#166 Stress Ulcer Prophylaxis in the ICU and REVISE Trial: Beyond Journal Club with NEJM Group

#166 Stress Ulcer Prophylaxis in the ICU and REVISE Trial: Beyond Journal Club with NEJM Group

What’s the evidence been for the use of PPIs in mechanically ventilated patients? What do more recent studies reveal about PPIs and possible harmful side effects of aspiration pneumonia and C. difficile colitis? To find out, tune into the second season of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group.

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Timestamps:

(02:13) | Define the problem / Clinically important bleeding Outcome/Risk benefit /Risk factors]

(05:58) | Hx and H2 antagonists

(10:42) | SUP-ICU

(15:12) | PEPTIC

(19:30) | REVISE trial

(27:28) | Deprescribing

(29:06) | Outstanding questions

Transcript and Show Notes

Tags: CoreIM, InternalMedicine, CriticalCare, Proton Pump Inhibitors, GIbleeding, ICU, ICU bleeding, Clinical Trials, Evidence Based Medicine, Patient Centered Outcomes, Deprescribing



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Episoder(212)

#180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group

#180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group

How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care, examine how evidence evolved, and exp...

25 Jun 202526min

#179 Invasive Fungal Disease: 5 Pearls Segment

#179 Invasive Fungal Disease: 5 Pearls Segment

🔹 What is invasive fungal disease, and who is most at risk for developing invasive fungal disease? (~ 02:46)🔹 What are the main classes of fungi? (~11:35)🔹 What are the pros and cons of B-D Glucan ...

11 Jun 202545min

#178 Continuous Glucose Monitor (CGM): 5 Pearls Segment

#178 Continuous Glucose Monitor (CGM): 5 Pearls Segment

🔹What are clinically relevant limitations of an A1c vs. a CGM (1:40)🔹What do the different parts of the ambulatory glucose profile tell you? (09:59)🔹What are common pitfalls, medications, lifestyle...

2 Jun 202533min

#177 Interventional Radiology (IR) 101: 5 Pearls Segment

#177 Interventional Radiology (IR) 101: 5 Pearls Segment

🔹When is an U/S vs. CT vs. MRI helpful before consulting Interventional Radiology?🔹What factors go into an IR pre-op evaluation?🔹 When do drains go in, and when do they come out?🔹 When a patient h...

14 Mai 202543min

#176 Constipation Medications: 5 Pearls Segment

#176 Constipation Medications: 5 Pearls Segment

🔹 High-yield reversible causes of constipation? (02:26)🔹 Which type of fiber is more helpful? And is more hydration really better? And bulk-forming laxatives (9:03)🔹 Osmotic vs Stimulant Laxatives ...

30 Apr 202539min

#175 A Revolution in HIV Prevention & The PURPOSE Trials: Beyond Journal Club Segment with NEJM Group

#175 A Revolution in HIV Prevention & The PURPOSE Trials: Beyond Journal Club Segment with NEJM Group

How good are we at preventing HIV? How do efficacy and effectiveness differ? We journey from oral pre-exposure prophylaxis (PrEP) to long-acting injectables, and then to the PURPOSE trials, which look...

16 Apr 202527min

#174 Lp(a) and ASCVD Risk: 5 Pearls Segment

#174 Lp(a) and ASCVD Risk: 5 Pearls Segment

What does Lipoprotein(a) tell us that a standard lipid panel doesn’t? Should we be testing everyone for it? Dive into the genetics, clinical implications, and evolving management strategies for Lp(a)....

2 Apr 202543min

#173 Hypercoagulability Workup: 5 Pearls Segment

#173 Hypercoagulability Workup: 5 Pearls Segment

A new way to think of clots beyond provoked vs. unprovoked: Learn all about how important it is to think about reversibility! What patient states affect the inherited thrombophilia testing? Learn the ...

19 Mar 202544min

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