The New Fasting Protocol to Increase Lifespan by 96% | Chris Rhodes : 1254

The New Fasting Protocol to Increase Lifespan by 96% | Chris Rhodes : 1254

Can You Mimic Fasting—Without Actually Fasting?

Chris Rhodes, a biochemist and longevity researcher, joins Dave to reveal a groundbreaking fasting mimetic that could revolutionize how we approach aging, metabolism, and health.

Fasting is one of the most powerful tools for longevity, but what if you could achieve the same benefits without hunger, energy crashes, or social sacrifices? Scientists have identified key compounds that mimic fasting at the cellular level—offering a way to extend lifespan, boost metabolism, and enhance cognitive function without giving up food.

Enter Mimio, a blend of four key molecules naturally produced during fasting, is engineered to deliver the life-extending benefits of fasting—without starvation.

For decades, fasting has been the gold standard for longevity, but over-fasting can wreck hormones, metabolism, and muscle mass. So, what if you could get the benefits of a 36-hour fast without the downsides? Chris breaks down the science behind fasting, autophagy, and the game-changing compounds that trick your body into entering a fasted state—even while eating.


What You’ll Learn:

• The optimal fasting window for maximizing lifespan (Hint: It’s not 16 hours)

• The four fasting metabolites that extend life by 96%

• How Mimio mimics fasting benefits—without giving up food

• The real reason over-fasting destroys your metabolism and hormones

• Why traditional longevity drugs (Metformin, Rapamycin) fall short

• Can you build muscle and burn fat at the same time? The science of mTOR & AMPK

• Why Big Pharma doesn’t want you to know about this breakthrough


*** Get 20% off Mimio at mimiohealth.sjv.io/3J9abX with code: DAVE ***


Sponsors:

Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.

Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.


Resources:

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

Mimio Instagram: https://www.instagram.com/mimiohealth/

Mimio Website: https://mimiohealth.com/

2025 Biohacking Conference: https://biohackingconference.com/2025

Danger Coffee: https://dangercoffee.com

Dave Asprey’s Website: https://daveasprey.com

Dave Asprey’s Linktree: https://linktr.ee/daveasprey

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com

Own an Upgrade Labs: https://ownanupgradelabs.com

Upgrade Labs: https://upgradelabs.com

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com


Timestamps:

00:00 – Intro

00:58 – Fasting & Longevity

01:88 – Optimal Fasting Length

03:39 – Alternate Day Fasting: Pros & Cons

05:50 – Key Fasting Compounds

07:34 – Spermidine & Longevity Molecules

11:41 – FDA Roadblocks on Natural Compounds

15:37 – AI, Big Data & Longevity Research

31:19 – Mimio’s Impact on Testosterone & Aging

35:16 – Longevity & Death Philosophy

36:48 – Biohacking Origins

37:03 – Metabolism & Cognitive Function

38:35 – Unexpected Effects of Fasting

40:43 – Fasting & Circadian Rhythms

43:09 – Mimio Science & Benefits

45:14 – Mimio in a Daily Routine

55:05 – Men vs. Women: Fasting Differences

01:02:23 – Future of Nutrition & Biohacking

01:07:21 – Conclusion & Discount Code

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episoder(1461)

Bulletproof Radio Q&A #130

Bulletproof Radio Q&A #130

On this episode of Bulletproof Radio, we have carefully selected the best questions from Facebook, Twitter, and the Bulletproof® Forums for another awesome Q&A!  Thanks to you, the listener! Hear a thought-provoking conversation and gain a ton of useful knowledge in this episode about the art of biohacking, nutrition, and… well… kicking ass at life in general! Dave and Zak talk about supplements and how they affect the gut, what they feed their kids, how to be Bulletproof® on a budget, and why grass fed butter is way better for you than raw crème in your Bulletproof® Coffee (not to mention ten times cheaper too!). It’s been a while since the last Q&A and we’re sorry, but please enjoy the show!  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Jun 20141h 11min

Sleeping for Performance with Neurotechnology - Podcast #129

Sleeping for Performance with Neurotechnology - Podcast #129

Sleep experts Dr. Phillip Westbrook, M.D. and Clinical Professor of Medicine at UCLA, and Dan Levendowski, Co-founder of Advanced Brain Monitoring (ABM) come on Bulletproof Radio to uncover the foundation for how to hack your sleep using the latest cutting-edge technology. Levendowski shares his personal story of using this technology to confirm that he was waking up 70 times per hour because of sleep apnea. Also hear about optimal sleep positions, how obesity causes sleep problems, and why getting kicked by your spouse when you snore is a good thing.     Aside from being the co-founder of ABM, Dan Levendowski is a serial inventor who has spearheaded the development of numerous disruptive medical technologies. He has also served as principal investigator for 17 National Institute of Health research grants managing over $8 million in funding for research in chronic disease, physiology, and performance optimization. He has co-authored more than 20 journal articles and 15 papers for new product adoption and has an award winning winery. Dr. Phillip Westbrook has had an extensive career as a medical physician specializing in pulmonary disease and physiology. Dr. Westbrook has presented over 100 guest lectures to professional organizations, was Editor-in-Chief of the Sleep Medicine Review, an editor for Sleep, a guest reviewer for Chest and an Ad Hoc reviewer for The New England Journal of Medicine.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

