number of neurons in the human brain is comparable to the number of stars in the Milky Way galaxy. Unlike the stars, however, in the case of neurons the real action is in how they are directly connected to each other: receiving signals over synapses via their dendrites, and when appropriately triggered, sending signals down the axon to other neurons (glossing over some complications). So a major step in understanding the brain is to map its wiring diagram, or connectome: the complete map of those connections. For a human brain that's an intimidatingly complex challenge, but important advances have been made on tinier brains. We talk with Jeff Lichtman, a leader in brain mapping, to gauge the current state of progress and what it implies.

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Blog post with transcript: https://www.preposterousuniverse.com/podcast/2024/12/09/298-jeff-lichtman-on-the-wiring-diagram-of-the-brain/

Jeff Lichtman received an MD/PhD from Washington University in St. Louis. He is currently the Jeremy R. Knowles Professor of Molecular and Cellular Biology and Santiago Ramón y Cajal Professor of Arts and Sciences at Harvard University. He is co-inventor of the Brainbow system for imaging neurons. He is a member of the National Academy of Sciences.

Episoder(415)

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53 | Solo -- On Morality and Rationality

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52 | Frank Lantz on the Logic and Emotion of Games

52 | Frank Lantz on the Logic and Emotion of Games

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24 Jun 20191h 4min

51 | Anthony Aguirre on Cosmology, Zen, Entropy, and Information

51 | Anthony Aguirre on Cosmology, Zen, Entropy, and Information

Cosmologists have a standard set of puzzles they think about: the nature of dark matter and dark energy, whether there was a period of inflation, the evolution of structure, and so on. But there are a...

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50 | Patricia Churchland on Conscience, Morality, and the Brain

50 | Patricia Churchland on Conscience, Morality, and the Brain

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49 | Nicholas Christakis on Humanity, Biology, and What Makes Us Good

49 | Nicholas Christakis on Humanity, Biology, and What Makes Us Good

It's easy to be cynical about humanity's present state and future prospects. But we have made it this far, and in some ways we're doing better than we used to be. Today's guest, Nicholas Christakis, i...

3 Jun 20191h 54min

48 | Marq de Villiers on Hell and Damnation

48 | Marq de Villiers on Hell and Damnation

If you're bad, we are taught, you go to Hell. Who in the world came up with that idea? Some will answer God, but for the purpose of today's podcast discussion we'll put that possibility aside and look...

27 Mai 20191h 11min

47 | Adam Rutherford on Humans, Animals, and Life in General

47 | Adam Rutherford on Humans, Animals, and Life in General

Most people in the modern world — and the vast majority of Mindscape listeners, I would imagine — agree that humans are part of the animal kingdom, and that all living animals evolved from a common an...

20 Mai 20191h 38min

46 | Kate Darling on Our Connections with Robots

46 | Kate Darling on Our Connections with Robots

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13 Mai 20191h 6min

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