ERJ January 2018: The RESPIRE trials

ERJ January 2018: The RESPIRE trials

As part of the January issue, the European Respiratory Journal presents the latest in its series of podcasts. Deputy chief editor James Chalmers interviews the Anthony De Soyza (Newcastle University, Newcastle, UK) and Timothy Aksamit (Mayo Clinic, Rochester, MN, USA) about the RESPIRE1 and RESPIRE2 trials of ciprofloxacin in non-cystic fibrosis bronchiectasis. These two global phase III trials enrolled a total of 937 and test two dosing regimens tested (identical dose). The range of treatment estimates favours use of a ciprofloxacin dry powder inhaler (DPI), which was overall, well tolerated, with high compliance and an excellent safety profile. The ciprofloxacin DPI 14-day regimen gave a 144-day delay in the to time to first exacerbation and a 25% reduction in the frequency of exacerbations, and the 28-day regimen gave a 138-day delay in to time to first exacerbation and a 28% reduction in frequency of exacerbations.

Episoder(78)

ERJ Podcast July 2025: Implementation of European national driving regulations for OSA

ERJ Podcast July 2025: Implementation of European national driving regulations for OSA

As part of the July issue, the European Respiratory Journal presents the latest in its series of podcasts. Deputy Chief Editor Don Sin interviews Walter McNicholas (School of Medicine and the Conway R...

31 Jul 202512min

ERJ Podcast January 2025: Treatment response to mepolizumab in severe eosinophilic asthma

ERJ Podcast January 2025: Treatment response to mepolizumab in severe eosinophilic asthma

As part of the January issue, the European Respiratory Journal presents the latest in its series of podcasts. Deputy Chief Editor Don Sin interviews Dr Peter Gibson about distinct trajectories of trea...

30 Jul 202513min

ERJ Podcast June 2025: Mechanistic studies in interstitial lung disease

ERJ Podcast June 2025: Mechanistic studies in interstitial lung disease

As part of the June issue, the European Respiratory Journal presents the latest in its series of podcasts. Deputy Chief Editor Don Sin interviews Associate Editor Bruno Crestani about a series of arti...

2 Jul 202515min

ERJ Podcast May 2025: Efficacy and safety of the activin signalling inhibitor sotatercept

ERJ Podcast May 2025: Efficacy and safety of the activin signalling inhibitor sotatercept

As part of the May issue, the European Respiratory Journal presents the latest in its series of podcasts. Chief Editor James Chalmers interviews Associate Editor Marius Hoeper about the efficacy and s...

29 Mai 202515min

ERJ Podcast April 2025: Continuous positive airway pressure and mandibular advancement splints

ERJ Podcast April 2025: Continuous positive airway pressure and mandibular advancement splints

As part of the April issue, the European Respiratory Journal presents the latest in its series of podcasts. Deputy Chief Editor Don Sin interviews Dr Fernanda Almeida about the CHOICE multicentre, ope...

1 Mai 202511min

ERJ Podcast March 2025: Generalisability of pharmaceutical randomised controlled trial eligibility criteria for progressive pulmonary fibrosis

ERJ Podcast March 2025: Generalisability of pharmaceutical randomised controlled trial eligibility criteria for progressive pulmonary fibrosis

As part of the March issue, the European Respiratory Journal presents the latest in its series of podcasts. Deputy Chief Editor Don Sin interviews Associate Editor Yet Khor about the generalisability ...

1 Apr 202512min

ERJ Podcast February 2025: Pre- and post-bronchodilator spirometry in COPD

ERJ Podcast February 2025: Pre- and post-bronchodilator spirometry in COPD

As part of the February issue, the European Respiratory Journal presents the latest in its series of podcasts. Chief Editor James Chalmers interviews Associate Editor Dave Singh about pre- and post-br...

26 Feb 202512min

ERS Monograph: Lung Transplantation

ERS Monograph: Lung Transplantation

Leaders in the transplantation field and well-regarded ERS Officers, Michael Perch and Federica Meloni, join Dorina Esendagli in a podcast focusing on the latest Monograph: Lung Transplantation. Cover...

10 Feb 202518min

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