The New Fasting Protocol to Increase Lifespan by 96% | Chris Rhodes : 1254

The New Fasting Protocol to Increase Lifespan by 96% | Chris Rhodes : 1254

Can You Mimic Fasting—Without Actually Fasting?

Chris Rhodes, a biochemist and longevity researcher, joins Dave to reveal a groundbreaking fasting mimetic that could revolutionize how we approach aging, metabolism, and health.

Fasting is one of the most powerful tools for longevity, but what if you could achieve the same benefits without hunger, energy crashes, or social sacrifices? Scientists have identified key compounds that mimic fasting at the cellular level—offering a way to extend lifespan, boost metabolism, and enhance cognitive function without giving up food.

Enter Mimio, a blend of four key molecules naturally produced during fasting, is engineered to deliver the life-extending benefits of fasting—without starvation.

For decades, fasting has been the gold standard for longevity, but over-fasting can wreck hormones, metabolism, and muscle mass. So, what if you could get the benefits of a 36-hour fast without the downsides? Chris breaks down the science behind fasting, autophagy, and the game-changing compounds that trick your body into entering a fasted state—even while eating.


What You’ll Learn:

• The optimal fasting window for maximizing lifespan (Hint: It’s not 16 hours)

• The four fasting metabolites that extend life by 96%

• How Mimio mimics fasting benefits—without giving up food

• The real reason over-fasting destroys your metabolism and hormones

• Why traditional longevity drugs (Metformin, Rapamycin) fall short

• Can you build muscle and burn fat at the same time? The science of mTOR & AMPK

• Why Big Pharma doesn’t want you to know about this breakthrough


*** Get 20% off Mimio at mimiohealth.sjv.io/3J9abX with code: DAVE ***


Sponsors:

Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.

Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.


Resources:

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

Mimio Instagram: https://www.instagram.com/mimiohealth/

Mimio Website: https://mimiohealth.com/

2025 Biohacking Conference: https://biohackingconference.com/2025

Danger Coffee: https://dangercoffee.com

Dave Asprey’s Website: https://daveasprey.com

Dave Asprey’s Linktree: https://linktr.ee/daveasprey

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com

Own an Upgrade Labs: https://ownanupgradelabs.com

Upgrade Labs: https://upgradelabs.com

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com


Timestamps:

00:00 – Intro

00:58 – Fasting & Longevity

01:88 – Optimal Fasting Length

03:39 – Alternate Day Fasting: Pros & Cons

05:50 – Key Fasting Compounds

07:34 – Spermidine & Longevity Molecules

11:41 – FDA Roadblocks on Natural Compounds

15:37 – AI, Big Data & Longevity Research

31:19 – Mimio’s Impact on Testosterone & Aging

35:16 – Longevity & Death Philosophy

36:48 – Biohacking Origins

37:03 – Metabolism & Cognitive Function

38:35 – Unexpected Effects of Fasting

40:43 – Fasting & Circadian Rhythms

43:09 – Mimio Science & Benefits

45:14 – Mimio in a Daily Routine

55:05 – Men vs. Women: Fasting Differences

01:02:23 – Future of Nutrition & Biohacking

01:07:21 – Conclusion & Discount Code

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episoder(1460)

#60 Orgasmic Meditation & Hacking Your Sex Life, with Dr. Pooja Lakshmin

#60 Orgasmic Meditation & Hacking Your Sex Life, with Dr. Pooja Lakshmin

Discover orgasmic meditation (OMing) and the science behind it with Dr. Pooja Lakshmin, M.D., the CSO of OneTaste, and scientist at Rutgers University Newark Orgasm Laboratory. This episode discusses the relationship between orgasm and the nervous system, the importance of mindfulness, and how often men and women should orgasm for maximum performance in life. Be sure not to miss this stimulating episode! Formerly a psychiatrist at Stanford hospital, Pooja switched career paths after experimenting with OMing and researching the science behind it. She later moved across the country to New York City to study the neuroscience involved in OMing through fMRI imaging and clinical studies. Currently, Pooja continues to conduct OMing studies, while also venturing into further researching the male orgasm. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

12 Sep 201346min

#59 Hacking Productivity, Forming Habits & 'Lift' iPhone App, With Tony Stubblebine

