#45 Statins: Prescribing Meds Day vs. Night Part 2 Mind the Gap Segment

#45 Statins: Prescribing Meds Day vs. Night Part 2 Mind the Gap Segment

Night and Day… join us for part II of our exploration into why we prescribe medications in the morning vs. at night, featuring statins! 03:28 How do statins and cholesterol synthesis work again, anyway? 04:00 Power in numbers - what do the meta-analyses say about timing of statins? 04:40 The long and short of it - how half-life may dictate when to take your statin. 07:35 Effect magnitude - does medication timing actually really impact patient outcomes? 10:30 Practical matters - so what should we tell patients? 11:05 Review of teaching points Show notes, transcripts and references (https://www.coreimpodcast.com/2019/07/24/statins-prescribing-meds-day-vs-night-part-2/) Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out Quince: https://quince.com/coreim * Use code FIGSRX for a great deal: https://wearfigs.com Advertising Inquiries: https://redcircle.com/brands Privacy & Opt-Out: https://redcircle.com/privacy

Episoder(213)

#141 Do Steroids Have a Role in Community-Acquired Pneumonia? Beyond Journal Club on the CAPE COD Trial

#141 Do Steroids Have a Role in Community-Acquired Pneumonia? Beyond Journal Club on the CAPE COD Trial

In community-acquired pneumonia, can steroids improve mortality? Past studies of steroids in CAP have been conflicting, with some showing a mortality benefit and others showing no difference. How does...

6 Des 202322min

#140 Bonus Pacemaker & ICDs: 5 Pearls Segment

#140 Bonus Pacemaker & ICDs: 5 Pearls Segment

Syncope history, PPM/ICD prior to MRI or surgery, anticoagulation for pacemaker or ICD procedures and new cardiac devices and how they may look different on EKG or chest x-ray!Sponsor: Post Investment...

29 Nov 202324min

#139 CKD Staging (Cr vs. Cystatin C, Albuminuria & more): Mind The Gap Segment

#139 CKD Staging (Cr vs. Cystatin C, Albuminuria & more): Mind The Gap Segment

Is Cr or Cystatin C better to assess eGFR? What are pros & cons of each? Does eGFR tell the full picture of kidney function? What may cause false positive albuminuria?Sponsor: Panacea Financial Studen...

8 Nov 202326min

#138 Incorporating Cancer Genetics into Your Practice: Lynch Syndrome and Beyond!

#138 Incorporating Cancer Genetics into Your Practice: Lynch Syndrome and Beyond!

Check out the original interview on Youtube:Essentials on Genetic Counselor | Lynch SyndromeWho should be referred for genetic counseling? How can we set our our patients and genetic counselors up for...

25 Okt 202332min

#137 Hypokalemia & Potassium Repletion: 5 Pearls Segment

#137 Hypokalemia & Potassium Repletion: 5 Pearls Segment

See some of the original interviews on Youtube!What is the evidence behind K+ repletion? What is a framework to think through for hypokalemia? What are the different repletion formulations and what el...

18 Okt 202334min

#136 How Did Diabetes Medications Become Obesity Meds? Beyond Journal Club on SURMOUNT-1 Trial

#136 How Did Diabetes Medications Become Obesity Meds? Beyond Journal Club on SURMOUNT-1 Trial

What is the difference between semaglutide (ozempic) and tirzepatide (mounjaro) in outcomes and mechanism? How did we find out diabetes medications can help with weight loss?Sponsors: Post Investment:...

4 Okt 202321min

#135 Guideline Directed Medical Therapy Part II: 5 Pearls Segment

#135 Guideline Directed Medical Therapy Part II: 5 Pearls Segment

With progressing CKD & HFrEF, what GDMT medications can you start, continue or stop? What does the data on hydralazine/isosorbide tell us and what does it NOT tell us? What are the pros and cons of st...

20 Sep 202336min

#134 Diagnostic Errors & Excellence

#134 Diagnostic Errors & Excellence

What does medical education research say about improving diagnostic errors? What habits help in getting to diagnostic excellence?Timestamps01:00 System 1 vs. System 207:46 Cognitive Biases13:46 Case f...

6 Sep 202330min

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