175 | William Ratcliff on Multicellularity, Physics, and Evolution

175 | William Ratcliff on Multicellularity, Physics, and Evolution

We've talked about the very origin of life, but certain transitions along its subsequent history were incredibly important. Perhaps none more so than the transition from unicellular to multicellular organisms, which made possible an incredible diversity of organisms and structures. Will Ratcliff studies the physics that constrains multicellular structures, examines the minute changes in certain yeast cells that allows them to become multicellular, and does long-term evolution experiments in which multicellularity spontaneously evolves and grows. We can't yet create life from non-life, but we can reproduce critical evolutionary steps in the lab.

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William Ratcliff received his Ph.D. in Ecology, Evolution, and Behavior at the University of Minnesota. He is currently Associate Professor in the School of Biological Sciences at Georgia Tech. Among his awards are a Packard Fellowship and being named in Popular Science's "Brilliant 10" of 2016.


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Episoder(437)

362 | Luis Bettencourt on the Universal Properties of Self-Organizing Cities

362 | Luis Bettencourt on the Universal Properties of Self-Organizing Cities

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27 Jul 1h 20min

361 | Bonnie Bassler on How Bacteria Talk and Work Together

361 | Bonnie Bassler on How Bacteria Talk and Work Together

One of the characteristics of life is that living organisms gather information and put it to use. Even one of the simplest lifeforms, bacteria, are able to sense features of their surroundings and alt...

20 Jul 1h 15min

Mindscape Ask Me Anything, Sean Carroll | July 2026

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Welcome to the July 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreo...

13 Jul 4h 3min

360 | Marc Berman on the Science of Touching Grass

360 | Marc Berman on the Science of Touching Grass

Modern life has, in many ways, removed us from the environments in which our ancestors lived and adapted. Not only do we spend time looking at screens, but we spend time indoors, or outdoors but in ur...

6 Jul 1h 29min

359 | Solo: Theories of Dark Energy

359 | Solo: Theories of Dark Energy

The cosmological constant, as discussed last episode, provides a perfectly good (thus far) explanation for why we observe the universe to be accelerating. But it might not be the right explanation, an...

29 Jun 1h 56min

358 | Solo: Vacuum Energy and the Cosmological Constant

358 | Solo: Vacuum Energy and the Cosmological Constant

The most surprising discovery in fundamental physics during my career as a scientist was undoubtedly the acceleration of the universe, announced in 1998. The most straightforward explanation for these...

22 Jun 1h 59min

357 | Jeff Coller on mRNA, Vaccines, and Bespoke Therapeutics

357 | Jeff Coller on mRNA, Vaccines, and Bespoke Therapeutics

Messenger RNA (mRNA) plays a literally central role in the functioning of life as we know it, shuttling information back and forth between the DNA where it is stored to the ribosome where it is used t...

15 Jun 1h 19min

356 | Andrea Wulf on Enlightenment, Nature, Romanticism, and Modernity

356 | Andrea Wulf on Enlightenment, Nature, Romanticism, and Modernity

All ideas have a history, no matter how inevitable and well-entrenched they may seem to us today. The later Enlightenment was a heady time when people were exploring new conceptions of nature, humanit...

8 Jun 1h 17min

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