Science Magazine Podcast6 Jun 2024

Putting mysterious cellular structures to use, and when brown fat started to warm us up

Despite not having a known function, cellular “vaults” are on the verge of being harnessed for all kinds of applications, and looking at the evolution of brown fat into a heat-generating organ First on this week’s show, Managing News Editor John Travis joins host Sarah Crespi to discuss mysterious cellular complexes called “vaults.” First discovered in the 1980s, scientists have yet to uncover the function of these large, common, hollow structures. But now some researchers are looking to use vaults to deliver cancer drugs and viruses for gene therapy. Next, what can we learn about the evolution of brown fat from opossums? Unlike white fat, which stores energy in many mammals, brown fat cells use ATP to generate heat, helping babies maintain their body temperature and hibernators kick-start their summers. Susanne Keipert, a researcher in the Department of Molecular Biosciences at Stockholm University’s Wenner-Gren Institute, talks about when in evolutionary history brown fat took on this job of burning energy. Finally, this week we are launching our music refresh! If you are interested in what happened to our music—where it came from and how it’s different (and the same)—stay tuned for a chat with artist Nguyên Khôi Nguyễn. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; John Travis Episode page: https://www.science.org/doi/10.1126/science.zpoy92t Learn more about your ad choices. Visit megaphone.fm/adchoices

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Episoder(641)

A team effort to save a giant fish, the power of moonlight, and how scientists can navigate a tough political environment

First up on the podcast, along Brazil’s Juruá River, local residents have been working with scientists to manage a giant fish called the arapaima—affecting the land, the people, and the economy. Contr...

7 Mai 53min

Watching a spiders’ heart beat, epigenetic ethics, and what science biographies reveal about fame

First up on the podcast, Online News Editor David Grimm shares a batch of fun stories with podcast host Sarah Crespi—from spider hearts racing when traffic gets loud to a disease-preventing house. Sta...

30 Apr 46min

Cleaning up uranium mining, and how the heart avoids cancer

First up on the podcast, freelance science and environmental journalist Quentin Septer joins host Sarah Crespi to talk about a controversial uranium mine getting fast-tracked in South Dakota. Septer c...

23 Apr 30min

The normals | Episode 3

The final of a three-part limited Science Podcast series that looks at the history of normal human subjects in research In episode two, we heard what happened to the normals program after church volu...

21 Apr 33min

How to keep quantum computers cool, whether prediction markets harm public health, and podcasting on podcasting

First up on the podcast, quantum computers require extremely low temperatures—less than 1°C away from absolute zero. But getting down to those temperatures has usually required dilution fridges using ...

16 Apr 50min

The Normals | Episode 2

Last time on The Normals, we learned that in the 1950s, the National Institutes of Health (NIH) wanted to recruit many healthy volunteers for basic research. Two peace churches, the Mennonites and the...

14 Apr 27min

A chimpanzee ‘civil war,’ and NASA plans for nuclear propulsion

First up on the podcast, freelance science journalist Hannah Richter joins host Sarah Crespi to discuss NASA’s plans to send a nuclear-powered spacecraft to Mars in less than 3 years. Having not launc...

9 Apr 42min

The Normals | Episode 1

How do we know what's normal in a person? In the early 1950s, the National Institutes of Health (NIH) set out to do something unprecedented. It wanted to start studying normal humans on a grand scale....

7 Apr 23min