Genetic testing for epilepsy surgery: Dr. Pat Moloney

Genetic testing for epilepsy surgery: Dr. Pat Moloney

Send comments and feedback In the second episode of our genetics and epilepsy series, Sharp Waves explores how genetic insights can inform considerations and outcomes of epilepsy surgery. Dr. Alina Ivaniuk interviews Dr. Patrick Moloney, currently an epilepsy genomics fellow at the Chalfont Center for Epilepsy at University College London. Selected publications: Do germline genetic variants influence surgical outcomes in drug-resistant epilepsy? Epilepsy Res 2024 Genomics in the presurgical...

Episoder(102)

Valproate and reproductive risks in women and men with epilepsy: Dr. Tony Marson

Valproate and reproductive risks in women and men with epilepsy: Dr. Tony Marson

Send comments and feedback In use since the 1970s, valproate is highly effective for genetic generalized epilepsies and some forms of pediatric epilepsy. The medication also is associated with a 10% r...

21 Jul 202522min

ILAE Updated seizure classification: Dr. Sandor Beniczky

ILAE Updated seizure classification: Dr. Sandor Beniczky

Send comments and feedback ILAE's updated seizure classification position paper was published in Epilepsia in April 2025. Sharp Waves talked with Dr. Sandor Beniczky about the updates and how they wil...

7 Jul 202513min

Documentary filmmaker confronts epilepsy in a new memoir: Stacia Kalinoski

Documentary filmmaker confronts epilepsy in a new memoir: Stacia Kalinoski

Send comments and feedback Seizures cost Stacia Kalinoski her career in broadcast journalism and forced her to give up running. In her new memoir, Kalinoski recounts her journey from first seizure in ...

23 Jun 202515min

Work-life balance: Dr. Sheryl Haut

Work-life balance: Dr. Sheryl Haut

Send comments and feedback Work-related stress and burnout are common in physicians, with rates of burnout estimated between 25% and 60%. These stresses impact physician health, patient care, and heal...

9 Jun 202522min

The role of microglia in epilepsy: Hero, villain, or both? Dr. Amy Brewster

The role of microglia in epilepsy: Hero, villain, or both? Dr. Amy Brewster

Send comments and feedback Microglia can have protective and also potentially harmful effects in the brain. They seem to be involved in dampening the nervous system during acute seizures – but also ap...

27 Mai 202519min

Language models reveal concerns of people with epilepsy in online discussions

Language models reveal concerns of people with epilepsy in online discussions

Send comments and feedback Many of the most common concerns of people with epilepsy are topics they don't usually talk about with physicians. This is one of many findings of a study using AI to analyz...

12 Mai 202531min

Music, epilepsy, and the brain: Dr. Phillip Pearl & Prof. Nigel Osborne

Music, epilepsy, and the brain: Dr. Phillip Pearl & Prof. Nigel Osborne

Send comments and feedback Music can affect emotions, spark memories, and influence mood. In cases of musicogenic epilepsy, music can trigger seizures. In other cases, music may reduce seizure frequen...

28 Apr 202526min

Genetic testing for epilepsy in low-resource regions

Genetic testing for epilepsy in low-resource regions

Send comments and feedback In lower- and middle-income countries, raising awareness of genetic etiologies in epilepsy and genetic testing options may ultimately shift national priorities toward making...

14 Apr 202524min

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