#59 Hacking Productivity, Forming Habits & 'Lift' iPhone App, With Tony Stubblebine

Learn how to unlock your Bulletproof potential from the CEO of the habit-building app, Lift. Tony Stubblebine shares his take on what habits are good to form, and how to develop and sustain those habits by creating a supportive lifestyle. Tony and I also dug deep into the performance and emotional aspects of being a CEO. If you are a productivity hack or a high performing businessperson, than you do not want to miss this episode! Tony Stubblebine co-founded Lift based on the idea that positive reinforcement and community support could be deployed universally to help people achieve their goals. Prior to Lift, he was the founder and CEO of CrowdVine Event Social Networks, which builds simple and powerful software to help people connect and meet. He was also a part of the Wesabe launch team, Director of Engineering at Odeo.com and O'Reilly Media, and authored Regular Expression Pocket Reference. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Sep 201354min

#58 Food Choices, Willpower & Sugar Cravings with Michael Fishman

#58 Food Choices, Willpower & Sugar Cravings with Michael Fishman

Take control of your food choices, understand your willpower, and combat sugar cravings by listening to this episode with expert health marketing advisor, Michael Fishman. You will hear how Michael radically changed his diet to be a healthier, more in control and happier version of himself, and how you can do that too. Michael Fishman is a leading advisor on marketing, positioning and strategy for health, wellness and personal development businesses and personalities such as Rodale's Prevention and Men's Health publishing brands, Dr. Andrew Weil, Dr. Mark Hyman, Dr. Christiane Northrup, Dr. Dean Ornish and many others. Michael is also a highly sought after speaker on how marketing language, customer care and work culture combine to take companies from merely good to the beloved best at what they do. He created the annual Consumer Health Summit, which is the preeminent invitational forum for CEOs, entrepreneurs and marketing leaders in health and wellness. He is also a co-founder of BehaviorCon, a conference on marketing and consumer psychology.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Aug 201347min

#57 Becoming Alpha, Dispelling Myths & Making Changes, with Adam Bornstein

#57 Becoming Alpha, Dispelling Myths & Making Changes, with Adam Bornstein

As a top health and fitness editor and best-selling author, Adam Bornstein came on the show to share what it means to be ‘Alpha’ and how being bulletproof is possible for everyone. In this episode, Adam and I discuss our shared egg obsession, whether cheat days are helpful or harmful, and how mental barriers keep you from achieving the best version of yourself. You will even get a glimpse into the workings of mainstream media, research, and health journalism. Adam Bornstein is a biohacking, solutions oriented machine! Adam has been named “one of the most influential people in health.” He’s a long time health and fitness writer and editor for magazines like Men’s Health and Livestrong, and best-selling author of four fitness books, including his most recent book “Man 2.0 Engineering the Alpha: A Real World Guide to an Unreal Life: Build More Muscle. Burn More Fat. Have More Sex” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Aug 201354min

#56 Biohacking Apocalypse Survival, Stress Inoculation & Shamans, with Sam Sheridan

#56 Biohacking Apocalypse Survival, Stress Inoculation & Shamans, with Sam Sheridan

In an apocalypse, how would you biohack your survival? This episode dives into answering this question and discusses all things stress-related. It was a blast having Sam Sheridan, best selling author of The Disaster Diaries: How I Learned to Stop Worrying and Love the Apocalypse, on the show to talk about a wide variety of topics ranging from endurance vs. interval training to Cooper’s Color Code and shamans. You’ll hear about the science and psychology of stress, the best way to handle stress, and how to better your chances of surviving an apocalypse. Sam Sheridan was an amateur MMA fighter, EMT, wild-land fire fighter, cowboy, sailor and worked construction at the South Pole. He is also the best selling author of A Fighters Heart: One Man’s Journey Through the World of Fighting, he Fighters Mind: Inside the Mental Game. During research for his latest book The Disaster Diaries: Sam immerses himself in the survivalist and dooms-day preparation subculture by:  Attending stunt driving school;  Learning the art of eskrima (Filipino knife fighting); Participating in Cody Lundin’s (Dual Survival on Discovery Channel) Aboriginal Living Skills School; Learning how to steal a car with ex-gang bangers in Los Angeles. A large portion of The Disaster Diaries explains the bio-chemical cocktail that our bodies produce during moments of intense stress (i.e.  an apocalypse.)  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Aug 201350min