14 Jun 201451min

#128 Andy Hnilo and Skin Care – Special Episode

#128 Andy Hnilo and Skin Care – Special Episode

Today’s episode of Bulletproof Radio is short and sweet, but packed full of Andy Hnilo. Andy is a model and actor who had a life-changing car accident leading him to create a skin care line that he personally used to heal his injuries and detox his skin. You will also hear him share the science behind clay and how you can combine these age-old techniques with new ones to improve sleep and sex. Stay tuned for a full episode with Andy where he talks more in-depth with Dave about Alitura Naturals and the benefits of clay.     Andy had a life-changing event when he was run over by two SUV’s that left him with his jaw wired shut and injuries all over his body. This event transformed him and drives his passion to share his new skin care line Alitura Naturals. Enjoy the show.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

11 Jun 201416min

#127 Tim Ferriss on Smart Drugs, Performance, and Biohacking

#127 Tim Ferriss on Smart Drugs, Performance, and Biohacking

Okay so it’s not really a 4-hour show (this time), but it is heavy nonetheless. The 4-Hour man himself, Tim Ferriss, is on Bulletproof Radio to unleash his biohacking expertise and to share some knowledge. Tim has a new podcast called The Tim Ferriss Show and on this episode of Bulletproof Radio you hear him on the other side of the mic talking about his view on smart drugs, tea as a creative stimulant, eating insects, and how sex is better than porn for your biochemistry.     The 4-Hour Workweek, The 4-Hour Body, and The 4-Hour Chef have been #1 New York Times bestsellers and Tim Ferriss has been listed as one of the most Most Innovative Business People and a Forbes Magazine “Names You Need to Know”. He is a biohacker and self-experimenting guinea pig. His blog The Four-Hour Blog chronicles his never-ending quest for self-improvement and shares a wealth of information. Enjoy the show. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

3 Jun 201442min

#126 Dr. Ritchie Shoemaker on Surviving Mold

#126 Dr. Ritchie Shoemaker on Surviving Mold

On this episode of Bulletproof Radio, Dr. Ritchie Shoemaker, a practicing physician recovered from his own mold-related illness, talks the science behind the silent epidemic of mold. You will hear how genomics and testing is opening the door to understanding mold illness, and why microbes growing in water-damaged buildings make people sick. Have you ever wondered why some people can’t walk into a moldy building and others don’t seem to notice? Dr. Shoemaker has the answers and gives you the facts. Intimidated by the topic? Look for the Quick Reference Guide to this podcast on the Bulletproof Executive blog for terms and definitions, so you can easily be an expert too.     Dr. Ritchie Shoemaker is a practicing physician in Maryland and the author of eight books and multiple published academic papers. His latest book Surviving Mold: Life in the Era of Dangerous Buildings is a guide through diagnosis and treatment, remediation and a return to health. He is an expert on mold, having “looked death in the face” from his own mold-related illness. He lectures throughout the US on chronic inflammatory illnesses that are caused by exposure to moldy buildings and mycotoxins. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

30 Mai 20141h 1min

#125 Cows Can Save the Planet with Judith Schwartz

#125 Cows Can Save the Planet with Judith Schwartz

In this episode of Bulletproof Radio, you hear from therapist-turned-environmental economist Judith D. Schwartz. Her new book, Cows Save the Planet, is a manifesto about nature’s very own gut - the soil. In this fascinating conversation learn how to reverse desertification, why cow poop is necessary for a healthy ecosystem, and why it’s fundamental to the web of life.     Judith D. Schwartz is a longtime freelance writer and published author. She is an expert in Environmental Economics with an education from Brown University, Columbia University Graduate School of Journalism, and a Master’s in Counseling Psychology from Northwestern. She trained as a psychoanalyst and wrote a novel based on her grandmother’s psychoanalyst who was a member of Freud’s inner circle in Vienna. Judith currently lives and works in southern Vermont and is devoted to sharing her knowledge about cows, soil, and the restoration of the earth’s ecosystem.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Mai 201438min

#124 Resistant Starch Revealed with Richard Nikoley and Tim Steele

#124 Resistant Starch Revealed with Richard Nikoley and Tim Steele

Resistant starch... sounds interesting! And you’ve probably heard mention of it lately, but do you really know what it is? On this episode of Bulletproof Radio, hear Resistant Starch experts, Richard Nikoley and Tim Steele, talk about what it is and how to use it. The show is packed with key insights about how to figure out your own gut biome from potato starch to fecal transplants. Sound gross? It is, and fascinating! Plus you’ll hear the top 3 probiotics we can all start taking right now to improve our gut flora.     Richard Nikoley is a former Navy officer, successful entrepreneur, and creator of the highly informative blog Free The Animal. He is joined by Tim Steele, aka “Tater Tot” (a nickname hinting at his experimentation with potatoes). Tim has helped the re-emergence of resistance starch as a guest writer on Free The Animal and Dr. Grace Liu’s blog, Animal Pharm. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

23 Mai 20141h 1min

#122 Donna Gates on Body Ecology

#122 Donna Gates on Body Ecology

International best-selling author Donna Gates comes on Bulletproof Radio to discuss why gut ecology is vitally important to your performance, and how healing it can be beneficial even for those of us that don’t have digestive problems – but chances are you probably have at least some underlying issues. On the show you’ll learn three things to start doing now for better gut health along with a simple breakdown on which digestive enzymes you should be taking.     Donna Gates is the founder of The Body Ecology Diet, a sugar-free, gluten-free, casein-free, and probiotic-rich way of eating. She is the best-selling author of The Body Ecology Diet: Recovering Your Health and Rebuilding Your Immunity as well as her other books The Body Ecology Guide to Growing Younger: Anti-Aging Wisdom for Every Generation, and Stevia: Cooking with Nature’s Calorie-Free Sweetener. Donna coined the term “Inner Eco-System” over 20 years ago and has since been helping people use probiotics and fermentation to find their individual inner ecology. Enjoy!  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Mai 201439min

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