Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

Moderator: Jean-Marc Burgunder (Guemligen, Switzerland)Guest: Sandrine Humbert (Paris, France)In this week's episode, Burgunder and Humbert discuss the intriguing phenomenon of somatic expansion—the further increase of CAG repeat numbers in the gene involved in Huntington’s disease, particularly in the striatum. They explore the molecular mechanisms behind this process, as addressed in two recent research papers.Please find here the papers discussed in this episode: Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s diseaseand Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

Episoder(187)

Ep. 171: AI: A Virtual Elephant in the Room or a Game-Changer in Neuroscience?

Ep. 171: AI: A Virtual Elephant in the Room or a Game-Changer in Neuroscience?

Moderator: Alice Accorroni (Geneva, Switzerland) Guests: James Teo (London, UK), Giuseppe Jurman (Trento, Italy) In this special episode, Dr Alice Accorroni is joined by Professor James Teo and Prof...

19 Okt 202530min

Ep. 170: AI: Does it really concern neurologists?

Ep. 170: AI: Does it really concern neurologists?

Moderator: Raphael Wurm (Vienna, Austria) Guest: Francisco Cardoso (Belo Horizonte, Brasil) Artificial intelligence - hype or revolution? For this week’s special episode, Dr Raphael Wurm welcomes Pr...

12 Okt 202523min

Ep. 169: Cerebral circulation in space conditions and relationship to premature cerebrovascular ageing

Ep. 169: Cerebral circulation in space conditions and relationship to premature cerebrovascular ageing

Moderator: Roberta Balestrino (Milan, Italy) Guest: Nathalie Nasr (Poitiers, France) Join us as Dr Roberta Balestrino and Professor Nathalie Nasr takes us on a journey into the brain in space—uncover...

5 Okt 202520min

Ep. 168: Making Sense of the New ICD-11 Classification of Chronic Pain - From Concept to Clinical Practice

Ep. 168: Making Sense of the New ICD-11 Classification of Chronic Pain - From Concept to Clinical Practice

Moderator: Oxana Grosu (Chisinau, Moldova) Guest: Rolf-Detlef Treede (Mannheim, Germany) Prof. Treede and Dr. Grosu discuss the new ICD-11 classification of chronic pain, highlighting its significanc...

28 Sep 202522min

Ep. 167: Phantom Limb Pain - The Vanished Passenger

Ep. 167: Phantom Limb Pain - The Vanished Passenger

Moderator: Simone Vigneri (Bologna, Italy) Guest: Marshall Devor (Jerusalem, Israel) This episode explores the complex clinical features and neurobiology of phantom limb pain, highlighting key mechan...

21 Sep 202535min

Ep. 166: Pain When There Is a Neurodegeneration in the Brain – Assessment and Management of Pain in People with Dementia

Ep. 166: Pain When There Is a Neurodegeneration in the Brain – Assessment and Management of Pain in People with Dementia

Moderator: Katarina Rukavina (Berlin, Germany) Guest: Keela Herr (Iowa City, USA) How do we recognize and manage pain in people with dementia? In this episode of EAN Cast: Weekly Neurology, Katarina...

15 Sep 202519min

Ep. 165: Small Fiber Neuropathy - A Burning Problem

Ep. 165: Small Fiber Neuropathy - A Burning Problem

EAN moderator: Anna K. Szewczyk (Lublin, Poland) Guest:Grazia Devigili (Milan, Italy) Anna K. Szewczyk and Grazia Devigili discuss Small fiber neuropathy (SFN), a broad group of conditions affecting...

8 Sep 202524min

Ep. 164: EAN e-Learning Update

Ep. 164: EAN e-Learning Update

Moderators and guests: Barbara Tettenborn (Bern, Switzerland) and Roberta Balestrino (Milan, Italy) Barbara Tettenborn and Roberta Balestrino discuss the journey of the EAN e-learning platform, eanCa...

31 Aug 202521min

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