407: Biotransformation Myths and Realities in Hoppy and Non-Alcoholic Beers, with Dr. Peter Bircham

407: Biotransformation Myths and Realities in Hoppy and Non-Alcoholic Beers, with Dr. Peter Bircham

Two straight weeks of nothing but doctors on the Craft Beer & Brewing podcast? This week’s episode is another scientific barnburner with the head of R&D for Wellington’s Garage Project. Dr. Peter Bircham has been working in laboratory settings with yeast for many years, but for the past few he’s taken on an additional role beyond the academic, working on everything from building better Garage Project non-alcoholic beers to developing a testing regimen to evaluate new hop varietals in the Hāpi Research breeding program. In this episode, Bircham touches on:

  • beer biology
  • his systematic R&D process for developing novel brewing solutions
  • fermenting with less traditional ingredients like rice
  • testing regimens for new hop varieties with Hāpi Research
  • the benefits and limitations of biotransformation
  • breaking nitrogen regulation in non-GMO thiol production
  • yeast inbreeding to achieve genes of interest
  • cofermenting potential with unusual yeasts to unlock thiols

And more.

This episode is brought to you by:

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Berkeley Yeast (https://berkeleyyeast.com). Berkeley Yeast bioengineers ordinary strains and make them extraordinary—enhancing the flavors you want and eliminating the ones you don’t. Visit berkeleyyeast.com to learn more and start brewing with science on your side.
Old Orchard (https://www.oldorchard.com/brewer): As breweries expand beyond beer into other segments like mocktails and CBD beverages, Old Orchard is here to help. Whether trending flavor additions or nostalgic favorites, the next best thing is around the corner at Old Orchard. More information and free samples are waiting at oldorchard.com/brewer
Indie Hops (https://indiehops.com) Taste the modern flavors of Indie Hops at CBC, this year in Indianapolis. Join Indie in Indy for 14 incredible collab beers. Check out the full CBC beer lineup at www.indiehops.com and plan to stop by their booth #3122.
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Arryved (https://www.arryved.com) From taproom to distribution, Arryved gives breweries the tools to streamline operations and boost profits—all in one powerful platform. Want to see the latest innovations in action? Visit Arryved at CBC 2025, Booth 1865, where they’ll be pouring beers and showing off the future of brewery tech.
Ss Brewtech (https://SsBrewtech.com) Upgrade your fermentation game with Unitank 2.0 from Ss Brewtech. Available from 7-gallon up to 1-barrel sizes, Unitank 2.0 will be right at home in your homebrew set up or producing pilot batches at your commercial brewery. Visit Ss Brewtech.com to learn more!
Brewery Workshop (https://breweryworkshop.com) If you’re launching a brewery or acquiring an existing one, consider our brewery workshop and new brewery accelerator, September 14 through 17th in Fort Collins, Colorado. Visit breweryworkshop.com for more information and to secure your spot.

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Episoder(499)

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Episode 497: Todd Malloy and Robin Reed of Glenwood Canyon Match Lager Discipline with Brewpub Ingenuity for Medal-Winning Results

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Over the past 30 years, the Glenwood Canyon Brewpub has earned an impressive 18 Great American Beer Festival and eight World Beer Cup medals. Mostly recently, there have been back-to-back GABF golds i...

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496: Tonya Cornett and Ian Larkin of UPP Liquids Continue Their Tradition of Challenging Each Other and Winning Together

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31 Jul 1h 16min

495: Fermenting Expressive Hoppy Beers with Dry Yeast, in Partnership with White Labs

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28 Jul 1h 5min

494: Patrick Raasch of Sunriver Builds a Throughline of Refinement into Boldly Flavored Beers

494: Patrick Raasch of Sunriver Builds a Throughline of Refinement into Boldly Flavored Beers

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24 Jul 1h 16min

493: Podcast 493: Fresher Than Fresh! Jake Watt of Trap Door Utilizes Hot- and Cold-Side Techniques in Award-Winning Wet-Hopped IPAs

493: Podcast 493: Fresher Than Fresh! Jake Watt of Trap Door Utilizes Hot- and Cold-Side Techniques in Award-Winning Wet-Hopped IPAs

In both 2024 and 2025, Jake Watt, head brewer at Trap Door in Washougal, Washington, took home gold medals in the GABF fresh hop category for his beer, Fresher Than Fresh. Interestingly, the recipes f...

17 Jul 1h 23min

492: Building Better Gateways into Brewing, Produced in Partnership with Pinter

492: Building Better Gateways into Brewing, Produced in Partnership with Pinter

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