Dementia Matters27 Jun 2024

REVEALing APOE Results: Making Genetic Disclosures in Alzheimer’s Research

On this episode of Dementia Matters, Dr. Scott Roberts talks about disclosing genetic test results for APOE, a gene that can increase one’s likelihood of developing Alzheimer’s disease. While this information can be concerning, Dr. Roberts shares that it can empower individuals to take the necessary precautions to lower their risk of developing the disease. He discusses the Risk Evaluation and Education for Alzheimer’s Disease (REVEAL) study, walks us through the APOE disclosure process and shares how it is evolving with the development of new Alzheimer’s treatments.

Guest: Scott Roberts, PhD, interim chair, professor of health behavior & health education, University of Michigan School of Public Health

Show Notes

Read Dr. Roberts’ article, “Genetic risk assessment for adult children of people with Alzheimer's disease: the Risk Evaluation and Education for Alzheimer's Disease (REVEAL) study,” on the SageJournals website.

Decide if you’re a fit forAPOE testing using Virginia Tech’s ‘Gene Test or Not?’ decision aid tool, mentioned at 17:00 in the episode.

Learn more about Dr. Roberts on his University of Michigan profile.

Learn more about APOE by listening to our episode, “DNA Is Not Your Destiny: Genetics and Alzheimer’s Disease Risk,” with Dr. Corinne Engelman on our website.

Read “WRAP data used in study finding a distinct, genetic form of Alzheimer’s disease” on the Wisconsin Alzheimer’s Institute (WAI) website.

Connect with us

Find transcripts and more at our website.

Email Dementia Matters: dementiamatters@medicine.wisc.edu

Subscribe to the Wisconsin Alzheimer’s Disease Research Center’s e-newsletter.

Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer’s. All donations go toward outreach and production.

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(246)

Examining Environmental Factors' Effects on Cognition

New research is looking at the effects of environmental factors on the brain as we age. Dr. Kathryn Conlon joins the podcast to discuss how factors like air pollution and lead exposure can affect cogn...

22 Sep 42min

Blood Tests and Brain Scans and Biomarkers, Oh My! How Biomarkers are Changing Alzheimer’s Disease Clinical Trials

In recent years, the U.S. Food and Drug Administration (FDA) has approved new biomarker tools for Alzheimer’s disease, including blood tests and tracers for brain scans. How are these tools used in re...

8 Sep 45min

New Alzheimer’s Association Special Report Breaks Down How Americans Understand and Support their Brain Health

In recent years, public interest in brain health has increased. So how are Americans understanding brain health information and incorporating it into their own lives? This year, the Alzheimer’s Associ...

25 Aug 37min

Reflecting on 25 Years of the Wisconsin Registry for Alzheimer’s Prevention

Twenty-five years ago, a single participant enrolled in what would become the Wisconsin Registry for Alzheimer's Prevention (WRAP), now one of the largest and longest-running studies of Alzheimer's ri...

12 Aug 35min

How Dementia Caregiving Affects the Spousal Caregiver

Caring for those with dementia represents a major public health challenge, with caregivers, especially spouses, providing long-term, largely unpaid care. With caregiving stress linked to a decline in ...

28 Jul 39min

Managing the Medicine Cabinet: How Prescriptions Impact Cognition and Brain Health as We Age

Prescription medications, over-the-counter drugs and supplements are incredibly common among older adults, yet many of these routine treatments can unexpectedly impact cognitive function and brain hea...

14 Jul 35min

Taking a Deep Dive into Subjective Cognitive Decline

Dr. Jessen returns to the podcast to take a deeper dive into subjective cognitive decline (SCD). Aiming to cover everything relating to SCD, Dr. Jessen shares insights in prognosis, risk factors and h...

7 Jul 17min

Defining Subjective Cognitive Decline

Subjective cognitive decline (SCD) can be one of the earliest noticeable signs of Alzheimer's disease, yet SCD is not yet fully understood. To help us understand more, Dr. Frank Jessen, an expert in t...

30 Jun 30min