Genetic testing in epilepsy: Who, how, and why? Dr. Ilona Krey

Genetic testing in epilepsy: Who, how, and why? Dr. Ilona Krey

Send comments and feedback This first episode in a multipart series on genetics in epilepsy covers the basics of genetic testing. Dr. Alina Ivaniuk interviews Dr. Ilona Krey, a physician and researcher at the Institute of Human Genetics at Leipzig University Medical Center. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. Let us know how we're doing: info@ilae.org The International League Against Epilepsy is the world's preeminent...

Episoder(102)

Drug-resistant epilepsy: Dr. Patrick Kwan

Drug-resistant epilepsy: Dr. Patrick Kwan

Send comments and feedback About one-third of people with epilepsy will continue having seizures despite medications. What is the clinical definition of drug-resistant epilepsy? Why does it occur, and...

24 Nov 202532min

Normalizing depression in epilepsy: Screening, diagnosis, treatment - Dr. Rosa Michaelis

Normalizing depression in epilepsy: Screening, diagnosis, treatment - Dr. Rosa Michaelis

Send comments and feedback Nearly 1 in 4 people with epilepsy experiences depression, which affects quality of life, seizure control, and adherence to treatment. Depressive symptoms - including suicid...

10 Nov 202522min

A novel patient-reported outcome measure for epilepsy: The impacts of seizures and treatment

A novel patient-reported outcome measure for epilepsy: The impacts of seizures and treatment

Send comments and feedback Is there a fast, simple way to measure whether someone with epilepsy is doing "better" or "worse" compared with a past clinic visit? Not really. Seizure count is often consi...

27 Okt 202518min

Social work in epilepsy: Closing the treatment gap and improving quality of life - Dr. Rugare Mugumbate

Social work in epilepsy: Closing the treatment gap and improving quality of life - Dr. Rugare Mugumbate

Send comments and feedback Closing the epilepsy treatment gap relies heavily on social and cultural acceptance of epilepsy as a brain disorder that can be managed with medication or other therapies. D...

13 Okt 202530min

Somatic genetic epilepsies: Dr. Christian Bosselmann

Somatic genetic epilepsies: Dr. Christian Bosselmann

Send comments and feedback Somatic genetic epilepsies arise from mutations that occur early in fetal development. They are usually only detectable by genetic sequencing of tissue. For these epilepsies...

29 Sep 202531min

Research recap: Empiric immunotherapy for highly refractory epilepsy: Dr. Elisabeth Doran

Research recap: Empiric immunotherapy for highly refractory epilepsy: Dr. Elisabeth Doran

Send comments and feedback In a retrospective study of 31 patients with highly refractory epilepsy, 29% had more than a 50% reduction in seizures for at least 12 months after being treated with immuno...

8 Sep 202512min

Genetic testing: Variants of uncertain significance (VUS) - Dr. Gemma Carvill

Genetic testing: Variants of uncertain significance (VUS) - Dr. Gemma Carvill

Send comments and feedback What are variants of uncertain significance (VUS) in epilepsy genetic testing? How are they defined, and can those definitions change over time? Sharp Waves talks with Dr. G...

18 Aug 202534min

What's new in status epilepticus: Dr. Eugen Trinka

What's new in status epilepticus: Dr. Eugen Trinka

Send comments and feedback This episode covers a wide scope of issues, including treatment options, treatment response, prognosis and the role of seizures versus the underlying etiology, most common e...

4 Aug 202546min

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