#55 Fitness, Nutrition & Bulletproof Habits, with High Performance Health Coach, Yuri Elkaim

#55 Fitness, Nutrition & Bulletproof Habits, with High Performance Health Coach, Yuri Elkaim

From professional athlete to high performance health coach, Yuri Elkaim joins us today to talk about (almost) all things Bulletproof. In his goal to help 10,000,000 people become healthier, Yuri will share his take on raw food, the “fruit & veg” argument, exercise vs. rest, habits, and more! If you are an athlete (or biohacker) looking for 1 or 2 tips to take your performance to the next level, this is the show for you. Yuri Elkaim is a registered holistic nutritionist, fitness expert, and highly sought after high performance health coach. He’s also a former professional soccer player and served as the Head Strength & Conditioning and Nutrition Coach for men’s soccer at the University of Toronto for 7 seasons. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Aug 201346min

#54 Neurofeedback Technology, Best Biohack Yet, with Dr. Valdeane Brown

#54 Neurofeedback Technology, Best Biohack Yet, with Dr. Valdeane Brown

This episode is all about the most effective biohack I’ve experience yet – NeurOptimal® brain training. Dr. Valdeane Brown, Founder of NeurOptimal, came on the show to explain how this technology takes your performance to uncharted levels! The NeurOptimal brain trainer is the most powerful and affordable neurofeedback technology available. You will get to hear about the EEG technology and how it transforms your brain, upgrade athletic performance, and even help with migraines, PTSD, and abusive relationships. Does this sound too good to be true? Listen for yourself… Dr. Valdeane W. Brown is an internationally recognized "trainer of neurofeedback trainers", who has taught and consulted widely on personal and organizational transformation. With a Ph.D. in Clinical Psychology and a background in math, physics, computer programming, philosophy, yoga, meditation and martial arts, Dr. Brown brings a presence and precision to his work. This is further informed by a profound sense of compassion, a facility with energy dynamics and a deep commitment to revealing the elegant simplicity inherent in learning and transformation. Developer of the Five Phase Model and co-creator with his wife Sue of the Period 3 Approach to Clinical Neurofeedback, Dr. Brown has realized his vision of a truly comprehensive training system in NeurOptimal. His vision in bringing NeurOptimal to the world is to make personal transformation effortless and available to all. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Aug 20131h 1min

#53 Raw Vegan to Bulletproof Meat Eater - a beneficial transformation, with Kristen 'Raw' Suzanne

#53 Raw Vegan to Bulletproof Meat Eater - a beneficial transformation, with Kristen 'Raw' Suzanne

This episode brings to light an ex-vegan advocate’s journey to eating a mostly meat-embraced Bulletproof diet. Kristen ‘Raw’ Suzanne, author, popular blogger, and nutrition researcher, shared her former vegan assumptions, how easy or difficult it was to change, and the ethics of food. We also dove into a detailed conversations about liver meat, fertility issues on a vegan diet, how to stay Bulletproof when traveling with family, and how to nourish your kids the best way possible. In 2005, Kristen walked away from her corporate career in executive-level operations to focus on her true passion: healthy food. Already a vegan for two years, she turned her attention to the raw vegan cuisine and lifestyle, initially teaching classes and providing personal chef services, but as her online audience grew, she ultimately shifted to full-time blogging, recipe development, and eventually publishing 12 books on raw vegan diets. By 2012, concerns with her and her child's health forced her to reevaluate the nutritional claims made by advocates of raw and vegan diets. After Kristen introduced high quality animal products into her family's diet, she saw dramatic improvements almost immediately. Her family now eats a diet high in grass-fed beef and butter, bison, pastured eggs, and wild-caught seafood, while avoiding grains, gluten, and soy. While her personal transformation and conversion from vegan to omnivore has been controversial in the vegan and raw food community, Kristen has been on hiatus from blogging to spend time researching and fully exploring the nutritional and culinary aspects of eating in this new way for her family. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1 Aug 201357min

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